Investigation of Ogikenchuto (TJ ‐98) for intestinal fibrosis using a mouse model of dextran sulfate sodium‐induced colitis
ConclusionsThis study confirmed that TJ-98 suppressed the inflammation caused by DSS-induced enteritis and decreased the associated intestinal fibrosis, highlighting its potential as an inexpensive novel therapeutic agent for UC. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 8, 2023 Category: Complementary Medicine Authors: Shunsuke Watanabe,
Mikihiro Inoue,
Atsuki Naoe,
Mika Murayama Tags: ORIGINAL ARTICLE Source Type: research
Quantitative analyses of sennosides A and B in eight ethical bofutsushosan extract products
ConclusionIt is recommended that the quantities of sennosides A and B in Kampo extract products, including Rhubarb, be described in the package insert. When preparing Rhubarb-containing Kampo medicines, sennosides A and B decomposition can be ignored for decoction times of up to 60 min. Further studies on the biological activity of secondary metabolites other than sennosides A and B are necessary for Rhubarb quality control. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 5, 2023 Category: Complementary Medicine Authors: Takashi Shii,
Tomoki Iguchi,
Minpei Kuroda,
Tamami Shimazaki,
Ryuichiro Suzuki,
Yoshihiro Mimaki Tags: ORIGINAL ARTICLE Source Type: research
Effect of Majoon ‐e‐Nisyan (a traditional polyherbal Unani formulation) in animal models of learning and memory
ConclusionThe study indicated thatmajoon-e-nisyan had a beneficial effect on cognitive functions at tested dose levels of 1000 and 1500 mg/kg bw in both models. However, the dose of 500 mg/kg bw was ineffective. The current study was successful in demonstrating the effectiveness ofmajoon-e-nisyan using two validated mouse models. Our findings provide more evidence in favor of the concept of hot-tempered medications used in traditional Unani medicine to treat dementia. This formulation may be used as an alternative to conventional dementia medications. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2023 Category: Complementary Medicine Authors: Masud Shaikh,
Mohd Urooj,
Uzma Viquar,
Ghazala Javed,
Munawwar Husain Kazmi,
Gulam Mohammed Husain Tags: ORIGINAL ARTICLE Source Type: research
Late gastroenterological complications in children after allogeneic hematopoietic stem cell transplantation: A retrospective cohort study and a case series of children treated with Kampo medicines
ConclusionsLate GI complications may be a burden on children after allo-HSCT. Kampo medicines may provide a safe and promising therapy to resolve GI symptoms not otherwise specified. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - November 21, 2023 Category: Complementary Medicine Authors: Nozomu Kawashima,
Shinsuke Kataoka,
Motoharu Hamada,
Eri Nishikawa,
Rieko Taniguchi,
Atsushi Narita,
Hideki Muramatsu,
Nobuhiro Nishio,
Yoshiyuki Takahashi Tags: SPECIAL REPORT Source Type: research
Review of frequently used Kampo prescriptions: Part 4, Ninjin'yoeito
ConclusionRecently, NYT has been widely used to treat several symptoms and conditions under the National Health Insurance System of Japan. Clinical studies showed the efficacy of NYT to treat anemia, frailty, cognitive dysfunction, anorexia, apathy, and fatigue/malaise, as well as for long-term cancer treatment support. The pharmacological mechanisms supporting its effects are also being reported. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 8, 2023 Category: Complementary Medicine Authors: Shin Takayama,
Seiwa Michihara,
Yoko Kimura,
Akinori Morinaga,
Kyohei Miyakawa,
Nobuhiko Tsushima,
Kahori Otani,
Atsuko Jinnai,
Yuko Aso,
Asako Okabayashi,
Ryutaro Arita,
Tatsuya Nogami,
Akio Inui Tags: REVIEW Source Type: research
Three cases successfully treated with a combination of unkeito and boiogito for menopausal arthralgia
(Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 4, 2023 Category: Complementary Medicine Authors: Daigo Taniguchi,
Tatsuya Nogami,
Noriko Miyatake,
Toko Tsuruta,
Makoto Arai Tags: LETTER TO THE EDITOR Source Type: research
Safety evaluation of continuous administration of a high dose of Valeriana fauriei root extract in mice and in humans through an open ‐label study
ConclusionSince there was little change in the experimental values at continuous high doses of VF at 10 g/day, it can be concluded that approximately one-fifth of this dose (2 g VF/day) is less harmful. However, daytime sleepiness should be considered. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 3, 2023 Category: Complementary Medicine Authors: Misato Ota,
Yuki Oiwa,
Yasuhito Maki,
Ichiro Utaka,
Sachie Arima,
Yoichi Matsuo,
Toshiaki Makino,
Shunsuke Nojiri Tags: ORIGINAL ARTICLE Source Type: research
Preventive effect of a traditional Japanese Kampo medicine, shakuyakukanzoto, against neurotoxicity of FOLFOX plus bevacizumab used for metastatic colorectal cancer management: A single ‐arm phase II study
ConclusionShakuyakukanzoto substantially reduced oxaliplatin-induced neurotoxicity without negatively affecting tumor response or survival in FOLFOX + BV-treated patients with CRC. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - September 27, 2023 Category: Complementary Medicine Authors: Hiroaki Takagi,
Shinya Kajiura,
Ayumu Hosokawa,
Naoki Horikawa,
Itsuro Terada,
Taishi Hata,
Yuka Kobayashi,
Yuji Tsukioka,
Kazuhisa Yabushita,
Takashi Matsuo,
Hiroki Yoshita,
Akira Ueda,
Kohei Ogawa,
Takayuki Ando,
Ryuji Hayashi,
Ichiro Yas Tags: ORIGINAL ARTICLE Source Type: research
A review of frequently used Kampo prescriptions. Part 3. Yokukansan
ConclusionYKS is useful for BPSD and perioperative mental instability. The modulation of the serotonergic and glutamatergic neural pathways is one of mechanisms. Pseudoaldosteronism is one of the side effects. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - September 27, 2023 Category: Complementary Medicine Authors: Hideaki Yamaguchi,
Tetsuhiro Yoshino,
Hiroaki Oizumi,
Ryutaro Arita,
Tatsuya Nogami,
Shin Takayama Tags: REVIEW Source Type: research
Sasa veitchii extract alleviates nonalcoholic steatohepatitis in methionine –choline deficient diet‐induced mice by regulating peroxisome proliferator‐activated receptor alpha
ConclusionOur results showed that SE protected mice against MCD-induced hepatic injury, including oxidative stress and inflammation, by modulating peroxisome proliferator-activated receptor alpha activation. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - August 23, 2023 Category: Complementary Medicine Authors: Hiroki Yoshioka,
Sixun Wu,
Takeshi Moriishi,
Yosuke Tsukiboshi,
Satoshi Yokota,
Nobuhiko Miura,
Masae Yoshikawa,
Naoki Inagaki,
Yuki Matsushita,
Makoto Nakao Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - August 18, 2023 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research
Effectiveness of keigairengyoto in patients with chronic rhinosinusitis after endoscopic sinus surgery
ConclusionKRT appears to be a promising agent for the regulation of bacterial growth during postoperative treatment for chronic sinusitis. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - August 2, 2023 Category: Complementary Medicine Authors: Hidetaka Ikemiyagi,
Hiromitsu Hatakeyama,
Yasuhiro Isono,
Tatsu Kuwahara,
Yamato Oki,
Hiroaki Ninomiya,
Ayaka Yaguchi,
Kenta Fukui,
Nobuhiko Oridate Tags: ORIGINAL ARTICLE Source Type: research
Evaluation of capsules containing Valeriana fauriei root extract for sleep improvement: A randomized, double ‐blind, placebo‐controlled, cross‐over comparative trial
ConclusionWe clinically determined that VF, a folk medicine, improves sleep onset and sleep quality in people with suspected insomnia without serious adverse events at the dosage of 2 g VF/day. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 13, 2023 Category: Complementary Medicine Authors: Misato Ota,
Yuki Oiwa,
Yasuhito Maki,
Ichiro Utaka,
Sachie Arima,
Yoichi Matsuo,
Toshiaki Makino,
Shunsuke Nojiri Tags: ORIGINAL ARTICLE Source Type: research
Two cases of muscle cramp successfully treated with shichimotsukokato
(Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 12, 2023 Category: Complementary Medicine Authors: Tetsuro Oikawa,
Yoshihide Yakazu,
Kazuhiro Hirasawa,
Yoshiko Yamaguchi,
Yoshimi Harada Tags: LETTER TO THE EDITOR Source Type: research
Overview of diagnostic laboratory tests and diagnostic criteria for liver injury caused by Kampo medicine
ConclusionThe diagnosis of KMILI remains challenging, and we eagerly await the development of reliable biomarkers for KMILI. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 7, 2023 Category: Complementary Medicine Authors: Naoki Mantani Tags: REVIEW Source Type: research
