Efficacy of chloroquine versus lopinavir/ritonavir in mild/general COVID-19 infection: a prospective, open-label, multicenter, randomized controlled clinical study
DiscussionThis experiment should reveal the efficacy and safety of using chloroquine versus lopinavir/ritonavir for patients with mild/general COVID-19 infection. If the new treatment including chloroquine shows a higher rate of throat-swab SARS-CoV-2 real-time fluorescent reverse transcription polymerase chain reaction (RT-PCR) negativity and is safe, it could be tested as a future COVID-19 treatment.Trial registrationChinese Clinical Trial Registry, ID:ChiCTR2000029741. Registered on 11 February 2020. (Source: Trials)
Source: Trials - July 7, 2020 Category: Research Source Type: clinical trials

A Study of Combination Therapies to Treat COVID-19 Infection
Conditions:   COVID;   COVID-19;   Corona Virus Infection;   Coronavirus Infection;   Coronavirus Sars-Associated as Cause of Disease Classified Elsewhere;   Coronavirus-19;   SARS-CoV 2;   SARS Pneumonia Interventions:   Drug: hydroxychloroquine;   Drug: Azithromycin;   Drug: Ritonavir;   Drug: Lopinavir Sponsors:   ProgenaBiome;   Big Corona Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 7, 2020 Category: Research Source Type: clinical trials