Thomas S. Kuhn: key to a better understanding of the extended evolutionary synthesis
Theory Biosci. 2023 Nov 17. doi: 10.1007/s12064-023-00409-w. Online ahead of print.ABSTRACTIn recent years, some scholars have explicitly questioned the desirability or utility of applying the classical and "old-fashioned" theories of scientific change by the likes of Karl Popper and Thomas S. Kuhn to the question of the precise nature and significance of the extended evolutionary synthesis (EES). Supposedly, these twentieth-century philosophers are completely irrelevant for a better understanding of this new theoretical framework for the study of evolution. Here, it will be argued that the EES can be fruitfully interprete...
Source: Theory in Biosciences - November 17, 2023 Category: Biology Authors: Koen B Tanghe Source Type: research
Thomas S. Kuhn: key to a better understanding of the extended evolutionary synthesis
Theory Biosci. 2023 Nov 17. doi: 10.1007/s12064-023-00409-w. Online ahead of print.ABSTRACTIn recent years, some scholars have explicitly questioned the desirability or utility of applying the classical and "old-fashioned" theories of scientific change by the likes of Karl Popper and Thomas S. Kuhn to the question of the precise nature and significance of the extended evolutionary synthesis (EES). Supposedly, these twentieth-century philosophers are completely irrelevant for a better understanding of this new theoretical framework for the study of evolution. Here, it will be argued that the EES can be fruitfully interprete...
Source: Theory in Biosciences - November 17, 2023 Category: Biology Authors: Koen B Tanghe Source Type: research
Thomas S. Kuhn: key to a better understanding of the extended evolutionary synthesis
Theory Biosci. 2023 Nov 17. doi: 10.1007/s12064-023-00409-w. Online ahead of print.ABSTRACTIn recent years, some scholars have explicitly questioned the desirability or utility of applying the classical and "old-fashioned" theories of scientific change by the likes of Karl Popper and Thomas S. Kuhn to the question of the precise nature and significance of the extended evolutionary synthesis (EES). Supposedly, these twentieth-century philosophers are completely irrelevant for a better understanding of this new theoretical framework for the study of evolution. Here, it will be argued that the EES can be fruitfully interprete...
Source: Theory in Biosciences - November 17, 2023 Category: Biology Authors: Koen B Tanghe Source Type: research
Thomas S. Kuhn: key to a better understanding of the extended evolutionary synthesis
Theory Biosci. 2023 Nov 17. doi: 10.1007/s12064-023-00409-w. Online ahead of print.ABSTRACTIn recent years, some scholars have explicitly questioned the desirability or utility of applying the classical and "old-fashioned" theories of scientific change by the likes of Karl Popper and Thomas S. Kuhn to the question of the precise nature and significance of the extended evolutionary synthesis (EES). Supposedly, these twentieth-century philosophers are completely irrelevant for a better understanding of this new theoretical framework for the study of evolution. Here, it will be argued that the EES can be fruitfully interprete...
Source: Theory in Biosciences - November 17, 2023 Category: Biology Authors: Koen B Tanghe Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
Normalizing need not be the norm: count-based math for analyzing single-cell data
Theory Biosci. 2023 Nov 10. doi: 10.1007/s12064-023-00408-x. Online ahead of print.ABSTRACTCounting transcripts of mRNA are a key method of observation in modern biology. With advances in counting transcripts in single cells (single-cell RNA sequencing or scRNA-seq), these data are routinely used to identify cells by their transcriptional profile, and to identify genes with differential cellular expression. Because the total number of transcripts counted per cell can vary for technical reasons, the first step of many commonly used scRNA-seq workflows is to normalize by sequencing depth, transforming counts into proportiona...
Source: Theory in Biosciences - November 10, 2023 Category: Biology Authors: Samuel H Church Jasmine L Mah G ünter Wagner Casey W Dunn Source Type: research
On a population model with density dependence and Allee effect
Theory Biosci. 2023 Nov;142(4):423-441. doi: 10.1007/s12064-023-00407-y. Epub 2023 Oct 2.ABSTRACTWe study the dynamics of a discrete model with two different stages of the population, the pre-adult stage governed by a Beverton-Holt-type map and the adult stage by a [Formula: see text]-Ricker map. The composition of both maps gives the dynamics. The existence of the Allee effect is easily observed. We check that the model can evolve from a sure extinction to complicated dynamics. The presence of an almost sure extinction is proved to exist when the dynamical complexity is the highest possible.PMID:37783964 | DOI:10.1007/s12...
Source: Theory in Biosciences - October 2, 2023 Category: Biology Authors: J S C ánovas M Mu ñoz-Guillermo Source Type: research
On a population model with density dependence and Allee effect
Theory Biosci. 2023 Nov;142(4):423-441. doi: 10.1007/s12064-023-00407-y. Epub 2023 Oct 2.ABSTRACTWe study the dynamics of a discrete model with two different stages of the population, the pre-adult stage governed by a Beverton-Holt-type map and the adult stage by a [Formula: see text]-Ricker map. The composition of both maps gives the dynamics. The existence of the Allee effect is easily observed. We check that the model can evolve from a sure extinction to complicated dynamics. The presence of an almost sure extinction is proved to exist when the dynamical complexity is the highest possible.PMID:37783964 | DOI:10.1007/s12...
Source: Theory in Biosciences - October 2, 2023 Category: Biology Authors: J S C ánovas M Mu ñoz-Guillermo Source Type: research
On a population model with density dependence and Allee effect
Theory Biosci. 2023 Nov;142(4):423-441. doi: 10.1007/s12064-023-00407-y. Epub 2023 Oct 2.ABSTRACTWe study the dynamics of a discrete model with two different stages of the population, the pre-adult stage governed by a Beverton-Holt-type map and the adult stage by a [Formula: see text]-Ricker map. The composition of both maps gives the dynamics. The existence of the Allee effect is easily observed. We check that the model can evolve from a sure extinction to complicated dynamics. The presence of an almost sure extinction is proved to exist when the dynamical complexity is the highest possible.PMID:37783964 | DOI:10.1007/s12...
Source: Theory in Biosciences - October 2, 2023 Category: Biology Authors: J S C ánovas M Mu ñoz-Guillermo Source Type: research
On a population model with density dependence and Allee effect
Theory Biosci. 2023 Nov;142(4):423-441. doi: 10.1007/s12064-023-00407-y. Epub 2023 Oct 2.ABSTRACTWe study the dynamics of a discrete model with two different stages of the population, the pre-adult stage governed by a Beverton-Holt-type map and the adult stage by a [Formula: see text]-Ricker map. The composition of both maps gives the dynamics. The existence of the Allee effect is easily observed. We check that the model can evolve from a sure extinction to complicated dynamics. The presence of an almost sure extinction is proved to exist when the dynamical complexity is the highest possible.PMID:37783964 | DOI:10.1007/s12...
Source: Theory in Biosciences - October 2, 2023 Category: Biology Authors: J S C ánovas M Mu ñoz-Guillermo Source Type: research
