Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Senso-immunology: The Emerging Connection between Pain and Immunity
Keio J Med. 2023 Jul 15. doi: 10.2302/kjm.2022-0037-IR. Online ahead of print.ABSTRACTThe sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune systems and have found that inflammation and bone destruction caused by fungal infection are suppressed by nociceptors. Furthermore, we have elucidated the molecular mechanism whereby fungal receptors are expressed on nociceptors and skin epithelium, how they cooperate to generate fungal pain, and how ...
Source: The Keio Journal of Medicine - July 17, 2023 Category: Universities & Medical Training Authors: Kenta Maruyama Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
Molecular Basis of Hereditary Hair Diseases
Keio J Med. 2023 Jul 4. doi: 10.2302/kjm.2023-0007-IR. Online ahead of print.ABSTRACTThe hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditary hair diseases in humans. Hereditary hair diseases are classified into non-syndromic and syndromic forms. In the Japanese population, the non-syndromic form of autosomal recessive woolly hair, which is caused by founder pathogenic variants in the lipase H (LIPH) gene, is the most prevalent hereditary ha...
Source: The Keio Journal of Medicine - July 5, 2023 Category: Universities & Medical Training Authors: Yutaka Shimomura Source Type: research
