Corrigendum to "A repeated cross-sectional study of factors associated with pregabalin-positive poisoning deaths in Ireland" [Drug Alcohol Depend. 206 (2020) 107741] - Lynn E, Cousins G, Lyons S, Bennett KE.
The authors regret that there were two typographical errors in the Results section of the abstract of the published article. Please see below for the corrected abstract in full. Background: The increasing use of pregabalin and the presence of pre... (Source: SafetyLit)
Source: SafetyLit - March 30, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

La FDA advierte acerca de problemas respiratorios graves con los medicamentos para convulsiones y dolor neural gabapentina (Neurontin, Gralise, Horizant) y pregabalina (Lyrica, Lyrica CR)
La Administraci ón de Alimentos y Medicamentos de EE. UU. (FDA) advierte que los pacientes con factores de riesgo respiratorio que usan gabapentina (Neurontin, Gralise, Horizant) o pregabalina (Lyrica, Lyrica CR) pueden sufrir graves dificultades respiratorias. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 30, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Withdrawal, dependence and adverse events of antidepressants: lessons from patients and data
Tolerability, withdrawal effects and dependence on prescription medication is an important topic of current scientific and clinical debate, as highlighted by the recent report published on September 2019 by Public Health England (https://www.gov.uk/government/publications/prescribed-medicines-review-report).1 This was a mixed methods public health review of available evidence in adults focusing on specific issues of dependence and withdrawal associated with five groups of medications: (1) benzodiazepines, (2) z-drugs, (3) gabapentin and pregabalin, (4) opioids and (5) antidepressants. The evidence included in the review co...
Source: Current Awareness Service for Health (CASH) - January 24, 2020 Category: Consumer Health News Source Type: news

FDA warns about serious breathing problems with seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR)
Listen to an audio podcast of the December 19, 2019 FDA Drug Safety Communication warning that serious breathing difficulties may occur in patients using seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR) who have respiratory risk factors. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 2, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Off-Label Use of Gabapentinoids: A New Paradigm
Several of the hot topics in geriatrics are pain management, medication reduction/deprescribing, and use of off-label medications. Best-practice use of gabapentinoids — gabapentin (Neurontin) and pregabalin (Lyrica) — comfortably fits into all three categories. Examination of the evidence may help health care practitioners make better decisions when prescribing these medications. (Source: Caring for the Ages)
Source: Caring for the Ages - December 25, 2019 Category: Health Management Authors: Daniel Haimowitz, Jeanne Manzi Source Type: news

Neurontin, Gralise, Horizant (gabapentin) and Lyrica, Lyrica CR (pregabalin): Drug Safety Communication - Serious Breathing Problems
FDA is warning that serious breathing difficulties may occur in patients using gabapentin or pregabalin who have respiratory risk factors. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 20, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA warns about serious breathing problems with seizure and nerve pain medicines gabapentin (Neurontin, Gralise, Horizant) and pregabalin (Lyrica, Lyrica CR)
Taking gabapentin or pregabalin with opioids, anxiety meds or antidepressants, or if you have lung issues or are elderly, can lead to serious breathing problems. Watch for breathing issues, confusion, dizziness, or extreme sleepiness. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 19, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

A repeated cross-sectional study of factors associated with pregabalin-positive poisoning deaths in Ireland - Lynn E, Cousins G, Lyons S, Bennett KE.
In this study we examined factors associated with pregabalin-positive poisoning deaths (P... (Source: SafetyLit)
Source: SafetyLit - November 28, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Steep Jump in Gabapentinoid Use Among US Patients With Cancer Steep Jump in Gabapentinoid Use Among US Patients With Cancer
The use of gabapentin and pregabalin doubled between 2005 and 2015 among US patients with cancer; experts say these drugs may be appropriate, but warn about adverse effects and potential for abuse.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 7, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

The impact of the sepsis on female urogenital system: the role of pregabalin
The aim of the study was to investigate the oxidative damage and inflammatory effects of sepsis on the urogenital system in the Lipopolysaccharide (LPS)-induced sepsis model and ameliorating role of Pregabalin (PGB). These findings demonstrated that sepsis caused oxidative stress and inflammation in the urogenital tissues. We have revealed that PGB ameliorated tissue damage caused by sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 30, 2019 Category: Consumer Health News Source Type: news

Two Sentenced for Participating in Online Drug Distribution and Money Laundering Scheme
Zuned Sunesra, Mumbai, India, Taimur Khan, Surrey, British Columbia, conspiracy, pharmacy websites, online pharmacy, emedoutlet.com, Asian Capital Equities, Soma, Provigil, Darvocet, Darvocet-N, Meridia, Lyrica, mygiftcard.biz, illegal medications, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 11, 2019 Category: Medical Law Authors: DOJ Source Type: news

Dishing out more drugs won ’t stop the pain. Doctors need new tools | Ann Robinson
As a GP, I know opioids have their place. But we shouldn ’t be complacent about a US-style crisis happening in BritainGrowing concern about the prescription of drugs that cause dependence has been backed up by a recent report from Public Health England (PHE). The agencydiscovered that in 2017-18, 13% of adults in England received at least one prescription for opioids such as morphine or oxycodone (although this represented a slight downturn in prescribing after a long upward trend). Other drug classes were implicated too, with 25% of adults prescribed one or more of the following drugs: benzodiazepines (such as Valium), ...
Source: Guardian Unlimited Science - September 15, 2019 Category: Science Authors: Ann Robinson Tags: Opioids GPs NHS Doctors Health Society Drugs policy Politics Science UK news Source Type: news

FDA approves first generics of Lyrica
(pregabalin) (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 11, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Pregabalin, Ketamine to Prevent Pain After Cardiac Surgery Pregabalin, Ketamine to Prevent Pain After Cardiac Surgery
This study assessed the effect of a prolonged regimen of preventive analgesia with pregabalin alone or in combination with ketamine.Anesthesiology (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 8, 2019 Category: Surgery Tags: Anesthesiology Journal Article Source Type: news

FDA Grants First Approvals for Generic Versions of Lyrica
Title: FDA Grants First Approvals for Generic Versions of LyricaCategory: Health NewsCreated: 7/23/2019 12:00:00 AMLast Editorial Review: 7/24/2019 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - July 24, 2019 Category: Anesthesiology Source Type: news