80-Year-Old Man With Vision Loss
An 80-year-old man presented to the emergency department with a 1-week history of progressive, transient, monocular vision loss, binocular diplopia, transient headache, and lightheadedness. Clinical comorbidities included obesity, hypertension, hyperlipidemia, former tobacco smoking, and femoral popliteal artery bypass surgery. He also had bilateral cataract surgery the month before presentation, which occurred without complications. Upon presentation, the patient ’s medications included aspirin 325 mg daily (prescribed after bypass surgery), hydrochlorothiazide 25 mg daily, lansoprazole 15 mg daily, losartan 25 mg twice...
Source: Mayo Clinic Proceedings - June 6, 2023 Category: Internal Medicine Authors: Audrey M. Blazek, Robert J. Haemmerle, James F. Meschia Tags: Residents ’ Clinic Source Type: research
Spatially confining copper nanoclusters in porous ZrO < sub > 2 < /sub > for fluorescence/colorimetry/smartphone triple-mode detection of metoprolol tartrate
Biosens Bioelectron. 2023 Apr 5;231:115290. doi: 10.1016/j.bios.2023.115290. Online ahead of print.ABSTRACTSensitive detection of metoprolol tartrate (MPT) is extremely urgent in the therapy of cardiovascular diseases to guarantee the curative effectiveness. Herein, porous ZrO2 was first employed as a matrix to spatially confine CuNCs (ZrO2@CuNCs), which simultaneously ameliorated the emission intensity and stability of CuNCs. Benefiting from the inner filter effect (IFE) and dynamic quenching effect (DQE) between ZrO2@CuNCs and AuNPs and the color fading of AuNPs induced by MPT, fluorometric and colorimetric methods for s...
Source: Biosensors and Bioelectronics - April 9, 2023 Category: Biotechnology Authors: Songrui Li Huifeng Zhang Zhenzhen Huang Qiong Jia Source Type: research
Spatially confining copper nanoclusters in porous ZrO < sub > 2 < /sub > for fluorescence/colorimetry/smartphone triple-mode detection of metoprolol tartrate
Biosens Bioelectron. 2023 Apr 5;231:115290. doi: 10.1016/j.bios.2023.115290. Online ahead of print.ABSTRACTSensitive detection of metoprolol tartrate (MPT) is extremely urgent in the therapy of cardiovascular diseases to guarantee the curative effectiveness. Herein, porous ZrO2 was first employed as a matrix to spatially confine CuNCs (ZrO2@CuNCs), which simultaneously ameliorated the emission intensity and stability of CuNCs. Benefiting from the inner filter effect (IFE) and dynamic quenching effect (DQE) between ZrO2@CuNCs and AuNPs and the color fading of AuNPs induced by MPT, fluorometric and colorimetric methods for s...
Source: Biosensors and Bioelectronics - April 9, 2023 Category: Biotechnology Authors: Songrui Li Huifeng Zhang Zhenzhen Huang Qiong Jia Source Type: research
Spatially confining copper nanoclusters in porous ZrO < sub > 2 < /sub > for fluorescence/colorimetry/smartphone triple-mode detection of metoprolol tartrate
Biosens Bioelectron. 2023 Apr 5;231:115290. doi: 10.1016/j.bios.2023.115290. Online ahead of print.ABSTRACTSensitive detection of metoprolol tartrate (MPT) is extremely urgent in the therapy of cardiovascular diseases to guarantee the curative effectiveness. Herein, porous ZrO2 was first employed as a matrix to spatially confine CuNCs (ZrO2@CuNCs), which simultaneously ameliorated the emission intensity and stability of CuNCs. Benefiting from the inner filter effect (IFE) and dynamic quenching effect (DQE) between ZrO2@CuNCs and AuNPs and the color fading of AuNPs induced by MPT, fluorometric and colorimetric methods for s...
Source: Biosensors and Bioelectronics - April 9, 2023 Category: Biotechnology Authors: Songrui Li Huifeng Zhang Zhenzhen Huang Qiong Jia Source Type: research
76-Year-Old Woman With Hemoptysis
A 76-year-old woman presented with 2 years of hemoptysis that had been increasing in frequency until it was happening on a daily basis. She had also experienced new hypoxia, exertional dyspnea, fatigue, and weight loss. Her past medical history was pertinent for severe scoliosis, remote myocardial infarction, heart failure with preserved ejection fraction (HFpEF), mild aortic stenosis, hypertension, and chronic kidney disease stage IV. She had no history of atrial fibrillation. Her medications included aspirin, high-intensity atorvastatin, furosemide, metoprolol tartrate, and lisinopril. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - October 19, 2022 Category: Internal Medicine Authors: Jwan A. Naser, Delvise T. Fogwe, Kara L. Dupuy-McCauley Tags: Residents ’ clinic Source Type: research
[ASAP] Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity
Chemical Research in ToxicologyDOI: 10.1021/acs.chemrestox.2c00052 (Source: Chemical Research in Toxicology)
Source: Chemical Research in Toxicology - May 16, 2022 Category: Toxicology Authors: Xiaonan Li, Gang Xing, Xinxin Guo, Yang Wang, Zixia Hu, Maosheng Cheng, Ying Peng, and Jiang Zheng Source Type: research
Role of Hesperidin and Fresh Orange juice in altering the bioavailability of Beta-Blocker, Metoprolol Tartrate. An invivo model
Xenobiotica. 2022 Apr 21:1-19. doi: 10.1080/00498254.2022.2067507. Online ahead of print.ABSTRACT1. The aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits.2. Metoprolol tartrate (10mg/kg) was given orally to rabbits with hesperidin (10mg/Kg) and with orange juice (6ml/Kg) separately.3. The plasma concentrations of metoprolol tartrate was determined using Reverse Phase-High Performance Liquid Chromatography at 1.5, 1, 2, 4 and 6 hours and the pharmacokinetic parameters were studied.4. In comparison to the control group, the AUC of ...
Source: Xenobiotica - April 21, 2022 Category: Research Authors: Rabiha Salam Syeda Nayyab Batool Rizvi Naqi Hussain Shama Firdous Muhammad Zaheer Muhammad Naeem Source Type: research
Role of Hesperidin and Fresh Orange juice in altering the bioavailability of Beta-Blocker, Metoprolol Tartrate. An invivo model
Xenobiotica. 2022 Apr 21:1-19. doi: 10.1080/00498254.2022.2067507. Online ahead of print.ABSTRACT1. The aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits.2. Metoprolol tartrate (10mg/kg) was given orally to rabbits with hesperidin (10mg/Kg) and with orange juice (6ml/Kg) separately.3. The plasma concentrations of metoprolol tartrate was determined using Reverse Phase-High Performance Liquid Chromatography at 1.5, 1, 2, 4 and 6 hours and the pharmacokinetic parameters were studied.4. In comparison to the control group, the AUC of ...
Source: Xenobiotica - April 21, 2022 Category: Research Authors: Rabiha Salam Syeda Nayyab Batool Rizvi Naqi Hussain Shama Firdous Muhammad Zaheer Muhammad Naeem Source Type: research
Role of Hesperidin and Fresh Orange juice in altering the bioavailability of Beta-Blocker, Metoprolol Tartrate. An invivo model
Xenobiotica. 2022 Apr 21:1-19. doi: 10.1080/00498254.2022.2067507. Online ahead of print.ABSTRACT1. The aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits.2. Metoprolol tartrate (10mg/kg) was given orally to rabbits with hesperidin (10mg/Kg) and with orange juice (6ml/Kg) separately.3. The plasma concentrations of metoprolol tartrate was determined using Reverse Phase-High Performance Liquid Chromatography at 1.5, 1, 2, 4 and 6 hours and the pharmacokinetic parameters were studied.4. In comparison to the control group, the AUC of ...
Source: Xenobiotica - April 21, 2022 Category: Research Authors: Rabiha Salam Syeda Nayyab Batool Rizvi Naqi Hussain Shama Firdous Muhammad Zaheer Muhammad Naeem Source Type: research
Role of Hesperidin and Fresh Orange juice in altering the bioavailability of Beta-Blocker, Metoprolol Tartrate. An invivo model
Xenobiotica. 2022 Apr 21:1-19. doi: 10.1080/00498254.2022.2067507. Online ahead of print.ABSTRACT1. The aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits.2. Metoprolol tartrate (10mg/kg) was given orally to rabbits with hesperidin (10mg/Kg) and with orange juice (6ml/Kg) separately.3. The plasma concentrations of metoprolol tartrate was determined using Reverse Phase-High Performance Liquid Chromatography at 1.5, 1, 2, 4 and 6 hours and the pharmacokinetic parameters were studied.4. In comparison to the control group, the AUC of ...
Source: Xenobiotica - April 21, 2022 Category: Research Authors: Rabiha Salam Syeda Nayyab Batool Rizvi Naqi Hussain Shama Firdous Muhammad Zaheer Muhammad Naeem Source Type: research
Role of hesperidin and fresh orange juice in altering the bioavailability of beta-blocker, metoprolol tartrate. An < em > in vivo < /em > model
Xenobiotica. 2022 Apr 26:1-6. doi: 10.1080/00498254.2022.2067507. Online ahead of print.ABSTRACTThe aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits.Metoprolol tartrate (10 mg/kg) was given orally to rabbits with hesperidin (10 mg/kg) and with orange juice (6 mL/kg) separately.The plasma concentrations of metoprolol tartrate were determined using reverse phase-high performance liquid chromatography at 1.5, 1, 2, 4, and 6 h, and the pharmacokinetic parameters were studied.In comparison to the control group, the AUC of metoprolol ...
Source: Xenobiotica - April 21, 2022 Category: Research Authors: Rabiha Salam Syeda Nayyab Batool Rizvi Naqi Hussain Shama Firdous Muhammad Zaheer Muhammad Naeem Source Type: research
Amiodarone/metoprolol-tartrate
(Source: Reactions Weekly)
Source: Reactions Weekly - April 1, 2022 Category: Drugs & Pharmacology Source Type: research
Evaluation of a Beta-blocker - Edema - Loop Diuretic Prescribing Cascade: A Prescription Sequence Symmetry Analysis
CONCLUSIONS: We observed excess use of loop diuretics following beta-blocker initiation that was only partially explained by secular trends or hypertension progression.PMID:35106529 | DOI:10.1093/ajh/hpac013 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 2, 2022 Category: Cardiology Authors: Scott Martin Vouri Earl J Morris Xinyi Jiang Ann-Kathrin Hofer Stephan Schmidt Carl Pepine Almut G Winterstein Steven M Smith Source Type: research
Evaluation of a Beta-blocker - Edema - Loop Diuretic Prescribing Cascade: A Prescription Sequence Symmetry Analysis
CONCLUSIONS: We observed excess use of loop diuretics following beta-blocker initiation that was only partially explained by secular trends or hypertension progression.PMID:35106529 | DOI:10.1093/ajh/hpac013 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 2, 2022 Category: Cardiology Authors: Scott Martin Vouri Earl J Morris Xinyi Jiang Ann-Kathrin Hofer Stephan Schmidt Carl Pepine Almut G Winterstein Steven M Smith Source Type: research
