Irreversible Electroporation for Locally Advanced Pancreatic Cancer

Several minimally invasive image guided tumor ablation techniques have been added to the treatment spectrum for locally advanced pancreatic cancer (LAPC). Irreversible electroporation (IRE) might have a significant additive value in the management of this difficult-to-treat disease.As opposed to thermal ablative techniques, IRE induces cell death by the delivery of high-voltage electrical pulses. The electrical energy disrupts the cellular membrane integrity, causes loss of cellular homeostasis and ultimately results in cell death.

Source: Techniques in Vascular and Interventional Radiology - June 4, 2020 Category: Radiology Authors: Florentine E.F. Timmer, Bart Geboers, Alette H. Ruarus, Evelien A.C. Schouten, Sanne Nieuwenhuizen, Robbert S. Puijk, Jan J.J. de Vries, Martijn R. Meijerink, Hester J. Scheffer Source Type: research