Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients
Conditions: MRI Scan Interventions: Drug: MT218 injection Sponsors: Molecular Theranostics LLC; Emory University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 15, 2024 Category: Research Source Type: clinical trials
An Observational Study to Collect Information on the Safety of Gadolinium-Based Contrast Agents in Patients in India
Conditions: Contrast Enhancement in Magnetic Resonance Imaging Interventions: Drug: GBCAs Sponsors: Bayer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 13, 2024 Category: Research Source Type: clinical trials
Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma
Conditions: Oropharynx Cancer, Stage I Interventions: Biological: Atezolizumab; Procedure: Transoral Surgery with cervical lymphadenctomy (neck dissection); Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging Sponsors: Emory University; National Cancer Institute (NCI); Genentech, Inc. Suspended (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials
Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking
Conditions: Depressive Disorder, Major Interventions: Behavioral: functional magnetic resonance imaging (fMRI) Sponsors: Laureate Institute for Brain Research, Inc. Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials
Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung Cancer
Conditions: Advanced Lung Non-Small Cell Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8 Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Drug: Carfilzomib; Procedure: Computed Tomography; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Sotorasib Sponsors: City of Hope Medical Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials
Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma
Conditions: Diffuse Large B-Cell Lymphoma; High Grade B-Cell Lymphoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration and Biopsy; Procedure: Computed Tomography; Drug: Cyclophosphamide; Drug: Doxorubicin; Procedure: Echocardiography; Drug: Etoposide; Procedure: Magnetic Resonance Imaging; Biological: Mosunetuzumab; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography; Drug: Prednisone; Drug: Vincristine Sponsors: OHSU Knight Cancer Institute; Genentech, Inc.; Oregon Health and Science University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials
Venetoclax, Rituximab and Nivolumab in Combination for the Treatment of Richter's Transformation Arising From Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Conditions: Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Chronic Lymphocytic Leukemia; Richter Syndrome; Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma; Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Biopsy; Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging; Biological: Nivolumab; Procedure: Positron Emission Tomography; Biological: Rituximab; Drug: Venetoclax Sponsors: Northwestern University; National Cancer Institute (NCI); Brist...
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials
Physiology of Human Brain Connectivity
Conditions: Healthy Interventions: Device: Single-pulse transcranial magnetic stimulation (spTMS); Device: Paired associative stimulation (PAS); Diagnostic Test: Magnetic resonance imaging (MRI) Sponsors: Massachusetts General Hospital; National Institute of Neurological Disorders and Stroke (NINDS) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy
Conditions: Transcranial Direct Current Stimulation; EEG; Functional Magnetic Resonance Imaging; Refractory Epilepsy; Transcranial Magnetic Stimulation Interventions: Device: Active Comparator: Unilateral real High definition transcranial direct current stimulation; Device: Active Comparator: Bilateral real High definition transcranial direct current stimulation; Device: Sham Comparator: Sham High definition transcranial direct current stimulation Sponsors: Anhui Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2024 Category: Research Source Type: clinical trials
Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Primary Mediastinal Large B-Cell Lymphoma; Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Biological: Epcoritamab; Procedure: Magnetic Resonance Imaging; Other: Patient Observation; Procedure: Positron Emission Tomography Sponsors: Academic and Community Cancer Research United Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials
Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions: Castration-Resistant Prostate Carcinoma; Metastatic Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 Interventions: Biological: Anti-STEAP1 CAR T-cells; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Scan; Procedure: Computed Tomography; Drug: Cyclophosphamide; Procedure: Echocardiography; Drug: Enzalutamide; Drug: Fludarabine; Procedure: Leukapheresis; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Procedure: Positron Emission Tomography Sponsors: Fred Hutchinson Cancer Center; PromiCell Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 1, 2024 Category: Research Source Type: clinical trials
Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma
Conditions: Recurrent Multiple Myeloma; Refractory Multiple Myeloma Interventions: Drug: Iberdomide; Biological: Belantamab Mafodotin; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Procedure: Bone Marrow Biopsy; Procedure: Bone Marrow Aspiration; Procedure: Biospecimen Collection Sponsors: Alliance for Clinical Trials in Oncology; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 30, 2024 Category: Research Source Type: clinical trials
Effectiveness and brain mechanism of multi-target transcranial alternating current stimulation (tACS) on motor learning in stroke patients: study protocol for a randomized controlled trial
This study aims to ascertain whether multi-target tACS is more effective than single-target stimulation in stroke patients and to further explore the potential underlying brain mechanisms by using techniques such as transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI).MethodsThis study employs a double-blind, sham-controlled, randomized controlled trial design with a 2-week intervention period. Both participants and outcome assessors will remain unaware of treatment allocation throughout the study. Thirty-nine stroke patients will be recruited and randomized into three distinct groups, including the...
Source: Trials - January 30, 2024 Category: Research Source Type: clinical trials
Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China
Conditions: BPPV; Vertigo; Vertigo, Peripheral Interventions: Device: Simultaneous cortico-spinal magnetic resonance imaging, Serum Sponsors: First Affiliated Hospital Xi ' an Jiaotong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 29, 2024 Category: Research Source Type: clinical trials
Magnetic Resonance Imaging and Ultrasound Comparison With Load Evaluation
Conditions: Muscular Dystrophy, Facioscapulohumeral Interventions: Diagnostic Test: Muscle ultrasound with surface electromyography and dynamometry; Diagnostic Test: MRI scan Sponsors: Radboud University Medical Center; Solve FSHD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 26, 2024 Category: Research Source Type: clinical trials
