Effect of goshajinkigan on the mechanical hypoesthesia of streptozotocin ‐induced diabetic peripheral neuropathy in mice
ConclusionHere, we found for the first time that GJG improves the mechanical hypoesthesia in the later stage of DPN. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 9, 2020 Category: Complementary Medicine Authors: Koki Inagaki, Yoshikazu Arai, Taishi Akasaki, Tami Yamada, Rui Tanaka, Shinsuke Hisaka, Mitsuhiko Nose Tags: ORIGINAL ARTICLE Source Type: research

Hochuekkito comprising Atractylodis lanceae rhizoma prevents pulmonary infection of Streptococcus pneumoniae in cyclophosphamide ‐treated mice through acceleration of anti‐bacterial protein production
ConclusionProphylactic treatment with ALR ‐hochuekkito formula protected immuno‐compromised mice from bacterial pneumonia by enhancing the production of anti‐bacterial proteins such as surfactant protein A/D and chitinase‐3‐like‐1 in the lung. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 9, 2020 Category: Complementary Medicine Authors: Satoshi Ideno, Yosuke Tanaka, Kayako Sasou, Haruna Hosaka, Hidenori Matsui, Hiroko Maruyama, Miki Tonooka, Mari Endo, Takayuki Nagai, Hiroyuki Seki, Toshihiko Hanawa, Go Ito, Hiroshi Odaguchi, Hiroshi Morisaki, Hiroaki Kiyohara Tags: ORIGINAL ARTICLE Source Type: research

Boiogito extract alters fecal bile acid profile in mice: Possible roles in changes in fecal and liver lipid levels
ConclusionOur data suggest that BOT extract might increase fecal cholesterol excretion and decrease hepatic lipid levels by decreasing the hydrophobicity and level of an FXR agonist in intestinal bile acids. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 9, 2020 Category: Complementary Medicine Authors: Zhuoer Chen, Shiro Watanabe, Yuto Nishidono, Ken Tanaka Tags: ORIGINAL ARTICLE Source Type: research

Assessing the efficacy of a tongue image analyzing system (TIAS) for the objective diagnosis of static blood: An observational, retrospective, single ‐center study of Japanese Kampo medicine
ConclusionTC diagnosis with TIAS would be a useful screening tool for judging the severity of SB. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 9, 2020 Category: Complementary Medicine Authors: Mosaburo Kainuma, Chiaki Matsumura, Takehiro Kawashiri, Daisuke Kobayashi, Aya Murakami, Toshiya Nakaguchi, Takao Namiki, Takao Shimazoe Tags: ORIGINAL ARTICLE Source Type: research

The active ingredients in the anti ‐obesity drug bofutsushosan in high‐fat‐diet‐fed obese mice
ConclusionGlycyrrhiza, rhubarb, gardenia, ephedra and mirabilite were the active components responsible for the effect of BTS. Glycyrrhizic acid and sennoside AB induced the early phase while geniposide and ephedrine hydrochloride induced the later phase of the anti ‐obesity activity of BTS. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 9, 2020 Category: Complementary Medicine Authors: Tatsuo Takahashi, Kenta Hori, Eri Yoshida, Yuri Ikeda ‐Matsuo, Tsutomu Shimada, Masaaki Nomura, Shinjiro Kobayashi Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
Traditional& Kampo Medicine, Volume 7, Issue 3, Page 113-114, December 2020. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 8, 2020 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research

Announcement
Traditional& Kampo Medicine, Volume 7, Issue 3, Page 186-186, December 2020. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 8, 2020 Category: Complementary Medicine Tags: ANNOUNCEMENT Source Type: research

Basic pharmacological mechanisms and clinical evidence of the efficacy of Hochuekkito against infectious diseases and its potential for use against COVID ‐19
ConclusionCODIV ‐19 is characterized by high risk for the aged and people with other disease complications, cytokine hyperactivity in the severe stage, and sequelae in the recovery stage. Considering the immune‐stimulative/modulative effects of HET on inflammatory conditions and against exhaustion and frailty, it may be useful for prevention, treatment, and recovery from COVID‐19. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 3, 2020 Category: Complementary Medicine Authors: Shin Takayama, Akiko Kikuchi, Toshiaki Makino, Mosaburo Kainuma, Takao Namiki, Takashi Ito Tags: REVIEW Source Type: research

Anti ‐inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae on mice
ConclusionOur data suggest the potential benefit of FBRA as a functional food to prevent excessive inflammation. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2020 Category: Complementary Medicine Authors: Lin Umeyama, Shiori Kasahara, Misa Sugawara, Satoru Yokoyama, Ikuo Saiki, Yoshihiro Hayakawa Tags: ORIGINAL ARTICLE Source Type: research

Anatomical factors influencing traditional abdominal examination in Kampo diagnosis: Analysis by computed tomography
ConclusionOur study demonstrates that abdominal aortic pulsation is anatomically associated with the depth of the artery. The supra ‐umbilical region appeared to be the most suitable location for evaluating abdominal aortic pulsation, as the aortic artery is shallowest at that point and is least influenced by the depth of the abdominal artery. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2020 Category: Complementary Medicine Authors: Hirobumi Shimada, Takao Namiki, Yoshiro Hirasaki, Takeshi Oji, Toshiya Nakaguchi, Keigo Ueda, Yuji Kasahara, Koichi Nagamine, Hideki Okamoto, Shuji Yakubo Tags: ORIGINAL ARTICLE Source Type: research

Effect of heat processing on the quality and alkaloid contents of Coptis Rhizome
ConclusionOur results suggest that black ‐colored chopped Oren pieces in the market are produced by excessive heating, which affects the quality of the medicine and its alkaloid content. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2020 Category: Complementary Medicine Authors: Shuichiro Akiba, Yoshiro Sahashi, Tadamichi Mitsuma Tags: ORIGINAL ARTICLE Source Type: research

Anatomical factors influencing traditional abdominal examination in Kampo diagnosis: Analysis by computed tomography
ConclusionOur study demonstrates that abdominal aortic pulsation is anatomically associated with the depth of the artery. The supra ‐umbilical region appeared to be the most suitable location for evaluating abdominal aortic pulsation, as the aortic artery is shallowest at that point and is least influenced by the depth of the abdominal artery. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2020 Category: Complementary Medicine Authors: Hirobumi Shimada, Takao Namiki, Yoshiro Hirasaki, Takeshi Oji, Toshiya Nakaguchi, Keigo Ueda, Yuji Kasahara, Koichi Nagamine, Hideki Okamoto, Shuji Yakubo Tags: ORIGINAL ARTICLE Source Type: research

Anti ‐inflammatory effect of fermented brown rice and rice bran with Aspergillus oryzae on mice
ConclusionOur data suggest the potential benefit of FBRA as a functional food to prevent excessive inflammation. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2020 Category: Complementary Medicine Authors: Lin Umeyama, Shiori Kasahara, Misa Sugawara, Satoru Yokoyama, Ikuo Saiki, Yoshihiro Hayakawa Tags: ORIGINAL ARTICLE Source Type: research