Technology in Cancer Research and Treatment This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Role of microRNAs in Regulating Cancer Cell Response to Oxaliplatin-Containing Regimens
Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231206003. doi: 10.1177/15330338231206003.ABSTRACTOxaliplatin (cyclohexane-1,2-diamine; oxalate; platinum [2+]) is a third-generation chemotherapeutic drug with anticancer effects. Oxaliplatin has a role in the treatment of several cancers. It is one of the few drugs which can eliminate the neoplastic cells of colorectal cancer. Also, it has an influential role in breast cancer, lung cancer, bladder cancer, prostate cancer, and gastric cancer. Although oxaliplatin has many beneficial effects in cancer treatment, resistance to this drug is in the way to cure neoplastic cells...
Source: Technology in Cancer Research and Treatment - October 18, 2023 Category: Cancer & Oncology Authors: Ali Tavakoli Pirzaman Manijeh Ebrahimzadeh Pirshahid Bahareh Babajani Amirhossein Rahmati Shokat Niknezhad Rezvan Hosseinzadeh Mehdi Taheri Faezeh Ebrahimi-Zadeh Shahrbanoo Doostmohamadian Sohrab Kazemi Source Type: research

Neutrophil-to-Lymphocyte Ratio and Early Tumor Shrinkage as Predictive Biomarkers in Unresectable Hepatocellular Carcinoma Patients Treated With Lenvatinib, PD-1 Inhibitors, in Combination With TACE
Conclusion: NLR has the potential to identify which patients would benefit from this triple therapy, and when combined with ETS, it has the potential to provide greater predictive power in selecting the appropriate candidates for this combination treatment.PMID:37849287 | DOI:10.1177/15330338231206704 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 18, 2023 Category: Cancer & Oncology Authors: Shuping Qu Dong Wu Zhiming Hu Source Type: research

Exploration of Chick Embryo and Chorioallantoic Membrane on Imaging Navigated Platforms for Anticancer Pharmaceutical Evaluations
Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231206985. doi: 10.1177/15330338231206985.ABSTRACTConforming to the current replace-reduce-refine 3Rs' guidelines in animal experiments, a series of explorative efforts have been made to set up operable biomedical imaging-guided platforms for qualitative and quantitative evaluations on pharmacological effects of tumor vascular-disrupting agents (VDAs), based on the chick embryos (CEs) with its chorioallantoic membrane (CAM), in this overview. The techniques and platforms have been hierarchically elaborated, from macroscopic to microscopic and from overall to specific aspect...
Source: Technology in Cancer Research and Treatment - October 16, 2023 Category: Cancer & Oncology Authors: Lei Chen Mingyuan Yuan Xinqi Zhang Yongsheng Li Yuanbo Feng Jie Yu Walter Coudyzer Yiyang Xie Jiayue Xu Yuzhen Li Yue Li Yicheng Ni Source Type: research

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma
CONCLUSION: The nature of the humoral response against anti-GnRH, induced by vaccination may play a key role in activating additional immunological mechanisms. Collectively, these mechanisms could contribute significantly to the regulation of tumor growth.PMID:37828833 | PMC:PMC10576932 | DOI:10.1177/15330338231207318 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 13, 2023 Category: Cancer & Oncology Authors: Ana Cristina Campal-Espinosa Jes ús Arturo Junco-Barranco Franklin Fuentes-Aguilar Lesvia Calzada-Aguilera Annia Rivacoba-Betancourt Ranfis Humberto Rodr íguez-Bueno Ana Claudia Bover-Campal Eddy Emilio Bover-Fuentes Lourdes Gonz ález Lourdes de Quesad Source Type: research

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma
CONCLUSION: The nature of the humoral response against anti-GnRH, induced by vaccination may play a key role in activating additional immunological mechanisms. Collectively, these mechanisms could contribute significantly to the regulation of tumor growth.PMID:37828833 | DOI:10.1177/15330338231207318 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 13, 2023 Category: Cancer & Oncology Authors: Ana Cristina Campal-Espinosa Jes ús Arturo Junco-Barranco Franklin Fuentes-Aguilar Lesvia Calzada-Aguilera Annia Rivacoba-Betancourt Ranfis Humberto Rodr íguez-Bueno Ana Claudia Bover-Campal Eddy Emilio Bover-Fuentes Lourdes Gonz ález Lourdes de Quesad Source Type: research

The Emerging Role of Exosomal miRNAs as Biomarkers for Early Cancer Detection: A Comprehensive Literature Review
Technol Cancer Res Treat. 2023 Jan-Dec;22:15330338231205999. doi: 10.1177/15330338231205999.ABSTRACTA significant number of cancer-related deaths are recorded globally each year, despite attempts to cure this illness. Medical science is working to develop new medication therapies as well as to find ways to identify this illness as early as possible, even using noninvasive techniques. Early detection of cancer can greatly aid its treatment. Studies into cancer diagnosis and therapy have recently shifted their focus to exosome (EXO) biomarkers, which comprise numerous RNA and proteins. EXOs are minuscule goblet vesicles that...
Source: Technology in Cancer Research and Treatment - October 11, 2023 Category: Cancer & Oncology Authors: Ali Jafari Keyvan Karimabadi Aso Rahimi Gelavizh Rostaminasab Mozafar Khazaei Leila Rezakhani Touraj Ahmadi Jouybari Source Type: research

Modified Tubeless Ureterocutaneostomy in High-Risk Patients After Radical Cystectomy and its Long-Term Clinical Outcomes
CONCLUSION: Our modified cutaneous ureterostomy method may provide an effective and simple approach to tubeless cutaneous ureterostomy in elderly and high-risk patients.PMID:37807703 | PMC:PMC10563461 | DOI:10.1177/15330338231192906 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 9, 2023 Category: Cancer & Oncology Authors: Mingyong Li Xiaowen Fu Xiongbing Zu Jinbo Chen Minfeng Chen Source Type: research

Predictive Value of the Neutrophil-Lymphocyte Ratio for Tumor Regression Grade and Prognosis of Local Advanced Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy
CONCLUSION: This study demonstrated that a lower pre-NLR was probably associated with a greater rate of TRG in LARC patients undergoing nCRT. Furthermore, the pre-NLR was credibly correlated with OS in LARC patients undergoing nCRT. Meanwhile, we constructed a nomogram for predicting the prognosis in LARC patients undergoing nCRT.PMID:37807729 | PMC:PMC10563499 | DOI:10.1177/15330338231202611 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 9, 2023 Category: Cancer & Oncology Authors: Shuofeng Li Dingyuan Wang Ran Wei Guanhua Yu Xishan Wang Zheng Jiang Source Type: research

Modified Tubeless Ureterocutaneostomy in High-Risk Patients After Radical Cystectomy and its Long-Term Clinical Outcomes
CONCLUSION: Our modified cutaneous ureterostomy method may provide an effective and simple approach to tubeless cutaneous ureterostomy in elderly and high-risk patients.PMID:37807703 | DOI:10.1177/15330338231192906 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 9, 2023 Category: Cancer & Oncology Authors: Mingyong Li Xiaowen Fu Xiongbing Zu Jinbo Chen Minfeng Chen Source Type: research

Predictive Value of the Neutrophil-Lymphocyte Ratio for Tumor Regression Grade and Prognosis of Local Advanced Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy
CONCLUSION: This study demonstrated that a lower pre-NLR was probably associated with a greater rate of TRG in LARC patients undergoing nCRT. Furthermore, the pre-NLR was credibly correlated with OS in LARC patients undergoing nCRT. Meanwhile, we constructed a nomogram for predicting the prognosis in LARC patients undergoing nCRT.PMID:37807729 | DOI:10.1177/15330338231202611 (Source: Technology in Cancer Research and Treatment)
Source: Technology in Cancer Research and Treatment - October 9, 2023 Category: Cancer & Oncology Authors: Shuofeng Li Dingyuan Wang Ran Wei Guanhua Yu Xishan Wang Zheng Jiang Source Type: research