Stability of a diffusive-delayed HCV infection model with general cell-to-cell incidence function incorporating immune response and cell proliferation
Theory Biosci. 2023 Jul 12. doi: 10.1007/s12064-023-00395-z. Online ahead of print.ABSTRACTIn this work, we analyse the dynamics of a five-dimensional hepatitis C virus infection mathematical model including the spatial mobility of hepatitis C virus particles, the transmission of hepatitis C virus infection by mitosis process of infected hepatocytes with logistic growth, time delays, antibody response and cytotoxic T lymphocyte (CTL) immune response with general incidence functions for both modes of infection transmission, namely virus-to-cell as well as cell-to-cell. Firstly, we prove rigorously the existence, the uniquen...
Source: Theory in Biosciences - July 12, 2023 Category: Biology Authors: Alexis Nangue Yanick Junior Tchuimeni Source Type: research

Stability of a diffusive-delayed HCV infection model with general cell-to-cell incidence function incorporating immune response and cell proliferation
Theory Biosci. 2023 Jul 12. doi: 10.1007/s12064-023-00395-z. Online ahead of print.ABSTRACTIn this work, we analyse the dynamics of a five-dimensional hepatitis C virus infection mathematical model including the spatial mobility of hepatitis C virus particles, the transmission of hepatitis C virus infection by mitosis process of infected hepatocytes with logistic growth, time delays, antibody response and cytotoxic T lymphocyte (CTL) immune response with general incidence functions for both modes of infection transmission, namely virus-to-cell as well as cell-to-cell. Firstly, we prove rigorously the existence, the uniquen...
Source: Theory in Biosciences - July 12, 2023 Category: Biology Authors: Alexis Nangue Yanick Junior Tchuimeni Source Type: research

Growth modeling approach with the Verhulst coexistence dynamic properties for regulation purposes
Theory Biosci. 2023 Jul 8. doi: 10.1007/s12064-023-00397-x. Online ahead of print.ABSTRACTFor this research, the properties of the logistic growth model for independent and coexisting species were used to set definitions for the possible regulation of one or two growth variables through their coupling parameters. The present analysis is done for the single-species Verhulst model without coupling, the single-species Verhulst model coupled with an exogenous signal, and the two-species Verhulst coexistence growth model which represents six different ecological regimes of interaction. The models' parameters, such as the intrin...
Source: Theory in Biosciences - July 8, 2023 Category: Biology Authors: A J Morales-Erosa J Reyes-Reyes C M Astorga-Zaragoza G L Osorio-Gordillo C D Garc ía-Beltrán G Madrigal-Espinosa Source Type: research

Growth modeling approach with the Verhulst coexistence dynamic properties for regulation purposes
Theory Biosci. 2023 Jul 8. doi: 10.1007/s12064-023-00397-x. Online ahead of print.ABSTRACTFor this research, the properties of the logistic growth model for independent and coexisting species were used to set definitions for the possible regulation of one or two growth variables through their coupling parameters. The present analysis is done for the single-species Verhulst model without coupling, the single-species Verhulst model coupled with an exogenous signal, and the two-species Verhulst coexistence growth model which represents six different ecological regimes of interaction. The models' parameters, such as the intrin...
Source: Theory in Biosciences - July 8, 2023 Category: Biology Authors: A J Morales-Erosa J Reyes-Reyes C M Astorga-Zaragoza G L Osorio-Gordillo C D Garc ía-Beltrán G Madrigal-Espinosa Source Type: research

Growth modeling approach with the Verhulst coexistence dynamic properties for regulation purposes
Theory Biosci. 2023 Jul 8. doi: 10.1007/s12064-023-00397-x. Online ahead of print.ABSTRACTFor this research, the properties of the logistic growth model for independent and coexisting species were used to set definitions for the possible regulation of one or two growth variables through their coupling parameters. The present analysis is done for the single-species Verhulst model without coupling, the single-species Verhulst model coupled with an exogenous signal, and the two-species Verhulst coexistence growth model which represents six different ecological regimes of interaction. The models' parameters, such as the intrin...
Source: Theory in Biosciences - July 8, 2023 Category: Biology Authors: A J Morales-Erosa J Reyes-Reyes C M Astorga-Zaragoza G L Osorio-Gordillo C D Garc ía-Beltrán G Madrigal-Espinosa Source Type: research

Self-similarity and the maximum entropy principle in the genetic code
Theory Biosci. 2023 Jul 4. doi: 10.1007/s12064-023-00396-y. Online ahead of print.ABSTRACTThis paper addresses the relationship between information and structure of the genetic code. The code has two puzzling anomalies: First, when viewed as 64 sub-cubes of a [Formula: see text] cube, the codons for serine (S) are not contiguous, and there are amino acid codons with zero redundancy, which goes counter to the objective of error correction. To make sense of this, the paper shows that the genetic code must be viewed not only on stereochemical, co-evolution, and error-correction considerations, but also on two additional facto...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Subhash Kak Source Type: research

Symmetrical distributions of aminoacyl-tRNA synthetases during the evolution of the genetic code
Theory Biosci. 2023 Jul 5. doi: 10.1007/s12064-023-00394-0. Online ahead of print.ABSTRACTIn this work, we formulate the following question: How the distribution of aminoacyl-tRNA synthetases (aaRSs) went from an ancestral bidirectional gene (mirror symmetry) to the symmetrical distribution of aaRSs in a six-dimensional hypercube of the Standard Genetic Code (SGC)? We assume a primeval RNY code, two Extended Genetic RNA codes type 1 and 2, and the SGC. We outline the types of symmetries of the distribution of aaRSs in each code. The symmetry groups of aaRSs in each code are described, until the symmetries of the SGC displa...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Marco V Jos é Juan R Bobadilla Gabriel S Zamudio S ávio Torres de Farías Source Type: research

Self-similarity and the maximum entropy principle in the genetic code
Theory Biosci. 2023 Jul 4. doi: 10.1007/s12064-023-00396-y. Online ahead of print.ABSTRACTThis paper addresses the relationship between information and structure of the genetic code. The code has two puzzling anomalies: First, when viewed as 64 sub-cubes of a [Formula: see text] cube, the codons for serine (S) are not contiguous, and there are amino acid codons with zero redundancy, which goes counter to the objective of error correction. To make sense of this, the paper shows that the genetic code must be viewed not only on stereochemical, co-evolution, and error-correction considerations, but also on two additional facto...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Subhash Kak Source Type: research

Symmetrical distributions of aminoacyl-tRNA synthetases during the evolution of the genetic code
Theory Biosci. 2023 Jul 5. doi: 10.1007/s12064-023-00394-0. Online ahead of print.ABSTRACTIn this work, we formulate the following question: How the distribution of aminoacyl-tRNA synthetases (aaRSs) went from an ancestral bidirectional gene (mirror symmetry) to the symmetrical distribution of aaRSs in a six-dimensional hypercube of the Standard Genetic Code (SGC)? We assume a primeval RNY code, two Extended Genetic RNA codes type 1 and 2, and the SGC. We outline the types of symmetries of the distribution of aaRSs in each code. The symmetry groups of aaRSs in each code are described, until the symmetries of the SGC displa...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Marco V Jos é Juan R Bobadilla Gabriel S Zamudio S ávio Torres de Farías Source Type: research

Self-similarity and the maximum entropy principle in the genetic code
Theory Biosci. 2023 Jul 4. doi: 10.1007/s12064-023-00396-y. Online ahead of print.ABSTRACTThis paper addresses the relationship between information and structure of the genetic code. The code has two puzzling anomalies: First, when viewed as 64 sub-cubes of a [Formula: see text] cube, the codons for serine (S) are not contiguous, and there are amino acid codons with zero redundancy, which goes counter to the objective of error correction. To make sense of this, the paper shows that the genetic code must be viewed not only on stereochemical, co-evolution, and error-correction considerations, but also on two additional facto...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Subhash Kak Source Type: research

Symmetrical distributions of aminoacyl-tRNA synthetases during the evolution of the genetic code
Theory Biosci. 2023 Jul 5. doi: 10.1007/s12064-023-00394-0. Online ahead of print.ABSTRACTIn this work, we formulate the following question: How the distribution of aminoacyl-tRNA synthetases (aaRSs) went from an ancestral bidirectional gene (mirror symmetry) to the symmetrical distribution of aaRSs in a six-dimensional hypercube of the Standard Genetic Code (SGC)? We assume a primeval RNY code, two Extended Genetic RNA codes type 1 and 2, and the SGC. We outline the types of symmetries of the distribution of aaRSs in each code. The symmetry groups of aaRSs in each code are described, until the symmetries of the SGC displa...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Marco V Jos é Juan R Bobadilla Gabriel S Zamudio S ávio Torres de Farías Source Type: research

Self-similarity and the maximum entropy principle in the genetic code
Theory Biosci. 2023 Jul 4. doi: 10.1007/s12064-023-00396-y. Online ahead of print.ABSTRACTThis paper addresses the relationship between information and structure of the genetic code. The code has two puzzling anomalies: First, when viewed as 64 sub-cubes of a [Formula: see text] cube, the codons for serine (S) are not contiguous, and there are amino acid codons with zero redundancy, which goes counter to the objective of error correction. To make sense of this, the paper shows that the genetic code must be viewed not only on stereochemical, co-evolution, and error-correction considerations, but also on two additional facto...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Subhash Kak Source Type: research

Symmetrical distributions of aminoacyl-tRNA synthetases during the evolution of the genetic code
Theory Biosci. 2023 Jul 5. doi: 10.1007/s12064-023-00394-0. Online ahead of print.ABSTRACTIn this work, we formulate the following question: How the distribution of aminoacyl-tRNA synthetases (aaRSs) went from an ancestral bidirectional gene (mirror symmetry) to the symmetrical distribution of aaRSs in a six-dimensional hypercube of the Standard Genetic Code (SGC)? We assume a primeval RNY code, two Extended Genetic RNA codes type 1 and 2, and the SGC. We outline the types of symmetries of the distribution of aaRSs in each code. The symmetry groups of aaRSs in each code are described, until the symmetries of the SGC displa...
Source: Theory in Biosciences - July 4, 2023 Category: Biology Authors: Marco V Jos é Juan R Bobadilla Gabriel S Zamudio S ávio Torres de Farías Source Type: research

Kin term mimicry hypothesis
Theory Biosci. 2023 Jun 5. doi: 10.1007/s12064-023-00393-1. Online ahead of print.ABSTRACTAdaptive mimicry in animals is a well-known phenomenon. Here, we propose that a similarly adaptive strategy in humans is using kin terms for people who are not closely genetically related. Irrespective of the initiator attributing a kin term to a non-kin, we call this kin term mimicry (KTM). The emergence of human sociality and language allowed not only easy kin recognition, but also led to strong positive emotions related to such kin names as "mother," "father," "brother," "sister," "aunt" or "uncle." Although the phenomenon of using...
Source: Theory in Biosciences - June 5, 2023 Category: Biology Authors: Bogus ław Pawłowski Anna Chmieli ńska Source Type: research

Kin term mimicry hypothesis
Theory Biosci. 2023 Jun 5. doi: 10.1007/s12064-023-00393-1. Online ahead of print.ABSTRACTAdaptive mimicry in animals is a well-known phenomenon. Here, we propose that a similarly adaptive strategy in humans is using kin terms for people who are not closely genetically related. Irrespective of the initiator attributing a kin term to a non-kin, we call this kin term mimicry (KTM). The emergence of human sociality and language allowed not only easy kin recognition, but also led to strong positive emotions related to such kin names as "mother," "father," "brother," "sister," "aunt" or "uncle." Although the phenomenon of using...
Source: Theory in Biosciences - June 5, 2023 Category: Biology Authors: Bogus ław Pawłowski Anna Chmieli ńska Source Type: research