Genome-wide association studies of stress score in a Korean Cohort
Stress. 2021 Oct 26:1-7. doi: 10.1080/10253890.2021.1992380. Online ahead of print.ABSTRACTDespite ongoing research on factors affecting stress, there is a shortage of research on genetic variation using single nucleotide polymorphisms (SNPs). Thus, this study aims to identify genes that may affect the risk of stress in a large-scale Korean cohort. The stress survey used in this study consisted of 40 questions, organized into the following four categories: 10 questions on General Stress (GenST); 10 questions on Mental Stress (MenST); 10 questions on Physical Stress (PhyST); and 10 questions on Activity Stress (ActST). An o...
Source: Stress - October 26, 2021 Category: Research Authors: Jiwon Yang Source Type: research

The association between chronic stress, hair cortisol, and angiographically documented coronary atherosclerosis, a case-control study
Stress. 2021 Oct 11:1-8. doi: 10.1080/10253890.2021.1985994. Online ahead of print.ABSTRACTCardiovascular diseases remain the principal contributor to global mortality and morbidity. Chronic stress has emerged as a strong prognostic factor for cardiovascular diseases. We aimed to measure hair cortisol concentration (HCC) in patients with angiographically confirmed coronary atherosclerosis and find the association between HCC and classic cardiovascular risk factors in a case-control study. The study included 500 angiographically confirmed coronary atherosclerosis patients and 500 age and sex-matched controls having no coron...
Source: Stress - October 11, 2021 Category: Research Authors: Asma Nafisa Feroza Hamid Wattoo Mazhar Qayyum Muhammad Gulfraz Source Type: research

Prenatal stress promotes insulin resistance without inflammation or obesity in C57BL/6J male mice
Stress. 2021 Sep 28:1-11. doi: 10.1080/10253890.2021.1978425. Online ahead of print.ABSTRACTDuring gestation, stress exposure increases the risk of developing cognitive and physiological alterations in either the long or short term. Among them, metabolic alterations have been described. Adipose tissue is responsible for the secretion of several factors involved in controlling body weight and energy expenditure, the regulation of insulin sensitivity, and the development of inflammation, among others. Moreover, the liver regulates glucose homeostasis and lipid metabolism, playing an essential role in developing insulin resis...
Source: Stress - September 28, 2021 Category: Research Authors: Sofia Quiroga Yamila Raquel Ju árez Mar ía Paula Marcone Mar ía Agustina Vidal Ana Mar ía Genaro Adriana Laura Burgue ño Source Type: research

Exploring the metabolomic profile of cerebellum after exposure to acute stress
Stress. 2021 Sep 23:1-13. doi: 10.1080/10253890.2021.1973997. Online ahead of print.ABSTRACTPsychological stress and stress-related disorders constitute a major health problem in modern societies. Although the brain circuits involved in emotional processing are intensively studied, little is known about the implication of cerebellum in stress responses whereas the molecular changes induced by stress exposure in cerebellum remain largely unexplored. Here, we investigated the effects of acute stress exposure on mouse cerebellum. We used a forced swim test (FST) paradigm as an acute stressor. We then analyzed the cerebellar m...
Source: Stress - September 23, 2021 Category: Research Authors: Aikaterini Iliou Angeliki-Maria Vlaikou Markus Nussbaumer Dimitra Benaki Emmanuel Mikros Evangelos Gikas Michaela D Filiou Source Type: research

Differences between adult and adolescent male mice in approach/avoidance and expression of hippocampal NPY in response to acute footshock
Stress. 2021 Sep 21:1-13. doi: 10.1080/10253890.2021.1976139. Online ahead of print.ABSTRACTAnxiety disorders are the most common neuropsychiatric disorders diagnosed in adolescence and adulthood. Stress can lead to an increase in anxiety-related behaviors, although the consequences of stress in rodents are typically investigated only in adults. The levels of Neuropeptide Y (NPY), a mediator of stress resilience, are reduced in adult patients with Post-Traumatic Stress Disorder. For rodents, footshock is a physical stressor that increases anxiety-like behavior and reduces NPY in adults, however, the effects in adolescents ...
Source: Stress - September 21, 2021 Category: Research Authors: Mariana A Cortes Katelynn M Corder Lynn E Dobrunz Source Type: research

Males with low risk-taking propensity overestimate risk under acute psychological stress
Stress. 2021 Sep 20:1-13. doi: 10.1080/10253890.2021.1957824. Online ahead of print.ABSTRACTArousing research has investigated stressed individuals' decision biases, but whether and how stress and individual traits interact to impact the underlying decision-making process is unknown. Here, we aim to explore the effect of acute stress on the interaction between the objective level of risk and subjective risk preference (i.e. risk-taking propensity). Eighty-three healthy males participated in the study. We adopted the Trier Social Stress Test (TSST) to induce acute psychological stress and categorized participants into the h...
Source: Stress - September 20, 2021 Category: Research Authors: Peishan Wang Ruolei Gu Jingyu Zhang Xianghong Sun Liang Zhang Source Type: research

Prenatally stress-exposed male rats present lower theta prefrontal activity during attention behaviors to receptive females
Stress. 2021 Sep 16:1-9. doi: 10.1080/10253890.2021.1976140. Online ahead of print.ABSTRACTPrenatal stress affects brain functionality and sexual behavior. The medial prefrontal cortex (mPFC) participates in the integration and processing of sexual stimuli. Electroencephalographic (EEG) theta activity has been associated with attention as well as rewarding and sexually motivated states. Considering that the induction of sexual motivation requires attention to, and the adequate processing of, sexual stimuli, this study aimed to evaluate the effects of exposure to stress during the prenatal period on EEG activity in the mPFC...
Source: Stress - September 16, 2021 Category: Research Authors: Marisela Hern ández-González Rodrigo Maldonado Enrique Hern ández-Arteaga Miguel Angel Guevara Source Type: research

Stress and steroid interaction modulates expression of estrogen receptor alpha in the brain, pituitary, and testes of immature < em > Gallus gallus domesticus < /em >
Stress. 2021 Aug 23:1-14. doi: 10.1080/10253890.2021.1965119. Online ahead of print.ABSTRACTIn nature, food availability stimulates hypothalamo-pituitary-gonadal (HPG) axis while its scarcity induces stress, which further stimulates hypothalamo-pituitary-adrenal (HPA) axis producing a detrimental effect on the avian reproductive physiology. The present experiment was designed to examine the interaction of stress like food restriction and estradiol on male reproductive physiology with special emphasis on estrogen receptor alpha (ERα) as these play crucial role in reproduction. To achieve this, 60 day old White Leghorn...
Source: Stress - August 23, 2021 Category: Research Authors: Kalpana Baghel Rashmi Srivastava Source Type: research

Effects of the odorant Hedione on the human stress response
Stress. 2021 Aug 17:1-6. doi: 10.1080/10253890.2021.1961128. Online ahead of print.ABSTRACTOlfactory cues can affect subjective and autonomic manifestations of the human stress response, but evidence of altered endocrine stress reactivity is inconclusive. In the present study, we investigated effects of the odorant Hedione on the human stress response. We exposed 56 women in their follicular phases to a stressor in a room scented with Hedione or no odor. Subjective stress was captured via repeated self-report measurements and the assessment of anticipatory appraisal. As physiological markers of stress, we assessed blood pr...
Source: Stress - August 17, 2021 Category: Research Authors: Anika P ützer Oliver T Wolf Source Type: research