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Artificial intelligence in microbial natural product drug discovery: current and emerging role
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00035K, Review ArticleVinodh J. Sahayasheela, Manendra B. Lankadasari, Vipin Mohan Dan, Syed G. Dastager, Ganesh N. Pandian, Hiroshi Sugiyama Artificial Intelligence (AI) is being widely recognized these days for natural product research. In this article, we highlight the importance of AI and its application in various stages of natural product identification and characterization. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 26, 2022 Category: Chemistry Authors: Vinodh J. Sahayasheela Source Type: research

Brief overview of recently reported misassigned natural products and their in silico revisions enabled by DU8ML, a machine learning-augmented DFT computational NMR method
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00051B, HighlightIvan M. Novitskiy, Andrei G. Kutateladze A personal selection of recent misassigned structures of natural products and their revision with the aid of DU8ML, a machine learning-augmented DFT computational method for fast and accurate calculations of NMR chemical shifts and coupling constants. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 25, 2022 Category: Chemistry Authors: Ivan M. Novitskiy Source Type: research

Integrative omics approaches for biosynthetic pathway discovery in plants
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Kumar Saurabh Singh, Justin J. J. van der Hooft, Saskia C. M. van Wees, Marnix H. Medema This review discusses genomics-, transcriptomics- and metabolomics-based plant biosynthetic pathway discovery, and highlights the potential for integrative omics approaches. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 23, 2022 Category: Chemistry Authors: Kumar Saurabh Singh Source Type: research

Biogenetic and biomimetic synthesis of natural bisditerpenoids: hypothesis and practices
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00039C, Review ArticleYibo Chang, Chengpeng Sun, Chao Wang, Xiaokui Huo, Wenyu Zhao, Xiaochi Ma The review introduced the chemical diversity in structures and biosynthesis of interesting bisditerpenoids (diterpenoid dimers), and their biological functions. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 19, 2022 Category: Chemistry Authors: Yibo Chang Source Type: research

Recent ring distortion reactions for diversifying complex natural products
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00027J, Review ArticleYu Li, Shihao Cheng, Yun Tian, Yanan Zhang, Yu Zhao The ring distortion reactions recently used in complexity-to-diversity and pseudo natural product strategies for diversifying complex natural products have been overviewed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 16, 2022 Category: Chemistry Authors: Yu Li Source Type: research

Recent advances on marine mollusk-derived natural products: chemistry, chemical ecology and therapeutical potential
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00021K, Review ArticleZi-Hui Chen, Yue-Wei Guo, Xu-Wen Li This review summarizes the recent advances on the interesting secondary metabolites from marine mollusks, focusing on their structural features, possible chemo-ecological significance, and promising biological activities. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 9, 2022 Category: Chemistry Authors: Zi-Hui Chen Source Type: research

Hot off the Press
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP90026B, Hot off the Press ArticleRobert A. Hill, Andrew Sutherland A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as hyperispirone A fromHypericum beanii. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 5, 2022 Category: Chemistry Authors: Robert A. Hill Source Type: research

Egg toxic compounds in the animal kingdom. A comprehensive review
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00029F, Review ArticleMat ías L. Giglio, Wilhelm Boland, Horacio Heras This review gives an integrative approach to egg toxins and analyzes the trends and patterns in the animal kingdom, including their ecology, distribution, sources, occurrence, structure, function, relative toxicity, and mechanistic aspects. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 2, 2022 Category: Chemistry Authors: Mat ías L. Giglio Source Type: research

Biosynthesis, total synthesis, and pharmacological activities of aryltetralin-type lignan podophyllotoxin and its derivatives
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00028H, Review ArticleSiyu Shen, Yuru Tong, Yunfeng Luo, Luqi Huang, Wei Gao This paper mainly focused on the asymmetric synthesis of natural product PTOX by biosynthesis and total synthesis, and pharmacological activities of its derivatives. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - August 2, 2022 Category: Chemistry Authors: Siyu Shen Source Type: research

Signalling molecules inducing metamorphosis in marine organisms
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D1NP00073J, Review ArticleMaja Rischer, Huijuan Guo, Christine Beemelmanns Schematic representation of interkingdom-interactions mediated through bacterial signalling molecules present within a biofilm microenvironment. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - July 13, 2022 Category: Chemistry Authors: Maja Rischer Source Type: research

Microbial polyketides and their roles in insect virulence: from genomics to biological functions
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D1NP00058F, Review ArticleWachiraporn Toopaang, Warapon Bunnak, Chettida Srisuksam, Wilawan Wattananukit, Morakot Tanticharoen, Yu-Liang Yang, Alongkorn Amnuaykanjanasin Target sites of microbial polyketides are in the insect central nervous and immune systems. The compounds also modulate insect –microbial symbiosis. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - July 13, 2022 Category: Chemistry Authors: Wachiraporn Toopaang Source Type: research

Engineering the biosynthesis of fungal nonribosomal peptides
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00036A, Review ArticleLiwen Zhang, Chen Wang, Kang Chen, Weimao Zhong, Yuquan Xu, Istv án Molnár Fungal nonribosomal peptides (NRPs) and the related polyketide –nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of bioactive compounds, some of which have been developed into essential drugs. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - July 7, 2022 Category: Chemistry Authors: Liwen Zhang Source Type: research

Pitfalls in the structural elucidation of small molecules. A critical analysis of a decade of structural misassignments of marine natural products
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00023G, Review ArticleShou-Mao Shen, Giovanni Appendino, Yue-Wei Guo The article summarizes over 200 cases of misassigned MNPs, identifying major pitfalls still plaguing the structural elucidation of small molecules. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - June 30, 2022 Category: Chemistry Authors: Shou-Mao Shen Source Type: research

Functions and biosynthesis of plant signaling metabolites mediating plant –microbe interactions
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D2NP00010E, Review ArticleJingwei Yu, Xingzhao Tu, Ancheng C. Huang Plants shape their associated microbiota largely by synthesizing and exuding small molecules. This review highlights their roles, biosynthetic origins, and bioengineering potentials and strategies. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - June 30, 2022 Category: Chemistry Authors: Jingwei Yu Source Type: research

Recent advances in the synthesis of natural products containing the phloroglucinol motif
Nat. Prod. Rep., 2022, Advance Article DOI: 10.1039/D1NP00077B, Review ArticleYee Lin Phang, Song Liu, Changwu Zheng, Hongxi Xu Phloroglucinol-derived natural products possess notable bioactivities. This review summarizes the recent synthetic approaches to the natural products bearing a phloroglucinol motif, and demonstrates strategies to functionalize the phloroglucinols. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Nat. Prod. Rep. latest articles)
Source: RSC - Nat. Prod. Rep. latest articles - June 28, 2022 Category: Chemistry Authors: Yee Lin Phang Source Type: research