Ablation of Small Renal Masses
Renal cell carcinoma is most commonly diagnosed in the sixth or seventh decade of life. Historically, surgical extirpation was the gold standard treatment option for small renal masses. However, given the comorbidities in this elderly population, not all patients are candidates for surgery. The development of minimally invasive ablative therapies has solved the surgical dilemma in this patient population. Furthermore, the 2017 American Urological Association guidelines recommends consideration of percutaneous image guided thermal ablation as a treatment option for masses smaller than 3 cm even in healthy individuals. (Sour...
Source: Techniques in Vascular and Interventional Radiology - June 4, 2020 Category: Radiology Authors: Mohamed E. Abdelsalam, Kamran Ahrar Source Type: research

Irreversible Electroporation for Locally Advanced Pancreatic Cancer
Several minimally invasive image guided tumor ablation techniques have been added to the treatment spectrum for locally advanced pancreatic cancer (LAPC). Irreversible electroporation (IRE) might have a significant additive value in the management of this difficult-to-treat disease.As opposed to thermal ablative techniques, IRE induces cell death by the delivery of high-voltage electrical pulses. The electrical energy disrupts the cellular membrane integrity, causes loss of cellular homeostasis and ultimately results in cell death. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - June 4, 2020 Category: Radiology Authors: Florentine E.F. Timmer, Bart Geboers, Alette H. Ruarus, Evelien A.C. Schouten, Sanne Nieuwenhuizen, Robbert S. Puijk, Jan J.J. de Vries, Martijn R. Meijerink, Hester J. Scheffer Source Type: research

“How We Do It” – A Practical Approach to Percutaneous Adrenal Ablation Techniques
This article serves as a brief but comprehensive review of preprocedural work-up and planning before an adrenal mass ablation, as well as a discussion on ablation techniques, associated challenges and solutions, and management of expected and unexpected outcomes. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - June 4, 2020 Category: Radiology Authors: Barbara Manchec, Yilun Koethe, Brian Schiro, Constantino Pe ña, Ripal Gandhi Source Type: research

Editorial Board
(Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - May 31, 2020 Category: Radiology Source Type: research

Bariatric Embolization: A Narrative Review of Clinical Data From Human Trials
Bariatric arterial embolization (BAE) is a novel technique that is investigated as an alternative, often supplementary, method for weight management. BAE reduces blood perfusion to the gastric fundus, and thus, reduces the production of appetite-inducing hormones. No randomized controlled trial has evaluated the efficacy of BAE to date. Available evidence from published studies include retrospective evaluations of patients undergoing left gastric artery embolization for gastrointestinal bleeding, and early prospective, single-arm clinical trials. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 27, 2020 Category: Radiology Authors: Nima Hafezi-Nejad, Christopher R. Bailey, Clifford R. Weiss Source Type: research

An Introduction to Current State of Obesity Interventions: A Guide for the Interventional Radiologist
No other specialty sits so firmly at the intersection of Translational Research and Clinical Application than does Interventional Radiology. This privileged location, coupled with a drive to innovate, re-invent ourselves, and bring cutting edge care to new patient populations, has led to the rapid expansion of Interventional Radiology into nearly every area of Medicine. In doing so we have created minimally invasive solutions to some of the most challenging clinical problems. What other disease process is currently more prevalent and destructive than Obesity, an epidemic that affects both adults and children throughout the...
Source: Techniques in Vascular and Interventional Radiology - January 26, 2020 Category: Radiology Authors: Clifford R. Weiss Source Type: research

Aspiration Therapy
Aspiration therapy is a novel, endoscopic bariatric therapy that allows patients to remove a portion of an ingested meal through a modified percutaneous gastrostomy tube, called an A-Tube. Weight loss results from both fewer calories consumed, and from modifications in lifestyle and mealtime behaviors that patients make as a result of having the device installed. The first commercially available device for aspiration therapy, the AspireAssist (Aspire Bariatrics, King of Prussia, PA), was approved by the Food and Drug Administration in 2016 for weight loss for greater than 6 months duration in patients with a body mass inde...
Source: Techniques in Vascular and Interventional Radiology - January 26, 2020 Category: Radiology Authors: Eric C. Swei, Shelby A. Sullivan Source Type: research

Rationale and Preclinical Data Supporting Bariatric Arterial Embolization
The prevalence of obesity is increasing globally, leading to significantly increased morbidity, mortality, and health care costs. However, there is a lack of effective treatment options that can treat patients with obesity less invasively than with bariatric surgery. Bariatric arterial embolization (BAE) is an image-guided, minimally invasive, percutaneous procedure that is currently being investigated in preclinical animal models and early clinical trials. If successful, BAE may represent a viable interventional approach for obesity treatment. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 23, 2020 Category: Radiology Authors: Yingli Fu, Dara L. Kraitchman Source Type: research

Current and Future Endoscopic Weight Loss Solutions
Obesity poses a significant health care concern in the United States, with 39.8% of adults being classified as obese. Several different methods have been introduced to combat obesity, from medical therapy to surgical options. Bariatric surgery has been demonstrated to be superior to medical therapy alone for weight loss in obese patients. Despite this information, only about 1% of eligible patients undergo bariatric surgery per year. The reason for this treatment gap is multifactorial, but patient apprehension to undergo surgery is a major driving force. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 22, 2020 Category: Radiology Authors: Leena Khaitan, Brian Shea Source Type: research

Percutaneous CT-Guided Cryovagotomy
There are a number of pathologic conditions in the human body that may be modified by the interruption of neural signaling, both related to pain and otherwise. Many of these treatments currently involve implantable neuromodulation or frank surgical neural ligation, representing opportunities for the implementation of percutaneous device-mediated cryoneurolysis in interventional radiology. Computed tomography-guided cryovagotomy for the management of mild to moderate obesity represents one such opportunity currently under investigation. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 21, 2020 Category: Radiology Authors: J.D. Prologo Source Type: research

Food and Drug Administration's Perspective on Medical Devices Intended for Weight Loss: A Guide for the Interventional Radiologist
Medical devices can help patients lose weight. The Food and Drug Administration (FDA) Center for Devices and Radiological Health is responsible for assuring the safety and effectiveness of devices used for weight loss. Interventional radiologists may conduct clinical studies of devices for weight loss, such as embolization beads to stop blood flow to gastric arteries or cryoablation systems to ablate metabolism-linked nerves. The purposes of this paper are (1) to clarify the FDA's role providing regulatory oversight of clinical studies of medical devices; (2) to explain how to engage with the FDA; and (3) to provide inform...
Source: Techniques in Vascular and Interventional Radiology - January 19, 2020 Category: Radiology Authors: A.K. Marrone Source Type: research

Current State of Bariatric Surgery: Procedures, Data, and Patient Management
Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 17, 2020 Category: Radiology Authors: Ann M. Rogers Source Type: research

Obesity: Scope, Lifestyle Interventions, and Medical Management
Obesity is a public health epidemic in the United States, with implications for patients across many organ systems. Despite improvements in understanding the pathophysiology and increasing number of therapies for obesity, its prevalence continues to rise. The purpose of this review is to provide the interventional radiologist with an understanding of (1) the epidemiology of obesity; (2) the impact of obesity on patients and the healthcare system; (3) the causes of obesity; (4) conservative management of obesity; and (5) pharmacologic management of obesity. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 17, 2020 Category: Radiology Authors: Benjamin J. McCafferty, James O. Hill, Andrew J. Gunn Source Type: research

Current State of Bariatric Surgery - Procedures, Data, and Patient Management
Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality. (Source: Techniques in Vascular and Interventional Radiology)
Source: Techniques in Vascular and Interventional Radiology - January 17, 2020 Category: Radiology Authors: Ann M. Rogers Source Type: research