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Comparison of acceptability & amp; efficacy of thermal ablation (thermocoagulation) & amp; cryotherapy in VIA positive cervical lesions: A pilot study
CONCLUSIONS: In the context of screen-and-treat programme in settings such as India, thermal ablation appears to be a better method of treatment than cryotherapy for cervical pre-cancerous lesions particularly in terms of better provision and client acceptability.PMID:38006345 | DOI:10.4103/ijmr.ijmr_1166_22 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Manju Lata Verma Parul Sharma Uma Singh Rekha Sachan Pushp Lata Sankhwar Source Type: research

Modulation of semaphorin 3C & amp; 4D expression in cancerous tissues from individuals with laryngeal squamous cell carcinoma
CONCLUSIONS: Increased expression of Sema3C but decreased expression of Sema4D in tumour tissue of LSCC may introduce these two growth factors as crucial mediators orchestrating tumour growth in individuals with LSCC. This result could open a new vision for the treatment of this malignancy.PMID:38006346 | DOI:10.4103/ijmr.ijmr_3148_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Marzieh Sajadian Bijan Khademi Leila Moinzadeh Abbas Ghaderi Abdollah Jafarzadeh Mahboobeh Razmkhah Source Type: research

Acinetobacter baumannii in suspected bacterial infections: Association between multidrug resistance, virulence genes, & amp; biofilm production
CONCLUSIONS: The majority of isolates studied were from lower respiratory tract specimens. The high MDR rate and its positive association with biofilm formation indicate the nosocomial distribution of A. baumannii. The biofilm formation and the presence of Bap were not interrelated, indicating that biofilm formation was not regulated by a single factor. The MDR rate and the presence of OmpA and Bap showed a positive association (P<0.05). The isolates co-harbouring different carbapenem resistance genes were the predominant biofilm producers, which will seriously limit the therapeutic options suggesting the need for stric...
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Deepan Gautam Karma Gurmey Dolma Bidita Khandelwal Ramesh Kumar Goyal Watcharapong Mitsuwan Maria de Lourdes Gomes Pereira Wiyada Kwanhian Klangbud Madhu Gupta Polrat Wilairatana Abolghasem Siyadatpanah Christophe Wiart Veeranoot Nissapatorn Source Type: research

Ocular morbidity among children (aged 6-18 yr) of the tribal area of Melghat, India: A community-based study
CONCLUSIONS: The prevalence of refractive error and VAD in this study was significantly higher than the rest of India and the world. For the prevention of childhood blindness, immediate intervention programme, including eye screening by trained paramedics, treatment by an ophthalmologist and prophylaxis, is crucial.PMID:38006342 | DOI:10.4103/ijmr.ijmr_3228_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Kavita A Satav Ashish R Satav Vibhawari S Dani Parikshit M Gogate Shraddha D Kumbhare Pradeep Reddy Source Type: research

Challenges in screening for sickle cell disease among newborns from the tribal region of Palghar, Maharashtra during the COVID-19 pandemic
CONCLUSIONS: The study emphasizes the importance of network building, use of virtual platform and engaging health workers in tribal settings. Such pragmatic approaches have the potential to pave a path for further implementation research involving specific interventions to improve health outcomes in tribal settings.PMID:38006343 | DOI:10.4103/ijmr.ijmr_3220_21 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Suchitra Surve Sanjay Chauhan Ragini Kulkarni Neha Salvi Anita Nadkarni Manisha Madkaikar Khushbu Chaudhary Abhijit Chavan Dayanand Suryavanshi Anil Thorat Harpreet Kaur Source Type: research

Correlation of microvessel density with histopathological parameters of carcinoma breast
CONCLUSIONS: A positive linear correlation of the microvessel counts and the NPI scores suggest that with an increase in tumour angiogenesis, there was increased proliferative potential. Based on the significant correlation between the microvessel counts and the vascular invasion of the tumour masses in this study, it can be assumed that there will be vascular invasion if the microvessel count is higher and vice-versa. Although it is established that angiogenesis and neovascularization are required for the expansion of the solid tumour tissue, the heterogeneous nature of this entity makes it difficult for obtaining a linea...
Source: The Indian Journal of Medical Research - November 25, 2023 Category: Biomedical Science Authors: Aditi V Goyal Samarth Shukla Sourya Acharya Sunita Vagha Suhas Jajoo Source Type: research

Serum anti-M üllerian hormone: A potential biomarker for polycystic ovary syndrome
CONCLUSIONS: The results of this study suggest that AMH can be considered as the most promising biomarker in PCOS women, particularly with phenotype A and phenotype D.PMID:37991331 | DOI:10.4103/ijmr.IJMR_4608_20 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 22, 2023 Category: Biomedical Science Authors: Ashutosh Halder Hemant Kumar Mona Sharma Manish Jain Amanpreet Kaur Kalsi Shivam Pandey Source Type: research

Early prediction of pre-eclampsia using circulating placental exosomes: Newer insights
Indian J Med Res. 2023 Oct 9. doi: 10.4103/ijmr.ijmr_2143_22. Online ahead of print.ABSTRACTPre-eclampsia (PE), a multifactorial de novo hypertensive pregnancy disorder, is one of the leading causes of foeto-maternal morbidity and mortality. Currently, antihypertensive drugs are the first-line therapy for PE and evidence suggests that low-dose aspirin initiated early in high risk pregnancies may reduce the risk of development or severity of PE. However, an early prediction of this disorder remains an unmet clinical challenge. Several potential serum biomarkers associated with maternal immunoregulation and placental angioge...
Source: The Indian Journal of Medical Research - November 21, 2023 Category: Biomedical Science Authors: Aishwarya Rao Uma Shinde Dhanjit Kumar Das Nafisa Balasinor Taruna Madan Source Type: research

Prevalence of postpartum depression & amp; anxiety among women in rural India: Risk factors & amp; psychosocial correlates
CONCLUSIONS: Rural Indian women experience PPD/A/both which causes stress and impacts their functionality, bonding with the infant and relationship with their spouse and parents. Higher education, marital satisfaction and higher support from partners and in-laws reduce the risk of developing PPD/A/both.PMID:37988000 | DOI:10.4103/ijmr.IJMR_3489_20 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 21, 2023 Category: Biomedical Science Authors: Vatsla Dadhwal Rajesh Sagar Debabani Bhattacharya Shashi Kant Puneet Misra Vandana Choudhary Perumal Vanamail Source Type: research

Factors associated with unexplained sudden deaths among adults aged 18-45 years in India - A multicentric matched case-control study
CONCLUSIONS: COVID-19 vaccination did not increase the risk of unexplained sudden death among young adults in India. Past COVID-19 hospitalization, family history of sudden death and certain lifestyle behaviors increased the likelihood of unexplained sudden death.PMID:37988028 | DOI:10.4103/ijmr.ijmr_2105_23 (Source: The Indian Journal of Medical Research)
Source: The Indian Journal of Medical Research - November 21, 2023 Category: Biomedical Science Authors: Manickam Ponnaiah Tarun Bhatnagar Rizwan Suliankachi Abdulkader Rajalakshmi Elumalai Janani Surya Kathiresan Jeyashree Muthusamy Santhosh Kumar Ranjithkumar Govindaraju Jeromie Wesley Vivian Thangaraj Hari Krishan Aggarwal Suresh Balan Tridip Dutta Baruah Source Type: research