Automated Measurement of Ovary Development in Atlantic Salmon Using Deep Learning
Salmon breeding companies control the egg stripping period through environmental change, which triggers the need to identify the state of maturation. Ultrasound imaging of the salmon ovary is a proven non-invasive tool for this purpose; however, the process is laborious, and the interpretation of the ultrasound scans is subjective. Real-time ultrasound image segmentation of Atlantic salmon ovary provides an opportunity to overcome these limitations. However, several application challenges need to be addressed to achieve this goal. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 8, 2024 Category: Radiology Authors: Yasin Yari, Ingun N æve, Asle Hammerdal, Per Helge Bergtun, Svein-Erik Måsøy, Marco Marien Voormolen, Lasse Lovstakken Tags: Original Contribution Source Type: research

Biopathologic Characterization and Grade Assessment of Breast Cancer With 3-D Multiparametric Ultrasound Combining Shear Wave Elastography and Backscatter Tensor Imaging
Despite recent improvements in medical imaging, the final diagnosis and biopathologic characterization of breast cancers currently still requires biopsies. Ultrasound is commonly used for clinical examination of breast masses. B-Mode and shear wave elastography (SWE) are already widely used to detect suspicious masses and differentiate benign lesions from cancers. But additional ultrasound modalities such as backscatter tensor imaging (BTI) could provide relevant biomarkers related to tissue organization. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 8, 2024 Category: Radiology Authors: Jean-Baptiste Guillaumin, Lounes Djerroudi, Jean-Fran çois Aubry, Anne Tardivon, Alexandre Dizeux, Mickaël Tanter, Anne Vincent-Salomon, Béatrice Berthon Tags: Original Contribution Source Type: research

Assessment of Basic Thoracic Ultrasound Skills in Immersive Virtual Reality: Gathering Validity Evidence
This study was aimed at developing an IVR test for assessing TUS skills, gathering validity evidence and establishing a pass/fail score. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 6, 2024 Category: Radiology Authors: Anders Bo Nielsen, Jonas Dragsb æk, Niels Jacobsen, Christian B. Laursen, Amy Farr, Marek Slavicky, Lars Konge, Pia Iben Pietersen Tags: Original Contribution Source Type: research

Safety Review of Therapeutic Ultrasound for Spinal Cord Neuromodulation and Blood –Spinal Cord Barrier Opening
New focused ultrasound spinal cord applications have emerged, particularly those improving therapeutic agent delivery to the spinal cord via blood –spinal cord barrier opening and the neuromodulation of spinal cord tracts. One hurdle in the development of these applications is safety. It may be possible to use safety trends from seminal and subsequent works in focused ultrasound to guide the development of safety guidelines for spinal cord a pplications. We collated data from decades of pre-clinical studies and illustrate a clear relationship between damage, time-averaged spatial peak intensity and exposure duration. (So...
Source: Ultrasound in Medicine and Biology - January 4, 2024 Category: Radiology Authors: Rui Xu, Bradley E. Treeby, Eleanor Martin Tags: Review Article Source Type: research

BPSegSys: A Brachial Plexus Nerve Trunk Segmentation System Using Deep Learning
Ultrasound-guided nerve block anesthesia (UGNB) is a high-tech visual nerve block anesthesia method that can be used to observe the target nerve and its surrounding structures, the puncture needle's advancement and local anesthetics spread in real time. The key in UGNB is nerve identification. With the help of deep learning methods, the automatic identification or segmentation of nerves can be realized, assisting doctors in completing nerve block anesthesia accurately and efficiently. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 4, 2024 Category: Radiology Authors: Yu Wang, Binbin Zhu, Lingsi Kong, Jianlin Wang, Bin Gao, Jianhua Wang, Dingcheng Tian, Yudong Yao Tags: Original Contribution Source Type: research

Reply to “Critique of a Study on Breast Ultrasound as an Adjunct to Breast Tomosynthesis for Breast Cancer Screening and Diagnosis”
We thank Bansal [1] for the interest and feedback we received on the article "Automated Breast Ultrasound Provides Comparable Diagnostic Performance in Opportunistic Screening and Diagnostic Assessment" published in Ultrasound in Medicine& Biology. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 3, 2024 Category: Radiology Authors: Kartini Rahmat, Nazimah Ab Mumin Tags: Letter to the Editor-in-Chief Source Type: research

3-D Contrast-Enhanced Fusion Ultrasound for Accurate Volume Assessment of Vessel Lumen and Plaque in Carotid Artery Disease as Compared With Computed Tomography Angiography
Three-dimensional contrast-enhanced fusion ultrasound (CEFUS) of atherosclerotic carotid arteries provides spatial visualization of the vessel lumen, creating a lumenography. As in 3-D computed tomography angiography (CTA), 3-D CEFUS outlines the contrast-filled lumen. Plaque and vessel contours are distinguished in 3-D CEFUS, allowing plaque volume quantification as a valid estimate of carotid plaque burden. Three-dimensional CEFUS is unproven in intermodality studies, vindicating the assessment of 3-D CEFUS applicability and comparing 3-D CEFUS and 3-D CTA lumenography as a proof-of-concept study. (Source: Ultrasound in ...
Source: Ultrasound in Medicine and Biology - January 3, 2024 Category: Radiology Authors: Karin Yeung, Jonas Peter Eiberg, Antoine Collet-Billon, Benjamin Vikj ær Sandholt, Majken Lyhne Jessen, Henrik Hegaard Sillesen, Nikolaj Eldrup Tags: Original Contribution Source Type: research

Direct Emulsification of Stable Superheated Perfluorobutane Nanodroplets by Sonication: Addressing the Limitations of the Microbubble Condensation Technique
We have previously determined that direct formulation of a phospholipid-based perfluorobutane (PFB) emulsion using high-pressure homogenization produces monodispersed PFB nanodroplets (NDs) with relatively few non-PFB-filled NDs. In this article, we describe a simpler strategy to reproducibly formulate highly concentrated superheated PFB NDs using a probe sonicator, a more widely available tool. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - January 3, 2024 Category: Radiology Authors: Adam Woodward, Robert F. Mattrey, Caroline de Gracia Lux Tags: Original Contribution Source Type: research

Corrigendum to ‘Molecular Identity Changes of Tumor-Associated Macrophages and Microglia After Magnetic Resonance Imaging–Guided Focused Ultrasound–Induced Blood–Brain Barrier Opening in a Mouse Glioblastoma Model’ [Ultrasound in Med & Biol. 49 (2023) 1082-1090]
The authors regret that the Acknowledgments in the article were incomplete. The full Acknowledgments are as follows: (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 30, 2023 Category: Radiology Authors: Yanrong Zhang, Jing Wang, Sara Natasha Ghobadi, Haiyan Zhou, Ai Huang, Marco Gerosa, Qingyi Hou, Olivier Keunen, Anna Golebiewska, Frezghi G. Habte, Gerald A. Grant, Ramasamy Paulmurugan, Kevin S. Lee, Max Wintermark Tags: Corrigendum Source Type: research

Development of an In Vitro Model to Study Mechanisms of Ultrasound-Targeted Microbubble Cavitation –Mediated Blood–Brain Barrier Opening
Ultrasound-targeted microbubble cavitation (UTMC)-mediated blood –brain barrier (BBB) opening is being explored as a method to increase drug delivery to the brain. This strategy has progressed to clinical trials for various neurological disorders, but the underlying cellular mechanisms are incompletely understood. In the study described here, a contact co-cultu re transwell model of the BBB was developed that can be used to determine the signaling cascade leading to increased BBB permeability. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 29, 2023 Category: Radiology Authors: Grace E. Conway, Anurag N. Paranjape, Xucai Chen, Flordeliza S. Villanueva Tags: Original Contribution Source Type: research

Development and Comparison of Prediction Models Based on Sonovue- and Sonazoid-Enhanced Ultrasound for Pathologic Grade and Microvascular Invasion in Hepatocellular Carcinoma
This study was aimed at developing and comparing prediction models based on Sonovue and Sonazoid contrast-enhanced ultrasound (CEUS) in predicting pathologic grade and microvascular invasion (MVI) of hepatocellular carcinoma (HCC). Also investigated was whether Kupffer phase images have additional predictive value for the above pathologic features. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 28, 2023 Category: Radiology Authors: Rui Zhang, Di Li, Yanlin Chen, Wenxin Xu, Wenwen Zhou, Manxia Lin, Xiaoyan Xie, Ming Xu Tags: Original Contribution Source Type: research

Automatic Max-Likelihood Envelope Detection Algorithm for Quantitative High-Frame-Rate Ultrasound for Neonatal Brain Monitoring
Post-operative brain injury in neonates may result from disturbed cerebral perfusion, but accurate peri-operative monitoring is lacking. High-frame-rate (HFR) cerebral ultrasound could visualize and quantify flow in all detectable vessels using spectral Doppler; however, automated quantification in small vessels is challenging because of low signal amplitude. We have developed an automatic envelope detection algorithm for HFR pulsed wave spectral Doppler signals, enabling neonatal brain quantitative parameter maps during and after surgery. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 23, 2023 Category: Radiology Authors: Anna J. Kortenbout, Sophie Costerus, Jeroen Dudink, Nico de Jong, Jurgen C. de Graaff, Hendrik J. Vos, Johan G. Bosch Tags: Original Contribution Source Type: research

Combined Assessment of 2-D Ultrasound and Real-Time Shear Wave Elastography of Low-Intensity Pulsed Ultrasound Therapy Efficacy in Rabbits with Achilles Tendinopathy
Low-intensity pulsed ultrasound (LIPUS) has been gradually used to treat Achilles tendinopathy. However, there are limited non-invasive and efficient instruments for monitoring LIPUS efficacy in Achilles tendinopathy. The purpose of this study was to assess the therapeutic effectiveness of LIPUS after Achilles tendinopathy by 2-D ultrasound and real-time shear wave elastography (SWE). (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 20, 2023 Category: Radiology Authors: Mengyao Liu, Qian Zheng, Yiwen Zheng, Yijing Yao, Rui Wang, Dean Ta, Lixin Jiang Tags: Original Contribution Source Type: research

Critique of a Study on Breast Ultrasound as an Adjunct to Breast Tomosynthesis for Breast Cancer Screening and Diagnosis
I am writing to provide critical feedback on the article by Rahmat et al. [1] published in Ultrasound in Medicine& Biology. The study is a welcome addition to the growing literature on automated breast ultrasound (ABUS) as an adjunct to digital breast tomosynthesis (DBT) for breast cancer screening and diagnosis. However, there are a few key limitations to the study that should be considered when interpreting the results. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 19, 2023 Category: Radiology Authors: Amit Bansal Tags: Letter to the Editor-in-Chief Source Type: research

Monitoring of Curve Progression in Patients with Adolescent Idiopathic Scoliosis Using 3-D Ultrasound
The aim of the work described here was to determine whether 3-D ultrasound can provide results comparable to those of conventional X-ray examination in assessing curve progression in patients with adolescent idiopathic scoliosis (AIS). (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - December 19, 2023 Category: Radiology Authors: Kelly Ka-Lee Lai, Timothy Tin-Yan Lee, Heidi Hin-Ting Lau, Winnie Chiu-Wing Chu, Jack Chun-Yiu Cheng, Ren é Marten Castelein, Tom P.C. Schlösser, Tsz-Ping Lam, Yong-Ping Zheng Tags: Original Contribution Source Type: research