Promoting Amphetamines for Over-Eating - What Could Possibly Go Wrong?
In this study, about 5% of patients given any dosage of Vyvanse had to discontinue its use because of adverse effects. 3/196 patients initially randomized to Vyvanse had serious adverse effects, and one patient died, apparently of an amphetamine overdose. Oddly, the article declared that the one death, due to methamphetamine overdose, was thought by a study investigator not to be related to treatment with another amphetamine, lisdexamfetamine. That makes little sense, given that in a randomized controlled trial, the presumption is that differences in groups given different treatments were caused by these ...
Source: Health Care Renewal - February 26, 2015 Category: Health Management Tags: clinical trials conflicts of interest deception evidence-based medicine FDA marketing Shire stealth marketing Source Type: blogs
TWiV 322: Postcards from the edge of the membrane
On episode #322 of the science show This Week in Virology, the TWiVodes answer listener email about hantaviruses, antivirals, H1N1 vaccine and narcolepsy, credibility of peer review, Bourbon virus, influenza vaccine, careers in virology, and much more.
You can find TWiV #322 at www.twiv.tv. (Source: virology blog)
Source: virology blog - February 1, 2015 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral Bourbon virus careers in virology crispr Dengue H1N1 hantavirus hepatitis C virus herpes simplex virus influenza vaccine influenza virus measles mumps narcolepsy NHL opossum patent peer r Source Type: blogs
You Won’t Believe Which Big-Name Groups are Opposed to Flu Vaccine Mandates
Conclusion
Millions of people are refusing vaccines, in record numbers, as they realize that vaccines are dangerous and ineffective. Now, unions and professional organizations are joining the ranks of anti-vaxers, at least with regard to mandatory vaccination. Those organizations value their members and know that they deserve choices about their bodies and their health care.
In return, those groups will be rewarded with a collectively healthier, more innovative work force, because their employees will not be forced to receive injections laced with toxic chemicals. Their employees will also know their ideas and opinions are...
Source: vactruth.com - January 17, 2015 Category: Allergy & Immunology Authors: Missy Fluegge Tags: Missy Fluegge Top Stories American Medical Association (AMA) Mandatory Vaccination National Childhood Vaccine Injury Act truth about vaccines Vaccine Adverse Events Reporting System (VAERS) Source Type: blogs
The road ahead for #FOAMed
This is a guest post written by Aidan Baron, aka @ALittleMedic, student-prehospitalist, one of the youngest FOAMers around and author of The Little Medic’s BlogExplosive growth. Ever increasing content. Trailblazing innovations. FOAM is undoubtedly going places: the question is, where?What does the future hold for the FOAM movement?Only time will tellAnd that’s the most exciting part.Our FOAM world has come a very long way, though there are still challenges ahead.There is an inherent risk of information overload, the ongoing process of developing a distinct identity and a steady stream of critiques; ranging from re...
Source: Life in the Fast Lane - December 12, 2014 Category: Emergency Medicine Authors: Chris Nickson Tags: Education aidan baron content consolidation delivering diversity FOAM FOAMed information overload quality sourcing quality Source Type: blogs
Upcoming 11/3/2014 FDA-DOC Meeting; Concerns About FDA Biosimilar Guidance(s)
At this point, I don't think its really necessary for me to repeat too much of the content that is already circulating within the diabetes online community of blogs about the forthcoming Monday, November 3, 2014 meeting from 1:00 pm-4:00 pm ET with the U.S. Food and Drug Administration (FDA). But I WILL say that collectively, over the past year, the diabetes patient community was able to accomplish something truly quite extraordinary. You should know about that, and even better, you also have a chance to participate in that!Specifically, in 2013, the diabetes online community started a petition (see http:...
Source: Scott's Web Log - October 20, 2014 Category: Endocrinology Tags: biogenerics Biosimilar diatribe FDA hypoglycemia Lantus Lilly Sanofi Source Type: blogs
The Shadow Boxer
Conclusion
The patient was admitted to a monitored setting with a diagnosis of GHB withdrawal. He had multiple episodes of agitation and combativeness during his admission. He was administered escalating doses of diazepam, a total of 480 mg of diazepam IV during his eight-day hospital stay. The patient recovered in eight days, and was referred to drug rehabilitation.
References
1. Dyer JE, Roth B, Hyma BA. Gamma-hydroxybutyrate withdrawal syndrome. Ann Emerg Med 2001;37(2):147.
2. Tarabar AF, Nelson LS. The gamma-hydroxybutyrate withdrawal syndrome. Toxicol Rev 2004;23(1):45.
3. Craig K, Gomez HF, et al. Severe gamma-h...
Source: The Tox Cave - October 2, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
The Shadow Boxer
Conclusion
The patient was admitted to a monitored setting with a diagnosis of GHB withdrawal. He had multiple episodes of agitation and combativeness during his admission. He was administered escalating doses of diazepam, a total of 480 mg of diazepam IV during his eight-day hospital stay. The patient recovered in eight days, and was referred to drug rehabilitation.
References
1. Dyer JE, Roth B, Hyma BA. Gamma-hydroxybutyrate withdrawal syndrome. Ann Emerg Med 2001;37(2):147.
2. Tarabar AF, Nelson LS. The gamma-hydroxybutyrate withdrawal syndrome. Toxicol Rev 2004;23(1):45.
3. Craig K, Gomez HF, et al. Severe g...
Source: The Tox Cave - October 2, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Sleeping, or not
I have problems sleeping these days. On a good night, I get to sleep for a solid 12 hours. I'm not kidding. I hope to do this once a week at least. Not this weekend. If I can, I save my big sleeping nights for the weekend because I don't have to get up in the morning.Friday night I slept from about 10-330. Then I dozed off and on until 6 when I gave up and got up. Last night, I slept from about 930 to 4. Then I couldn't sleep so I played games on my phone (because my phone was nagging me to get caught up on words with friends) for about half and hour and then dozed for a while and finally got back to sleep for a bit. I am ...
Source: Caroline's Breast Cancer Blog - July 20, 2014 Category: Cancer Tags: crabbiness crankiness lack of sleep medical tests Source Type: blogs
Kissing up
About a month ago I had a pre-med student spend an afternoon with me. Actually, it wasn't even that. After 2 hours she looked liked she was bored out of her mind (I'd warned her about that, but she still wanted to come in) and left at 3:00, saying she was meeting a friend for lunch. Anyway, I didn't hear from her again until yesterday, when this neatly typed note showed up in the mail:Dear Dr. Grumpy,Thank you for taking the time and allowing me to shadow you last month. I understand that having me there required a tremendous amount of time and effort, and I genuinely appreciate your support. My time with you was an unpar...
Source: Doctor Grumpy in the House - July 16, 2014 Category: Neurologists Authors: Grumpy, M.D. Source Type: blogs
Big Pharma pushes the Snake Oil approach
FDA has free-speech, safety issues to weigh in review of ‘off-label’ drug marketing rulesShould a pharmaceutical sales rep be allowed to tell a doctor that Topamax, a drug approved to treat seizures and prevent migraine headaches, might also help combat alcohol dependence? Or suggest the epilepsy drug Neurontin could also help treat bipolar disorders or insomnia? Or offer data showing that any number of other drugs could have uses beyond those listed on their labels?For decades, the answer overwhelmingly has been no. The Justice Department has aggressively pursued companies that run afoul of rules agains...
Source: PharmaGossip - July 10, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs
When Waking Up Becomes the Nightmare: Hypnopompic Hallucinatory Pain
In conclusion, to our knowledge this is the first report of a NREM parasomnia associated with painful paroxysms, for which we postulate the following underlying pathophysiological mechanism: an internal or external stimulus triggers arousal, facilitating the activation of innate motor pattern generators in the brainstem and activating somatosensory cortical areas to produce hypnopompic hallucinatory pain.So instead of the more typical visual hallucinations, the patient experiences pain hallucinations that originate.... where?? It seems to me that the sleep EEG could be analyzed more thoroughly, beyond merely ruling out sei...
Source: The Neurocritic - December 21, 2013 Category: Psychiatrists and Psychologists Authors: The Neurocritic Source Type: blogs
Dr James LeFanu writes
There is rather more than is immediately apparent in the recent grudging acknowledgement that the swine flu vaccine increased the risk of the serious sleeping disorder narcolepsy fourteen-fold – and that those affected (mainly children) are entitled to compensation.As many will recall, the threatened swine flu “pandemic” of 2009 proved something of a non-event, with only 10 per cent of the predicted number of cases and a miniscule mortality rate of 0.0005 per cent.This discrepancy between the dire warnings and what turned out to be among the mildest flu outbreaks of the past 100 years prompted an inquiry by...
Source: PharmaGossip - November 18, 2013 Category: Pharma Commentators Authors: insider Source Type: blogs
Seven Year-Old Vaccine-Injured Boy Refused Compensation For Not Being Disabled Enough
Conclusion
When it comes to compensation, many of the world’s governments shirk their responsibilities and turn a blind eye to suffering families. Families are repeatedly encouraged to apply for compensation even though the governments are fully aware that they will be refused compensation when they do.
It is families like the Hadfields who need the money the most. Josh is a child who has clearly been injured after receiving a vaccination recommended by the government and yet his family has been refused compensation because the VDPU has deemed him as not disabled enough. How disabled does a child have to be, for goodness...
Source: vactruth.com - October 11, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories Josh Hadfield Lord Ashley narcolepsy Pandemrix swine flu vaccine injury vaccine injury compensation Source Type: blogs
Gliadin: The Universal Human Poison
Autoimmunity is the process describing an immune response waged against our own organs. The complex collection of mechanisms consisting of T and B lymphocytes, antibodies, and others, meant to provide protection against viruses, bacteria, and other body invaders, is misdirected against proteins of the body’s organs, such as liver, pancreas, thyroid, or brain. Autoimmune conditions now affect 8% of the American population–it is increasingly looking like diseases of autoimmunity are out of control.
Dr Alessio Fasano was recently awarded the Linus Pauling Award, the highest award from the Institute for Functional...
Source: Wheat Belly Blog - October 7, 2013 Category: Cardiology Authors: Dr. Davis Tags: Autoimmunity Gliadin Source Type: blogs
Petition the FDA to Sponsor a Patient Meeting on Diabetes
By Web Team
The US Food and Drug Administration (FDA) has begun holding a series of patient meetings to better understand a variety of conditions, ranging from narcolepsy to fibromyalgia to irritable bowel syndrome. Diabetes, however, is not currently on the list of illnesses to be discussed.
In order change this, the Web site diaTribe has started an online petition where people can voice their support of the FDA sponsoring a patient meeting on diabetes.
According to the petition,
New therapies need to be investigated, tested, and brought to market, and as part of that process, the FDA must understand the daily challe...
Source: Diabetes Self-Management - September 14, 2013 Category: Diabetes Authors: Web Team Source Type: blogs
