The Effect of Different Preparation Methods on the In Vitro and In Vivo Performance of Solid Dispersion Formulations (U01)
The objective of this study is to investigate the in vitro and in vivo performance for solid dispersion drug products made from different manufacturing processes or polymer carriers, as well as their performance consistency during storage and among batches. The investigation should identify critical process parameters and critical quality attributes for solid dispersion made from different preparation methods, and develop discriminating analytical methods.
Detailed Descriptions:
The following studies should be conducted for the purpose of this project:
(1) Identify model drugs, and prepare amorphous solid dispersion us...
Source: Grants.gov - April 18, 2014 Category: Research Tags: Health Science and Technology and other Research and Development Source Type: funding
