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CCK1R2R < sup > -/- < /sup > ameliorates myocardial damage caused by unpredictable stress via altering fatty acid metabolism
Stress. 2023 Sep 4:1-17. doi: 10.1080/10253890.2023.2254566. Online ahead of print.ABSTRACTHeart is the main organ of the circulatory system and requires fatty acids to maintain its activity. Stress is a contributor to aggravate cardiovascular diseases and even death, and exacerbated the abnormal lipid metabolism. The cardiac metabolism may be disturbed by stress. Cholecystokinin (CCK), which is a classical peptide hormone, and its receptor (CCKR) are expressed in myocardial cell and affect cardiovascular function. Nevertheless, under stress, the exactly role of CCKR on cardiac function and cardiac metabolism is unknown an...
Source: Stress - September 4, 2023 Category: Research Authors: Zhi-Hua Zhang Chen-Teng Yang Xiao-Rui Su Ya-Ping Li Xiao-Jing Zhang Song-Jun Wang Bin Cong Source Type: research