Microstructural white matter abnormalities in overactive bladder syndrome evaluation with diffusion kurtosis imaging tract-based spatial statistics analysis
ConclusionDKI is a promising approach to the investigation of the pathophysiology of OAB and a potential biomarker for clinical diagnosis of OAB. (Source: World Journal of Urology)
Source: World Journal of Urology - January 13, 2024 Category: Urology & Nephrology Source Type: research

Ultrasound imaging of male urethral stricture disease: a narrative review of the available evidence, focusing on selected prospective studies
ConclusionSonourethrography is a cost-effective and safe technique allowing for a dynamic and three-dimensional urethra assessment. Yet, because of its limited value in detecting posterior urethral strictures, the standard urethrography should remain the basic ‘road-map’ prior to surgery. It is an operator-dependent technique, which can provide detailed information on the length, location, and extent of spongiofibrosis without risks of exposure to ionizing radiation. (Source: World Journal of Urology)
Source: World Journal of Urology - January 13, 2024 Category: Urology & Nephrology Source Type: research

Relocation of lower pole renal stones helps improve the stone-free rate during flexible ureteroscopy with a low complication rate
ConclusionA satisfactory SFR with a relatively low complication rate was achieved by the relocation technique during the FURS procedure. (Source: World Journal of Urology)
Source: World Journal of Urology - January 13, 2024 Category: Urology & Nephrology Source Type: research

Pathways to paediatric urology subspecialisation: a study of casemix, incumbent attitudes and opinions
ConclusionThis study represents the first time that a cross-sectional cohort of paediatric urologists from different training backgrounds were compared to assess their productivity, practice patterns and attitudes. Paediatric urology is in a unique position to have two contributing specialities, with the ability to provide optimal transitional and lifelong care. We believe that there should be a strong emphasis on collaboration and to remove any historically-created barriers under policies of equity, diversity and inclusivity. (Source: World Journal of Urology)
Source: World Journal of Urology - January 13, 2024 Category: Urology & Nephrology Source Type: research

Comparisons of mpMRI, 68Ga-PSMA PET/CT and mpMRI combined with 68Ga-PSMA PET/CT in diagnosing prostate cancer based on tumor detection, localization and staging
ConclusionsWith postoperative pathology as reference,68Ga-PSMA PET/CT underestimates the local tumor staging. MpMRI combined with68Ga-PSMA PET/CT has no obvious advantages in detecting, localizing or staging prostate cancer compared with mpMRI. (Source: World Journal of Urology)
Source: World Journal of Urology - January 12, 2024 Category: Urology & Nephrology Source Type: research

Glycolate oxidase-1 gene variants influence the risk of hyperoxaluria and renal stone development
ConclusionGenetic variants of the GOX1 genes were associated with renal stone disease. In the presence of risk genotype and hyperoxaluria, the susceptibility to develop renal stone disease risk gets modulated. (Source: World Journal of Urology)
Source: World Journal of Urology - January 12, 2024 Category: Urology & Nephrology Source Type: research

Randomized, placebo-controlled, double-blinded study of prophylactic cranberries use in women with recurrent uncomplicated cystitis
ConclusionThe daily use of Cysticlean ™ 240 mg was associated with a reduction of UTIs and a prolongation of UTI-free survival compared to placebo treatment, supporting its use as prophylaxis in this patient population.Trial registrationClinicaltrials.gov, identifier NCT03032003. (Source: World Journal of Urology)
Source: World Journal of Urology - January 12, 2024 Category: Urology & Nephrology Source Type: research

Renal regenerative capacity related to stem cell reserve in nephrectomized rats
ConclusionsKidneys may pose a regenerative response to tissue/volume loss through its own CD90- and CD105-related stem cell reserve which mainly takes place in glomeruli and seems to have some interactions with Ki-67-related tubular proliferative process. This response supports that kidney stem cells may have a potential to overcome tissue/volume loss-related damage. (Source: World Journal of Urology)
Source: World Journal of Urology - January 11, 2024 Category: Urology & Nephrology Source Type: research

Factors predicting indistinct plane of surgical capsule in patients underwent HoLEP procedures
ConclusionPV is the most reliable factor to predict IP during HoLEP procedures. There is a high possibility of IP in patients with a PV less than 54  ml. (Source: World Journal of Urology)
Source: World Journal of Urology - January 11, 2024 Category: Urology & Nephrology Source Type: research

The effect of hospital caseload on perioperative mortality, morbidity and costs in bladder cancer patients undergoing radical cystectomy: results of the German nationwide inpatient data
ConclusionsCentralization of RC not only improves inpatient morbidity and mortality but also reduces hospital stay and costs. We propose a threshold of 50 RCs/year for optimal outcomes. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research

Endoscopic combined intrarenal surgery composed of micro-perc and retrograde intrarenal surgery in the treatment of complex kidney stones in children
ConclusionOur results demonstrate that Micro-ECIRS while patients are in the GMSV position is a safe and effective method for the treatment of complex children nephrolithiasis. However, all children made three hospital visits and received anesthesia three times. Further research is needed to confirm these findings. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research

Comparing the safety and efficacy of single-port versus multi-port robotic-assisted techniques in urological surgeries: a systematic review and meta-analysis
ConclusionSingle-port robotics appears to have similar perioperative outcomes to multi-port robotics in urological surgery. In radical prostatectomy, single-port robotics has shown some advantages, but the specific suitability of single-port robots for urological surgical types needs to be further explored. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research

Identification of biomarkers and potential therapeutic targets of kidney stone disease using bioinformatics
ConclusionThe 10 hub genes identified, especiallyLCN2, may be involved in kidney stone occurrence and development, and may provide new research targets for KSD diagnosis. Furthermore, KSD-related miRNAs may be targeted for the development of novel drugs for KSD treatment. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research

How does artificial intelligence master urological board examinations? A comparative analysis of different Large Language Models ’ accuracy and reliability in the 2022 In-Service Assessment of the European Board of Urology
ConclusionsThe performance of the tested LLMs in addressing urological specialist inquiries warrants further refinement. Moreover, the deficiency in response reliability contributes to existing challenges related to their current utility for educational purposes. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research

Trends in kidney transplantation and living donor nephrectomy in Germany: a total population analysis from 2006 to 2021
ConclusionsThere is an increasing trend toward minimal-invasive LDN in recent years. Overall, in-hospital mortality was low after KT. However, 5 deceased healthy donors after LKD caution that the risks of this procedure should also be taken very seriously. (Source: World Journal of Urology)
Source: World Journal of Urology - January 10, 2024 Category: Urology & Nephrology Source Type: research