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Modelling DTPA therapy following Am contamination in rats
Radiat Environ Biophys. 2023 Oct 13. doi: 10.1007/s00411-023-01046-z. Online ahead of print.ABSTRACTA major challenge in modelling the decorporation of actinides (An), such as americium (Am), with DTPA (diethylenetriaminepentaacetic acid) is the fact that standard biokinetic models become inadequate for assessing radionuclide intake and estimating the resulting dose, as DTPA perturbs the regular biokinetics of the radionuclide. At present, most attempts existing in the literature are empirical and developed mainly for the interpretation of one or a limited number of specific incorporation cases. Recently, several approache...
Source: Radiation and Environmental Biophysics - October 13, 2023 Category: Physics Authors: Manuel Kastl Olivier Gr émy Stephanie Lamart Augusto Giussani Wei Bo Li Christoph Hoeschen Source Type: research

Fractal analysis of the mandible cortical bone: correlation among fractal dimension values obtained by two processing methods from periapical radiograph and micro-computed tomography with cone-beam computed tomography
In conclusion, image processing with or without binarization revealed different values for FD, although showing agreement. The grayscale-based method retrieved FD values correlated with the gray levels and the cortical porous network, which means that FD can be a valuable index for mandibular cortical bone evaluation. FD is associated with mineralization and microarchitecture. Nevertheless, there was no correlation between FD values obtained from low- (DPR) and high-resolution (µCT) X-ray modalities with FD obtained from the in vivo CBCT.PMID:37792108 | DOI:10.1007/s00411-023-01045-0 (Source: Radiation and Environmental Biophysics)
Source: Radiation and Environmental Biophysics - October 4, 2023 Category: Physics Authors: Adriano de Oliveira Loures Matheus de Abreu Karina Lopes Devito Eric Flavio Grisolia-Seifert Katharina J ähn-Rickert Gustavo Davi Rabelo Source Type: research

Behavioral performance and microglial status in mice after moderate dose of proton irradiation
Radiat Environ Biophys. 2023 Oct 4. doi: 10.1007/s00411-023-01044-1. Online ahead of print.ABSTRACTCognitive impairment is a remote effect of gamma radiation treatment of malignancies. The major part of the studies on the effect of proton irradiation (a promising alternative in the treatment of radio-resistant tumors and tumors located close to critical organs) on the cognitive abilities of laboratory animals and their relation to morphological changes in the brain is rather contradictory. The aim of this study was to investigate cognitive functions and the dynamics of changes in morphological parameters of hippocampal mic...
Source: Radiation and Environmental Biophysics - October 4, 2023 Category: Physics Authors: S S Sorokina A E Malkov O M Rozanova E N Smirnova A E Shemyakov Source Type: research