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Fight Aging! Newsletter, February 12th 2024
In conclusion, frailty is a dynamic process, and improved frailty and remaining robust are significantly associated with lower risk of all-cause mortality and cardiovascular death in older people. « Back to Top Greater Individual Wealth Correlates with Longer Life Expectancy https://www.fightaging.org/archives/2024/02/greater-individual-wealth-correlates-with-longer-life-expectancy/ Individual wealth correlates with life expectancy, with an effect size that is in the same ballpark as those related to lifestyle choices involving exercise, diet, and consequences thereof. It remains unclear...
Source: Fight Aging! - February 11, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

3D Printing In Medicine And Healthcare – The Ultimate List
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. See the impressive list of 3D-printed healthcare materials and medical equipment below! How does 3D printing in medicine work? 3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained in our article on bioprinting here. As technology evolves, researchers work on various solutions. For example, engineers from the University of Buffalo have ...
Source: The Medical Futurist - November 7, 2023 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine 3d printed biomaterial tissue engineering Video bioprinting GC1 Innovation Source Type: blogs

Top 8 Most Controversial Stories About Medical Innovations
I spend my days monitoring progress, analysing new trends, and learning about spectacular new initiatives. Needless to say: not just me, but the whole team of The Medical Futurist is fascinated by what we learn. And then sometimes there is a story that just melts the fuses at one or more team members – and our readers. Below I picked 8 of our favourite controversial stories from – almost exclusively – this year. It’s important to note that controversial doesn’t equal bad/useless. Sometimes it’s just not widely accepted (yet) and so exotic that they can surely provide a unique talking point at a...
Source: The Medical Futurist - December 13, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF 3d printing AI artificial intelligence bioprinting digital health CRISPR designer baby designer babies robotics in healthcare assisted dying DIY blood draw DIY blood test medical innovation deepfake Source Type: blogs

Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Nasal Endoscopy for Urgent and Complex ED Cases
Fiberoptics and endoscopy have changed the way we treat patients in the emergency department. Endoscopes are relatively easy to use, and can aid your diagnosis and treatment plan. Endoscopy may be useful in urgent cases, such as epistaxis, nasal foreign bodies, and ear debridement. It may also be helpful when dealing with more complicated presentations and critically ill patients, such as those with Ludwig's angina, epiglottis, tracheostomies, or those who need intubation.Fiberoptic tools are not just for surgeons and consultants. The endoscope has many uses in the emergency department, and we have a few tips and tricks...
Source: The Procedural Pause - October 28, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Focused Ultrasound and Intranasal Drug Delivery for Brain Cancer Therapy
Researchers at Washington University in St. Louis have developed a new method to bypass the blood-brain barrier and deliver drugs to the brain, which could be particularly useful in difficult-to-treat brain tumors. The technique involves administering drugs through an intranasal spray, meaning that the drug can travel directly into the brain along the trigeminal and olfactory nerves. Then, the researchers can use focused ultrasound to allow the drug to penetrate and accumulate in deeper layers of the tissue, and exert therapeutic benefit at the ultrasound-targeted region. Drug therapy for brain tumors is challenging, beca...
Source: Medgadget - September 10, 2018 Category: Medical Devices Authors: Conn Hastings Tags: ENT Neurology Neurosurgery Oncology Source Type: blogs

Fight Aging! Newsletter, August 6th 2018
In this study, we analyzed FGF21 levels and alterations in the expression of genes encoding components of the FGF21-responsive molecular machinery in adipose tissue from aged individuals so as to ascertain whether altered FGF21 responsiveness that develops with aging jeopardizes human health and/or accelerates metabolic disturbances associated with aging. We studied a cohort of 28 healthy elderly individuals (≥70 years) with no overt signs of metabolic or other pathologies and compared them with a cohort of 35 young healthy controls (≤40 years). Serum FGF21 levels were significantly increased in elderly individ...
Source: Fight Aging! - August 5, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Undoing Aging: Doug Ethell's Presentation on the Leucadia Therapeutics Approach to Treating Alzheimer's Disease
Doug Ethell has a clear and comparatively easily tested hypothesis on an important cause of Alzheimer's disease: that it results from the progressive failure of drainage of cerebrospinal fluid through one particularly crucial pathway in the skull. This traps ever greater levels of metabolic waste in the brain, such as amyloid-β, tau, and α-synuclein, and leads to the spectrum of well-known neurodegenerative diseases characterized by protein aggregates and resultant dysfunction and death of neurons. Dave Gobel of the Methuselah Foundation backed the first work on this hypothesis a few years back, and the result is ...
Source: Fight Aging! - August 1, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Precision Medicine and Public Health (from Precision Medicine and the Reinvention of Human Disease)
Excerpted fromPrecision Medicine and the Reinvention of Human DiseaseDespite having the most advanced healthcare technology on the planet, life expectancy in the United States is not particularly high. Citizens from most of the European countries and the highly industrialized Asian countries enjoy longer life expectancies than the United States. According to the World Health Organization, the United States ranks 31st among nations, trailing behind Greece, Chile, and Costa Rica, and barely edging out Cuba [42]. Similar rankings are reported by the US Central Intelligence Agency [43]. These findings lead us to infer that acc...
Source: Specified Life - February 6, 2018 Category: Information Technology Tags: cancer cancer vaccines precision medicine prevention public health Source Type: blogs

Fight Aging! Newsletter, December 18th 2017
In this study, we asked people in an open-ended way about their desire for longer life: Would you like to have more time? What age would you like to become? This was something more specific than asking about a preference for survival without reference to any length of time; about one's plans for the future; or whether people see the future as open or limited, as in studies of future time perspective. Our attempt was to discover whether there were preferred temporal spans with which older adults framed their futures and plans. The two-question series about extra years and desired age ("How old would you like to becom...
Source: Fight Aging! - December 17, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How naive T cells decline with age
AIM, within the Institute for Basic Science (IBS), released an intriguing paper in Scientific Reports, on August 2, describing a novel explanation to a issue known to immunologists for decades: What causes the particular decline in immunity in outdated individuals? As soon as we are born we are destined to age, it’s a natural law which everyone adheres in order to. As we grow older our immunity gradually diminishes to a point where it is no longer able to effectively orchestrate an immune system response to fight and extinguish pathogens. The flu vaccine, for example , is only 17 to 53 percent effective in people age...
Source: My Irritable Bowel Syndrome Story - August 2, 2016 Category: Gastroenterology Authors: Ken Tags: IBS News Source Type: blogs