Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Comparison and multi-model inference of excess risks models for radiation-related solid cancer
Radiat Environ Biophys. 2023 Jan 21. doi: 10.1007/s00411-022-01013-0. Online ahead of print.ABSTRACTIn assessments of detrimental health risks from exposures to ionising radiation, many forms of risk to dose-response models are available in the literature. The usual practice is to base risk assessment on one specific model and ignore model uncertainty. The analysis illustrated here considers model uncertainty for the outcome all solid cancer incidence, when modelled as a function of colon organ dose, using the most recent publicly available data from the Life Span Study on atomic bomb survivors of Japan. Seven recent publi...
Source: Radiation and Environmental Biophysics - January 21, 2023 Category: Physics Authors: Alberto Stabilini Luana Hafner Linda Walsh Source Type: research

Concepts of association between cancer and ionising radiation: accounting for specific biological mechanisms
Radiat Environ Biophys. 2023 Jan 12. doi: 10.1007/s00411-022-01012-1. Online ahead of print.ABSTRACTThe probability that an observed cancer was caused by radiation exposure is usually estimated using cancer rates and risk models from radioepidemiological cohorts and is called assigned share (AS). This definition implicitly assumes that an ongoing carcinogenic process is unaffected by the studied radiation exposure. However, there is strong evidence that radiation can also accelerate an existing clonal development towards cancer. In this work, we define different association measures that an observed cancer was newly induce...
Source: Radiation and Environmental Biophysics - January 12, 2023 Category: Physics Authors: Markus Eidem ├╝ller Janine Becker Jan Christian Kaiser Alexander Ulanowski A Iulian Apostoaei F Owen Hoffman Source Type: research