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VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01021-8. Online ahead of print.ABSTRACTVascular endothelial growth factor (VEGF) is closely related to angiogenesis. Anticancer therapy by inhibiting VEGF signaling is well established. However, the role of VEGF in cell-cell communication during the response to ionizing radiation is not well understood. Here, we examined the role of VEGF on radiosensitivity of cells. The addition of recombinant VEGF (rVEGF) on cultured rat C6 glioma cells showed a radioprotective effects on X-ray irradiation and reduced oxidative stress. These effects were also observed by endoge...
Source: Radiation and Environmental Biophysics - March 21, 2023 Category: Physics Authors: Genro Kashino Shinko Kobashigawa Aoki Uchikoshi Yuki Tamari Source Type: research

Assessment of X-ray shielding properties of polystyrene incorporated with different nano-sizes of PbO
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01017-4. Online ahead of print.ABSTRACTPbO (lead oxide) particles with different sizes were incorporated into polystyrene (PS) with various weight fractions (0, 10, 15, 25, 35%). These novel PS/PbO nano-composites were produced by roll mill mixing and compressing molding techniques and then investigated for radiation attenuation of X-rays (N-series/ISO 4037) typically used in radiology. Properties of the PbO particles were studied by X-ray diffraction (XRD). Filler dispersion and elemental composition of the prepared nano-composites were characterized using scann...
Source: Radiation and Environmental Biophysics - March 20, 2023 Category: Physics Authors: Ahmad Firas Osman Hanna El Balaa Omar El Samad Ramadan Awad Mohamed S Badawi Source Type: research

Assessment of X-ray shielding properties of polystyrene incorporated with different nano-sizes of PbO
Radiat Environ Biophys. 2023 Mar 20. doi: 10.1007/s00411-023-01017-4. Online ahead of print.ABSTRACTPbO (lead oxide) particles with different sizes were incorporated into polystyrene (PS) with various weight fractions (0, 10, 15, 25, 35%). These novel PS/PbO nano-composites were produced by roll mill mixing and compressing molding techniques and then investigated for radiation attenuation of X-rays (N-series/ISO 4037) typically used in radiology. Properties of the PbO particles were studied by X-ray diffraction (XRD). Filler dispersion and elemental composition of the prepared nano-composites were characterized using scann...
Source: Radiation and Environmental Biophysics - March 20, 2023 Category: Physics Authors: Ahmad Firas Osman Hanna El Balaa Omar El Samad Ramadan Awad Mohamed S Badawi Source Type: research