Current State of Bariatric Surgery - Procedures, Data, and Patient Management

Bariatric surgery comprises a group of operative procedures designed to improve weight-related medical conditions. In the United States, these include vertical sleeve gastrectomy, Roux-en-Y gastric bypass, adjustable gastric banding, and the duodenal switch procedure. Bariatric surgery is the only durable and effective way for most humans to lose a significant amount of weight, and see improvement in obesity-related comorbidities. It can improve quality of life, prevent a number of cancers, and decrease overall mortality.
Source: Techniques in Vascular and Interventional Radiology - Category: Radiology Authors: Source Type: research

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Publication date: Available online 2 August 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Jérémie Thereaux, Thomas Lesuffleur, Sébastien Czernichow, Arnaud Basdevant, Simon Msika, David Nocca, Bertrand Millat, Anne Fagot-CampagnaSummaryBackgroundConcerns are rising about the late adverse events following gastric bypass and sleeve gastrectomy. We aimed to assess, over a 7-year period, the late adverse events after gastric bypass and sleeve gastrectomy compared with matched control groups.MethodsIn this nationwide, observational, population-based, cohort study, we used data extracted from ...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Conclusions: Bariatric surgery appears to be capable of partially reversing the obesity-related epigenome. The identification of potential epigenetic biomarkers predictive for the success of bariatric surgery may open new doors to personalized therapy for severe obesity. Introduction Obesity is currently a huge healthcare problem, worldwide, and is a risk factor for several diseases such as type 2 diabetes (T2D), cardiovascular disease and cancer (1). As the prevalence of obesity reaches pandemic proportions, this metabolic disease is estimated to become the biggest cause of mortality in the near future (2). In fact,...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Bariatric surgery is the most effective therapy for patients with morbid obesity today [1]. However, the types of operation are still evolving. Sleeve gastrectomy (SG) recently has quickly gained popularity as a primary bariatric surgery worldwide [2,3]. SG plus duodeno-jejunostomy (SG-DJB) was introduced in 2007 as an alternative to Roux-en-Y gastric bypass (RYGB) because the issue of gastric cancer arising from the excluded stomach [4]. SG-DJB can be regarded as a modification of duodenal switch (DS) with short bypass limb and fewer nutritional problems [5].
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original article Source Type: research
Bariatric surgery is the most effective therapy for patients with morbid obesity today [1]. However, the types of operation are still in evolving. Sleeve gastrectomy (SG) recently has quickly gained popularity as a primary bariatric surgery worldwide [2, 3]. SG plus duodeno-jejunostomy (SG-DJB) was introduced in 2007 as an alternative to Roux-en-Y gastric bypass (RYGB) because the issue of gastric cancer arising from the excluded stomach [4]. SG-DJB can be regarded as a modification of duodenal switch (DS) with short bypass limb and fewer nutritional problems [5].
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
Background: Women of child-bearing potential generally experience an increase in fertility following bariatric surgery. However, the most commonly performed bariatric operations, Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (VSG), may impair absorption of oral contraceptives, potentially rendering them ineffective. Moreover, women desiring to lose weight should avoid contraceptive medications known to cause weight gain. As an alternative, bilateral salpingectomy provides highly reliable contraception and has even been proposed as a strategy to reduce the risk of ovarian, tubal, and peritoneal cancers.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
CONCLUSION: Bariatric surgery is associated with decreased risk of hormone-related cancers, whereas gastric bypass might increase the risk of colorectal cancer. PMID: 30003539 [PubMed - as supplied by publisher]
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
Roux-en-Y gastric bypass (RYGB) improves comorbidities such as diabetes and hypertension and lowers the risk of obesity-related cancers. To better understand the physiologic and genetic influences of bariatric surgery, a reliable murine model is needed that can be extended to genetically engineered mice. Given the complexity of these procedures, few researchers have successfully implemented these techniques beyond larger rodent models. The purpose of our study was to develop a technically feasible and reproducible murine model for RYGB and sleeve gastrectomy (SG).
Source: Journal of Surgical Research - Category: Surgery Authors: Source Type: research
ConclusionThe current preliminary study thus identified potentially carcinogenic proteins in obese patients. Surgical weight loss resulted in the not detection of these proteins.
Source: Obesity Surgery - Category: Surgery Source Type: research
We present the case of a 55-year-old super-super obese man with a family history of GC and antral gastritis with extensive intestinal metaplasia at preoperative upper endoscopy, who underwent laparoscopic RYGBP with remnant gastrectomy. PMID: 29350665 [PubMed - in process]
Source: Acta Bio-Medica : Atenei Parmensis - Category: General Medicine Authors: Tags: Acta Biomed Source Type: research
ConclusionsAlthough both LSG and LSG/DJB have good antidiabetic effects in Japanese obese patients, LSG/DJB is more effective for patients with lower ABCD scores.
Source: Obesity Surgery - Category: Surgery Source Type: research
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