Phytochemical investigation and antitumor activity of coumarins from Sicilian accession of < em > Ferulago nodosa < /em > (L.) Boiss. roots
Nat Prod Res. 2023 May 21:1-12. doi: 10.1080/14786419.2023.2213808. Online ahead of print.ABSTRACTFerulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area being present in Crete, Greece, Albania, and probably in Macedonia. From the roots of this accession of species, not previously investigated, four coumarins, grandivittin, aegelinol benzoate, felamidin and aegelinol, and two terpenoids, (2E)-3-methyl-4-[(3-methyl-1-oxo-2-buten-1yl)oxy]-2-butenoic acid and pressafonin-A, were isolated and spectroscopically characterized. The last one was never detected in Ferulago species. The evaluation...
Source: Natural Product Research - May 22, 2023 Category: Biochemistry Authors: Natale Badalamenti Alessandro Vaglica Antonella Porrello Antonella Maggio Maurizio Bruno Marianna Lauricella Antonella D'Anneo Source Type: research

Phytochemical investigation and antitumor activity of coumarins from Sicilian accession of < em > Ferulago nodosa < /em > (L.) Boiss. roots
Nat Prod Res. 2023 May 21:1-12. doi: 10.1080/14786419.2023.2213808. Online ahead of print.ABSTRACTFerulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area being present in Crete, Greece, Albania, and probably in Macedonia. From the roots of this accession of species, not previously investigated, four coumarins, grandivittin, aegelinol benzoate, felamidin and aegelinol, and two terpenoids, (2E)-3-methyl-4-[(3-methyl-1-oxo-2-buten-1yl)oxy]-2-butenoic acid and pressafonin-A, were isolated and spectroscopically characterized. The last one was never detected in Ferulago species. The evaluation...
Source: Natural Product Research - May 22, 2023 Category: Biochemistry Authors: Natale Badalamenti Alessandro Vaglica Antonella Porrello Antonella Maggio Maurizio Bruno Marianna Lauricella Antonella D'Anneo Source Type: research

Phytochemical investigation and antitumor activity of coumarins from Sicilian accession of < em > Ferulago nodosa < /em > (L.) Boiss. roots
Nat Prod Res. 2023 May 21:1-12. doi: 10.1080/14786419.2023.2213808. Online ahead of print.ABSTRACTFerulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area being present in Crete, Greece, Albania, and probably in Macedonia. From the roots of this accession of species, not previously investigated, four coumarins, grandivittin, aegelinol benzoate, felamidin and aegelinol, and two terpenoids, (2E)-3-methyl-4-[(3-methyl-1-oxo-2-buten-1yl)oxy]-2-butenoic acid and pressafonin-A, were isolated and spectroscopically characterized. The last one was never detected in Ferulago species. The evaluation...
Source: Natural Product Research - May 22, 2023 Category: Biochemistry Authors: Natale Badalamenti Alessandro Vaglica Antonella Porrello Antonella Maggio Maurizio Bruno Marianna Lauricella Antonella D'Anneo Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research

Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years
CONCLUSIONS: The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted.PMID:37114688 | DOI:10.24953/turkjped.2022.594 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - April 28, 2023 Category: Pediatrics Authors: Violeta Anastasovska Milica Pesevska Nikolina Zdraveska Biljana Zafirova Jasmina Meceska Jovcevska Mirjana Kocova Source Type: research