RSC - Nat. Prod. Rep. latest articles This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Huperzine alkaloids: forty years of total syntheses
Nat. Prod. Rep., 2024,41,59-84 DOI: 10.1039/D3NP00029J, Review ArticleBichu Cheng, Lili Song, Fener Chen This review discusses the synthetic chemistry of huperzine A, a potent inhibitor of acetylcholine esterase (AChE), followed by the advancements in other alkaloids of the family. The analogs and medicinal chemistry of huperzines are summarized. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 24, 2024 Category: Chemistry Authors: Bichu Cheng Source Type: research

Natural ten-membered lactones: sources, structural diversity, biological activity, and intriguing future
Nat. Prod. Rep., 2024,41,85-112 DOI: 10.1039/D3NP00013C, Review ArticleVsevolod Dubovik, Anna Dalinova, Alexander Berestetskiy Ten-membered lactones (TMLs) are an interesting and diverse group of natural polyketides that are abundant in fungi and, to a lesser extent, in bacteria, marine organisms, and insects. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 24, 2024 Category: Chemistry Authors: Vsevolod Dubovik Source Type: research

Structural insights into the diverse prenylating capabilities of DMATS prenyltransferases
Nat. Prod. Rep., 2024,41,113-147 DOI: 10.1039/D3NP00036B, Review ArticleEvan T. Miller, Oleg  V. Tsodikov, Sylvie Garneau-Tsodikova This review unpacks the accumulated knowledge of the structural bases of the unique properties and capabilities of DMATS-type prenyltransferases (PTs) that make them promising biocatalysts. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 24, 2024 Category: Chemistry Authors: Evan T. Miller Source Type: research

Biosynthesis of fungal terpenoids
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00052D, Review ArticlePan Luo, Jia-Hua Huang, Jian-Ming Lv, Gao-Qian Wang, Dan Hu, Hao Gao This review covers all fungal terpenoid cyclases (TCs), including class I and II TCs as well as emerging UbiA-type TCs, together with their tailoring enzymes, focusing on newly identified TCs and tailoring enzymes from 2015 to August 2023. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 24, 2024 Category: Chemistry Authors: Pan Luo Source Type: research

Promoter engineering of natural product biosynthetic gene clusters in actinomycetes: concepts and applications
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00049D, Review ArticleChang-Hun Ji, Hyun-Woo Je, Hiyoung Kim, Hahk-Soo Kang Promoter engineering has been used to improve production titers of natural products or to activate transcriptionally silent BGCs. This review summarizes 10 years of progress in promoter engineering approaches in natural products research. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 23, 2024 Category: Chemistry Authors: Chang-Hun Ji Source Type: research

Correction: Future antimalarials from Artemisia? A rationale for natural product mining against drug-refractory Plasmodium stages
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Alexandre Maciuk, Dominique Mazier, Romain Duval To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 17, 2024 Category: Chemistry Authors: Alexandre Maciuk Source Type: research

Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Jonas Motter, Caecilie M. M. Benckendorff, Sarah Westarp, Peter Sunde-Brown, Peter Neubauer, Anke Kurreck, Gavin J. Miller This Highlight offers a perspective on recent strategies for synthesising purine nucleoside antibiotics, an untapped source of natural products for developing novel antimicrobial agents. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 10, 2024 Category: Chemistry Authors: Jonas Motter Source Type: research

Nitrile biosynthesis in nature: how and why?
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00028A, Review ArticleMingyu Liu, Shengying Li Natural nitriles comprise a small set of secondary metabolites which however show intriguing chemical and functional diversity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 9, 2024 Category: Chemistry Authors: Mingyu Liu Source Type: research

The shikimate pathway: gateway to metabolic diversity
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00037K, Review ArticleVikram V. Shende, Katherine D. Bauman, Bradley S. Moore The shikimate pathway is the metabolic process responsible for the biosynthesis of proteinogenic, aromatic amino acids as well as a bevy of specialized metabolites in bacteria, fungi, and plants. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 3, 2024 Category: Chemistry Authors: Vikram V. Shende Source Type: research

Correction: Hot off the Press
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Robert A. Hill, Andrew Sutherland To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - January 3, 2024 Category: Chemistry Authors: Robert A. Hill Source Type: research

The pearl jubilee of microcin J25: thirty years of research on an exceptional lasso peptide
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00046J, Review ArticleFernando Baquero, Konstantinos Beis, David J. Craik, Yanyan Li, A. James Link, Sylvie Rebuffat, Ra úl Salomón, Konstantin Severinov, Séverine Zirah, Julian D. Hegemann A lasso peptide takes the spotlight. This review summarizes 30 years of research on microcin J25 and covers everything from its discovery in 1992, through the study of its antimicrobial activity, to its most recent application in bioengineering. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal S...
Source: RSC - Nat. Prod. Rep. latest articles - January 2, 2024 Category: Chemistry Authors: Fernando Baquero Source Type: research

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Thilina U. Jayawardena, Natacha Merindol, Nuwan Sameera Liyanage, Isabel Desgagn é-Penix Amaryllidaceae alkaloids (AAs) are a unique class of specialized metabolites containing heterocyclic nitrogen bridging that play a distinct role in higher plants. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - December 22, 2023 Category: Chemistry Authors: Thilina U. Jayawardena Source Type: research

The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00035D, Review ArticleAntonio Evidente This review describes the chemistry, biosynthesis, and biological activity of ophiobolin A and sphaeropsidin A, two phytotoxic terpenes with potential anticancer activity, and that of their natural analogues and derivatives. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - December 22, 2023 Category: Chemistry Authors: Antonio Evidente Source Type: research

Class II terpene cyclases: structures, mechanisms, and engineering
Nat. Prod. Rep., 2024, Advance Article DOI: 10.1039/D3NP00033H, Review ArticleXingming Pan, Jeffrey D. Rudolf, Liao-Bin Dong This review offers an overview of the canonical and noncanonical class II terpene cyclases, including sesquiterpene, diterpene, triterpene, and meroterpenoid cyclases. It delves into their sequences, structures, mechanisms, and engineering studies. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - December 18, 2023 Category: Chemistry Authors: Xingming Pan Source Type: research

Chemistry and biology of specialized metabolites produced by Actinomadura
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Yousef Dashti, Jeff Errington Actinomadura represents a promising source of natural products. This review emphasizes the specialized metabolites produced by this genus, their biological activities, and selected biosynthetic pathways. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - December 15, 2023 Category: Chemistry Authors: Yousef Dashti Source Type: research