Can Biologic Aggressiveness and Metastatic Potential of Primary Lung Cancer Be Predicted from Clinical Staging Alone?
The future biologic aggressiveness and metastatic potential of lung cancer, as in other cancers, cannot be predetermined from the current clinical information, imaging studies, and pathologic examination whose purpose is to provide diagnosis and mutation studies and molecular drivers only in making decision for treatment. There is a need for better understanding of the biologic characteristics and aggressiveness of lung cancer. The most that is achieved from clinical staging and pathologic staging is in the planning of treatment of lung cancer and predicting prognosis. Aggressive biologic behavior to come is not within the...
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Farid M. Shamji, Gilles Beauchamp Source Type: research

Is Small Cell Lung Cancer a Surgical Disease at the Present Time?
Small cell lung cancer is an aggressive form of cancer. Previously, surgery was rarely considered because most patients present at the advanced stages of the disease. New research and the advances in medical imaging has challenged this notion proving that, as part of a multimodal treatment pathway, surgery has a key role to play in the management of patients with early small cell lung cancer. In this chapter, we present the most pertinent research that has shaped clinical practice and outline the current treatment algorithm for small cell lung cancer. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Avgi Loizidou, Eric Lim Source Type: research

Assessment and Rehabilitation of the Compromised Patient Prior to Thoracotomy
This article develops a schematic for a logical progression through the assessment of prethoracotomy patients in order that those facing a significant surgical risk might undergo pulmonary rehabilitation to improve exercise performance followed by reassessment prior to surgery. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Thomas Richard James Todd Source Type: research

Ethics for Thoracic Surgeons in the Management of Lung Cancer
Lung cancer is a terrible disease, with less than 20% of patients with a diagnosis of lung cancer able to have a resection but many relapsing, making it one of the most biologically aggressive cancers known. Thoracic surgeons do not see all the other 80% but are often consulted and have to make recommendations, and sometimes have to intervene. Thoracic surgeons should be well informed about the ethical framework and participate actively in the discussion. Ethics is an important aspect of surgical practice and has implications for patients, surgeons, and surgical teams, as well as for society. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Gilles Beauchamp, Farid M. Shamji Source Type: research

Guiding Principles in the Management of Synchronous and Metachronous Primary Non –Small Cell Lung Cancer
Multiple lung cancers can be found simultaneously, with incidence ranging from 1% to 8%. Documentation of more than 1 pulmonary lesion can be challenging, because these solid, ground-glass, or mixed-density tumors may represent multicentric malignant disease or intrapulmonary metastases. If mediastinal nodal and distant deposits are excluded, surgery should be contemplated. After surgical treatment of lung cancer, patients should be followed closely for an undetermined period of time. Good clinical judgment is of outmost importance in deciding which individuals will benefit from those surgical interventions and which are c...
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Jocelyn Gregoire Source Type: research

Recent Advances in Small Cell and Non –Small Cell Lung Cancer, Diagnosis, Staging, and Surgical Treatment: A Tribute to Jean Deslauriers
On September 13, 2019, the thoracic surgical community lost a valued member when Dr Jean Deslauriers died after 40 years of practice, of the very disease that he spent lifetime studying and treating. He was regarded as a leader in the field of thoracic oncology and had a profound impact on the surgical teaching, clinical research, writing of scientific papers on lung cancer, career, and life of many of the authors of this 2-part issue on lung cancer. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Farid M. Shamji, Gilles Beauchamp Tags: Preface Source Type: research

Tribute and Dedication for Dr Jean Deslauriers (1945-2019)
On September 13, 2019, the thoracic surgical community lost a valued member when Dr Jean Deslauriers died of the very disease that he spent a lifetime studying and practicing.1 He was a leader in the field of thoracic oncology and lung cancer and had a profound impact on the career and life of many of the authors of this 2-part issue on lung cancer. Indeed, most articles are written by renowned thoracic surgeons and medical oncologists who were friends or trainees of Dr Jean Deslauriers and possess detailed knowledge of the disease and comprehend it. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Farid M. Shamji, Gilles Beauchamp Tags: Dedication Source Type: research

Lung Cancer 2021, Part I
THORACIC SURGERY CLINICS (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Farid M. Shamji, Gilles Beauchamp Source Type: research

Copyright
ELSEVIER (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

Contributors
VIRGINIA R. LITLE, MD (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

Contents
Farid M. Shamji and Gilles Beauchamp (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

Thoracic Surgery Clinics
Lung Cancer 2021, Part II (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - July 23, 2021 Category: Cardiovascular & Thoracic Surgery Source Type: research

Embolotherapy in Bronchial Hemorrhage
Hemoptysis, defined as bleeding into the tracheobronchial tree, is a serious symptom that can cause asphyxiation if inadequately treated. Massive hemoptysis carries a very high mortality risk, and therefore, a prompt multidisciplinary approach to hemoptysis is highly encouraged. Bronchial artery embolization has evolved as the mainstay of treatment in control of hemoptysis. It is a low-risk procedure that carries high initial clinical success rates. Despite relatively high recurrence rates, it can be repeated until the underlying disease process can be definitively treated. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - June 10, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Ashish Gupta, Adnan Hadziomerovic Source Type: research

Role of the Thoracic Radiologist in the Evaluation and Management of Solid and Subsolid Lung Nodules
In this review, the authors describe the imaging characteristics of solid and subsolid nodules as well as their management recommendations including the use of image-guided percutaneous biopsy and preoperative coil localization. Using case presentations, they offer practical management tips for the most commonly encountered nodule nodules in a thoracic surgical practice. (Source: Thoracic Surgery Clinics)
Source: Thoracic Surgery Clinics - June 8, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Carole Dennie, Hamid Bayanati, Carolina A. Souza, Rebecca Peterson, Farid Shamji Source Type: research

Management of Air Leaks and Residual Spaces Following Lung Resection
Air leaks and residual airspaces following lung resection are common problems in thoracic surgery. Prolonged air leaks frequently necessitate extended hospitalization. This is true whether the surgery was done in an open fashion or with video-/robot-assisted thoracic surgery. In this review, the authors present common risk factors that predispose to prolonged air leaks and discuss the management options for air leaks by focusing on intraoperative maneuvers, postoperative considerations, and options for difficult-to-manage air leaks and spaces. They also discuss options to prevent such spaces and present management approach...
Source: Thoracic Surgery Clinics - June 8, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Antonia Kreso, Douglas J. Mathisen Source Type: research