Transurethral bipolar enucleation using a TUEB loop for large benign prostatic hyperplasia: a retrospective cohort study
ConclusionTUEB using a TUEB loop resulted in high levels of satisfaction regarding the enucleation efficiency, efficacy, and safety for BPH surgery regardless of the prostate size. TUEB should be considered one of the best treatment options for large BPH that is uncontrollable with medication. (Source: World Journal of Urology)
Source: World Journal of Urology - March 21, 2024 Category: Urology & Nephrology Source Type: research
Treatment patterns and prognosis in patients with Bacillus Calmette –Guérin-exposed high-risk non-muscle invasive bladder cancer: a real-world data analysis
ConclusionsThe newly proposed definition of BCG-exposed NMIBC may serve as a valuable disease subgroup for distinguishing significant gray areas, except in cases of BCG-unresponsive NMIBC. (Source: World Journal of Urology)
Source: World Journal of Urology - March 21, 2024 Category: Urology & Nephrology Source Type: research
Modified Retzius-sparing robot-assisted radical prostatectomy for cases with anterior tumor: a propensity score-matched analysis
ConclusionmRS-RARP seems to be an oncologically safe approach for patients with anterior PCa. Compared with the conventional approach, mRS-RARP approach shows benefits in the short-term postoperative UC recovery. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Unveiling the challenges of UTUC biopsies and cytology: insights from a global real-world practice study
ConclusionBiopsy results adequately predict high-grade and high-risk disease, but approximately one-third of patients are under-staged. Two-thirds of patients with low-grade URS-biopsy have high-risk stage disease, highlighting the need for improved diagnostics to better assess patient risk and guide treatment decisions.Clinical trial registration: The study was registered at ClinicalTrials.gov (ClinicalTrials.gov NCT02281188;https://clinicaltrials.gov/ct2/show/NCT02281188). (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
PSA-density, DRE, and PI-RADS 5: potential surrogates for omitting biopsy?
ConclusionIn PI-RADS 5 patients, PSA-D and cT-stage emerged as strong predictors of csPCA at biopsy. Moreover, when adding the threshold of PSA-D > 0,5 ng/ml/cc, all PI-RADS 5 patients were diagnosed with csPCA. Therefore, straight treatment for PCA can be considered, especially if risk-factors for biopsy-related complications such as obligatory dual platelet inhibition are present. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Multiparametric Magnetic Resonance Imaging in the follow-up of non-muscle-invasive bladder tumors after intravesical instillations: a promising tool
ConclusionsIn cases of doubtful cystoscopy after intravesical instillations, MRI appears to be relevant with good performance in differentiating post-therapeutic inflammatory changes from recurrent tumor lesions and could potentially allow avoiding unnecessary TURB. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Feasibility of stereotactic optical navigation for needle positioning in percutaneous nephrolithotomy
ConclusionsThe optical navigation system facilitated safe needle insertion but did not consistently ensure accurate one-attempt needle positioning for PCNL. Real-time visualization and trajectory correction may improve the technical success rate. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Gender inequality in genitourinary malignancies clinical trials leadership
ConclusionBetween 2000 and 2020, only 16.8% of urological cancer clinical trials were led by a female PI, perhaps reflective of a low percentage of senior female researchers in the fields of urology, oncology and radiation oncology. Universities, research institutes and funding agencies should work to improve mentorship, representation and opportunities for female investigators to encourage more involvement for female researchers in these clinical trials. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Incidence of complications and urinary incontinence following endoscopic enucleation of the prostate in men with a prostate volume of 80 ml and above: results from a multicenter, real-world experience of 2512 patients
ConclusionsPV has no influence on complication and UI rates following EEP. Age is risk factor of postoperative UI. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Asymptomatic bacteriuria prior to partial and radical nephrectomy: To screen or not to screen? Results from the national and multicenter TOCUS database
ConclusionOur research shows that screening and treating for ABU prior to radical or partial nephrectomy seems to be unnecessary to prevent postoperative UTI and SSI. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
What should the optimal access site be for percutaneous treatment of anterior lower pole calyx stones?
ConclusionsPercutaneous surgery utilising an access from a calyx distal to the stone may offer better clearance and lower morbidity rates for lower pole stones involving the anterior calyx. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Combination of urinary biomarkers and machine-learning models provided a higher predictive accuracy to predict long-term treatment outcomes of patients with interstitial cystitis/bladder pain syndrome
ConclusionMachine learning decision tree model provided a higher accuracy for predicting treatment outcome of patients with IC/BPS than logistic regression, and levels of 8-isoprostance, MCP-1, and 8-OHDG had the most important influence on accuracy. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
High-intensity focused ultrasound with visually directed power adjustment for focal treatment of localized prostate cancer: systematic review and meta-analysis
ConclusionLimited evidence from eight observational studies demonstrated that visually directed HIFU for focal treatment of localized prostate cancer was associated with a relatively low risk of complications and acceptable cancer control over medium-term follow-up. Comparative, long-term safety and effectiveness results with visually directed focal HIFU are lacking. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Real-world analysis of apalutamide-associated skin rash in Chinese patients with prostate cancer
ConclusionNearly one-third of Chinese patients experienced skin rash after taking apalutamide in our study. The poor health patients might have a higher incidence of apalutamide-associated skin rash. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Robotic YV plasty outcomes for bladder neck contracture vs. vesico-urethral anastomotic stricture
ConclusionRobotic YV plasty is feasible for both VUAS and BNC. While functional outcomes and stricture-free survival may be similar for both conditions, the perioperative outcomes were less favorable for VUAS patients. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
