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Proton Therapy in Breast Cancer: A Review of Potential Approaches for Patient Selection
Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241234788. doi: 10.1177/15330338241234788.ABSTRACTProton radiotherapy may be a compelling technical option for the treatment of breast cancer due to its unique physical property known as the "Bragg peak." This feature offers distinct advantages, promising superior dose conformity within the tumor area and reduced radiation exposure to surrounding healthy tissues, enhancing the potential for better treatment outcomes. However, proton therapy is accompanied by inherent challenges, primarily higher costs and limited accessibility when compared to well-developed photon irradiat...
Source: Technology in Cancer Research and Treatment - February 23, 2024 Category: Cancer & Oncology Authors: Xiao-Yu Wu Mei Chen Lu Cao Min Li Jia-Yi Chen Source Type: research

Targeting Receptor Tyrosine Kinases as a Novel Strategy for the Treatment of Triple-Negative Breast Cancer
Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241234780. doi: 10.1177/15330338241234780.ABSTRACTTriple-negative breast cancer (TNBC) comprises a group of aggressive and heterogeneous breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors. Nevertheless, the success of chemotherapeutic treatments is limited by their toxicity and development of acquired resistance leading to therapeutic failure and tumor relapse. Hence, there is an urgent need to explore novel targeted therapies for TNBC. Receptor tyrosine kinases (RTKs) are a family of transmembrane receptors that are key regulators of...
Source: Technology in Cancer Research and Treatment - February 23, 2024 Category: Cancer & Oncology Authors: Sara K Jaradat Nehad M Ayoub Ahmed H Al Sharie Julia M Aldaod Source Type: research

Computer Vision and Machine-Learning Techniques for Automatic 3D Virtual Images Overlapping During Augmented Reality Guided Robotic Partial Nephrectomy
CONCLUSION: The first technology allowed a successful anchoring of the 3D model to the kidney, despite minimal manual refinements. The second technology improved kidney automatic detection without relying on indocyanine injection, resulting in better organ boundaries identification during tests. Further studies are needed to confirm this preliminary evidence.PMID:38374643 | PMC:PMC10878218 | DOI:10.1177/15330338241229368 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 20, 2024 Category: Cancer & Oncology Authors: Daniele Amparore Michele Sica Paolo Verri Federico Piramide Enrico Checcucci Sabrina De Cillis Alberto Piana Davide Campobasso Mariano Burgio Edoardo Cisero Giovanni Busacca Michele Di Dio Pietro Piazzolla Cristian Fiori Francesco Porpiglia Source Type: research

Comparison of Treatment Outcomes Between Thoracoscopic Surgery and Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer
Conclusions: SBRT demonstrated similar overall survival compared to radical surgery, and associated with significantly reduced risk of tumor metastasis. Our study thereby suggests SBRT as the best treatment option for patients with inoperable NSCLC.PMID:38378004 | PMC:PMC10880525 | DOI:10.1177/15330338231219369 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 20, 2024 Category: Cancer & Oncology Authors: Qin Tian Xinxin Zhao Cong Zhang Nannan Tian Hongchun Bian Source Type: research

Evaluation of a New Method for CyberKnife Treatment for Central Lung and Mediastinal Tumors by Tracheobronchial Tracking
CONCLUSION: Our newly-developed tracheobronchial tracking method would be useful in facilitating minimally invasive CyberKnife treatment in certain cases of central lung and mediastinal tumors.PMID:38378006 | PMC:PMC10880520 | DOI:10.1177/15330338241232557 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 20, 2024 Category: Cancer & Oncology Authors: Toshihiro Suzuki Masahide Saito Hiroshi Takahashi Hidekazu Suzuki Koji Makino Koji Ueda Koji Mochizuki Zennosuke Mochizuki Hikaru Nemoto Naoki Sano Hiroshi Onishi Source Type: research

Computer Vision and Machine-Learning Techniques for Automatic 3D Virtual Images Overlapping During Augmented Reality Guided Robotic Partial Nephrectomy
CONCLUSION: The first technology allowed a successful anchoring of the 3D model to the kidney, despite minimal manual refinements. The second technology improved kidney automatic detection without relying on indocyanine injection, resulting in better organ boundaries identification during tests. Further studies are needed to confirm this preliminary evidence.PMID:38374643 | DOI:10.1177/15330338241229368 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 20, 2024 Category: Cancer & Oncology Authors: Daniele Amparore Michele Sica Paolo Verri Federico Piramide Enrico Checcucci Sabrina De Cillis Alberto Piana Davide Campobasso Mariano Burgio Edoardo Cisero Giovanni Busacca Michele Di Dio Pietro Piazzolla Cristian Fiori Francesco Porpiglia Source Type: research

A Novel Necroptosis-Related Signature Can Predict Prognosis and Chemotherapy Sensitivity in Multiple Myeloma
CONCLUSION: A systematic analysis of NRGs can help identify potential necroptosis-related mechanisms and provide novel biomarkers for MM prognosis prediction, tumor microenvironment evaluation, and personalized treatment planning.PMID:38361483 | PMC:PMC10874153 | DOI:10.1177/15330338241232554 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 16, 2024 Category: Cancer & Oncology Authors: Jun-Yao Jiang Fang-Yi Yao Jing Liu Xin-Lu Wang Bo Huang Fang-Min Zhong Xiao-Zhong Wang Source Type: research

A Novel Necroptosis-Related Signature Can Predict Prognosis and Chemotherapy Sensitivity in Multiple Myeloma
CONCLUSION: A systematic analysis of NRGs can help identify potential necroptosis-related mechanisms and provide novel biomarkers for MM prognosis prediction, tumor microenvironment evaluation, and personalized treatment planning.PMID:38361483 | DOI:10.1177/15330338241232554 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 16, 2024 Category: Cancer & Oncology Authors: Jun-Yao Jiang Fang-Yi Yao Jing Liu Xin-Lu Wang Bo Huang Fang-Min Zhong Xiao-Zhong Wang Source Type: research

Erratum to "Integrating Therapeutic Ultrasound With Nanosized Drug Delivery Systems in the Battle Against Cancer"
Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338231223384. doi: 10.1177/15330338231223384.NO ABSTRACTPMID:38343160 | PMC:PMC10860455 | DOI:10.1177/15330338231223384 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - February 12, 2024 Category: Cancer & Oncology Source Type: research