Voluntary wheel running promotes resilience to the behavioral effects of unpredictable chronic mild stress in male and female mice
Stress. 2023 Apr 26:1-17. doi: 10.1080/10253890.2023.2203769. Online ahead of print.NO ABSTRACTPMID:37125617 | DOI:10.1080/10253890.2023.2203769 (Source: Stress)
Source: Stress - May 1, 2023 Category: Research Authors: Elias Elias Ariel Y Zhang Abigail G White Matthew J Pyle Melissa T Manners Source Type: research
From Ligands to Behavioral Outcomes: Understanding the Role of Mineralocorticoid Receptors in Brain Function
Stress. 2023 Apr 17:1-53. doi: 10.1080/10253890.2023.2204366. Online ahead of print.ABSTRACTStress is a normal response to situational pressures or demands. Exposure to stress activates the hypothalamic-pituitary-adrenal (HPA) axis and leads to the release of corticosteroids, which act in the brain via two distinct receptors: mineralocorticoid receptors (MR) and glucocorticoid receptors (GR). Persistent HPA axis overactivation or dysregulation can disrupt an individual's homeostasis, thereby contributing to an increased risk for mental illness. On the other hand, successful coping with stressful events involves adaptive an...
Source: Stress - April 17, 2023 Category: Research Authors: Huanqing Yang Sowmya Narayan Mathias V Schmidt Source Type: research
