The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
Addressing the Threat of Emerging Viral Infections
Keio J Med. 2023;72(1):27. doi: 10.2302/kjm.ABSTRACT_72_1-2.ABSTRACTEmerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host responses to emerging viruses, including influenza virus, Ebola virus, and SARS-CoV-2, and using the knowledge gained from these studies to develop antivirals and vaccines.Influenza viruses cause epidemics every winter, but occasionally new influenza viruses emerge and spread worldwide (pandemic). We established a technique ...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Yoshihiro Kawaoka Source Type: research
The Unlikely Development of CAR T Cells: a Brief History and Prospects for the Future
Keio J Med. 2023;72(1):26. doi: 10.2302/kjm.ABSTRACT_72_1-1.ABSTRACTThe quest to cure cancer has been one of the Holy Grails of medicine. The discovery I am going to share with you, CAR T cells, is a promising new form of therapy of cancer that offers the prospect of curing cancer using the immune system. CAR T cells are the first form of synthetic biology to enter the practice of medicine. The notion of using the immune system to fight cancer is an old idea. Over a century ago, bacteria were ground up and injected into patients with late-stage cancers, and occasionally the cancer would disappear. However, we now have prec...
Source: The Keio Journal of Medicine - March 26, 2023 Category: Universities & Medical Training Authors: Carl H June Source Type: research
