2024 Kuan-Teh Jeang Memorial Lecture: The broad impact of innate immune receptors in viral infection, cancer and autoimmunity
Jenny Pan-Yun Ting is a Taiwanese-American immunologist and microbiologist at University of North Carolina. She is a highly cited researcher who studies the role of NLR genes in regulating inflammation and how nanoparticles and microparticles can be used as vaccine adjuvants. In memory of Kuan-Teh Jeang, the lecture will discuss the roles of multiple innate immune receptors in viral infection in mouse models and patients. The seminar will also describe the unexpected intrinsic roles of these receptors in adaptive T and B lymphocytes. The latter adects both cancer and autoimmunity, with implications for immunotherapeutics.I...
Source: Videocast - All Events - April 17, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Kuan-Teh Jeang Memorial Lecture: The broad impact of innate immune receptors in viral infection, cancer and autoimmunity
Jenny Pan-Yun Ting is a Taiwanese-American immunologist and microbiologist at University of North Carolina. She is a highly cited researcher who studies the role of NLR genes in regulating inflammation and how nanoparticles and microparticles can be used as vaccine adjuvants. In memory of Kuan-Teh Jeang, the lecture will discuss the roles ofmultiple innate immune receptors in viral infection in mouse models and patients. Theseminar will also describe the unexpected intrinsic roles of these receptors in adaptive Tand B lymphocytes. The latter adects both cancer and autoimmunity, with implications forimmunotherapeutics.For m...
Source: Videocast - All Events - April 3, 2024 Category: General Medicine Tags: Upcoming Events Source Type: video

Bubble-based ultrasound imaging technique
A rendering of an ultrasound imaging technique that uses nano-sized bubbles to distinguish macrophages -- a type of cell vital to nearly every function of the immune system -- from other cells in mammal tissue. [Research supported by U.S. National Science Foundation grant DMR 1845053.] Learn ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - December 1, 2023 Category: Science Source Type: video

How does the Plasma Membrane Participate in Receptor-Mediated Cell Signaling?
Cells are poised to respond to their physical environment and must distinguish specific stimuli from biological noise. Specific response mechanisms depend on collective molecular interactions that are regulated in time and space by the plasma membrane and its connections with the cytoskeleton and intracellular structures. Molecular stimuli engage their specific receptors to initiate a transmembrane signal, and the surrounding system efficiently rearranges to amplify this nanoscale interaction to microscale assemblies, yielding a cellular response that often reaches to longer length scales within the organism. A striking ex...
Source: Videocast - All Events - November 21, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Nanoscale rendering of graphene and chromium oxide
A nanoscale rendering of two materials, graphene (gray) and chromium oxide (blue), that collectively were used by a team of researchers to fabricate the first magneto-electric transistor. The red and green arrows represent spin, a magnetism-related property of electrons that can be read as a one or ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - November 18, 2023 Category: Science Source Type: video

Designing Nanoparticles to Probe and Cross Biological Barriers to Immunotherapy
The Mucosal Associated Immune System Engineering and Lymphatics (MAISEL) Lab ’ s research integrates nanotechnology, materials science, and tissue engineering with physiology, medicine, and immunology to probe lymphatics and extracellular barriers via novel ex vivo and in vitro models and nanoparticles. We are particularly focused on studying mucosal barriers to the therapeutic path from the mucosal lumen to the downstream lymph nodes and integrating the newly created knowledge to design immune modulatory therapeutic interventions. We have made significant progress in understanding how nanoparticle material properties li...
Source: Videocast - All Events - November 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Halide nanocrystal array emitting light
A rendering of a halide nanocrystal array emitting light. Researchers developed a technique to "grow" halide perovskite nanocrystals -- delicate materials with superior optoelectronic properties -- with precise control over the location and size of each individual crystal. The method allows the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - September 15, 2023 Category: Science Source Type: video

Vials of nanoparticle solution that can target cancer biomarkers
These vials of nanoparticle solution, shown against a projected tissue sample scan, can be used to target multiple cancer biomarkers by giving off two distinct signals when lit by one fluorescent wavelength -- a feature that could help doctors distinguish tumor borders and identify metastatic ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - September 9, 2023 Category: Science Source Type: video

Artist ’ s conceptualization of " Air-gen " effect
An artist’s conceptualization of the "Air-gen" effect, the ability to generate electricity from humidity in the air using material with nanopores less than 100 nanometers in diameter (spaghetti-like objects). The nanopores allow water molecules to pass through, effectively creating a charge ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 10, 2023 Category: Science Source Type: video

Reusable nanoparticle-coated sponge removes heavy metals from water
In a laboratory at Northwestern University, NSF-supported researchers have created a nanomaterial coating that can allow a commercially available sponge to be used for removing heavy metals from contaminated water.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 1, 2023 Category: Science Source Type: video

Biomedical Engineering Scientific Interest Group: Engineering mucus and innate lung defense
Gregg Duncan earned his Ph.D. in chemical engineering under the guidance of Michael Bevan at Johns Hopkins University in 2014. He then completed his postdoctoral training at Johns Hopkins School of Medicine in the Center for Nanomedicine directed by Justin Hanes. Dr. Duncan is currently an Assistant Professor in the Fischell Department of Bioengineering at the University of Maryland. Dr. Duncan leads the Respiratory Nano Bioengineering (RnB) lab, which aims to understand the airway microenvironment in health and disease to engineer new therapeutic strategies for obstructive lung diseases such as asthma, chronic obstructive...
Source: Videocast - All Events - May 23, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Smart coating warns of implant failure and kills bacteria
An illustration of a "smart" coating with bacteria-killing nanopillars on one side and strain-mapping flexible electronic sensors on the other. The coating, inspired by the antibacterial wings of dragonflies and cicadas, provides early warning of implant failure while killing infection-causing ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 19, 2023 Category: Science Source Type: video

Engineers have developed a new caterpillar-inspired robot.
Engineers at North Carolina State University have developed a caterpillar-bot that can move using a novel pattern of heated nanowires for control.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - April 12, 2023 Category: Science Source Type: video

Cone-shaped nano-sculpture created using software program
This cone-shaped nano-sculpture, no more than 2 millionths of an inch across, was created using a software program that constructs tiny 3D objects in a variety of unique shapes using DNA molecules. [Research supported by U.S. National Science Foundation grants CCF 1909848, OAC 1931487, CCF ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - March 4, 2023 Category: Science Source Type: video

Vase nano-sculpture created using software program
This vase nano-sculpture, no more than 2 millionths of an inch across, was created using a software program that constructs tiny 3D objects in a variety of unique shapes using DNA molecules. [Research supported by U.S. National Science Foundation grants CCF 1909848, OAC 1931487, CCF 2113941 and ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - March 3, 2023 Category: Science Source Type: video