The Effect of Head-Out Aquatic Exercise on Arterial Stiffness in Middle-Aged and Elderly People
Aquatic exercise is ideal for older adults because it mitigates weight-bearing stress. However, the effect of head-out aquatic exercise on arterial stiffness, a strong future cardiovascular disease (CVD) risk, remains unclear. We determined whether head-out aquatic exercise would mitigate arterial stiffness in middle-aged and elderly people. In 25 middle-aged and older people (9 men, mean age 64 ± 8 years), blood pressure (BP) and brachial-ankle pulse wave velocity (baPWV) were measured before and after a supervised aquatic exercise training program (60 min, 1 session/week, 14 sessions) which mainly consisted of walking, ...
Source: Pulse - April 15, 2019 Category: Cardiology Source Type: research
Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases
Genome-wide association studies (GWAS) have greatly expanded our understanding of the genetic architecture of cardiovascular diseases in the past decade. They have revealed hundreds of suggestive genetic loci that replicate known biological candidate genes and indicate the existence of a previously unsuspected new biology relevant to cardiovascular disorders. These data have been used successfully to create genetic risk scores that may improve risk prediction and the identification of susceptive individuals. Furthermore, these GWAS-identified novel pathways may herald a new era of novel drug development and stratification ...
Source: Pulse - February 5, 2019 Category: Cardiology Source Type: research
Cuff-Based Oscillometric Measurements of Central Hemodynamics: Factors Influencing Central Augmentation Pressure in Normotensive Japanese Individuals
Conclusions: Age, sex, and height influenced central AP, as assessed using the Mobil-O-Graph. Age-related increase in central AP was observed in normotensive Japanese individuals. Brachial cuff-based waveform recordings using the Mobil-O-Graph are feasible for the estimation of central AP in the Asian population.Pulse 2018;6:161 –168 (Source: Pulse)
Source: Pulse - January 31, 2019 Category: Cardiology Source Type: research
Association of Hemoglobin and Blood Pressure in a Chinese Community-Dwelling Population
This study investigated the relationship between hemoglobin (Hb) level and blood pressure in a Chinese community-dwelling population with normal glucose metabolism. Hb, fasting plasma glucose, glycated Hb A1c, hepatic and renal function, lipid, electrolytes, and anthropometric parameters were measured. Hb level was found to be positively correlated with systolic (SBP;r = 0.075,p #x3c; 0.001) and diastolic (DBP;r = 0.272,p #x3c; 0.001) blood pressure in the cohort. The relationship was not affected by age, BMI, serum creatinine (Cr), and low-density lipoprotein (LDL) in both males and females. Multivariate stepwise regressi...
Source: Pulse - November 28, 2018 Category: Cardiology Source Type: research
Urinary Metabolites and Their Link with Premature Arterial Stiffness in Black Boys: The ASOS Study
Conclusion: Our study is the first to discover the associations of pulse wave velocity with β-alanine, 1-methylhistidine, and L-proline in children from South Africa, which may suggest potential early compromise in cardiac protective metabolic pathways in black boys as young as 6 years of age.Pulse 2018;6:144 –153 (Source: Pulse)
Source: Pulse - August 17, 2018 Category: Cardiology Source Type: research
Renal Sympathetic Denervation in Patients with Resistant Hypertension: A Feasibility Study
Conclusion: The Iberis system is safe and effective in patients for the treatment of resistant hypertension. Furthermore, our results suggest that we can estimate the effect of RDN in the long term at the 1-month follow-up point using the 24-h SBP.Pulse 2018;6:137 –143 (Source: Pulse)
Source: Pulse - July 25, 2018 Category: Cardiology Source Type: research
Comparative Assessment of Cutoffs for the Cardio-Ankle Vascular Index and Brachial-Ankle Pulse Wave Velocity in a Nationwide Registry: A Cardiovascular Prognostic Coupling Study
Pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI) are measurements of arterial stiffness and are widely used as indices of arteriosclerosis. In Japan, brachial-ankle PWV (baPWV) is generally used to measure PWV, and while the reference value for this parameter is specified in Japanese guidelines for the noninvasive vascular function test, the CAVI reference value has not been standardized. We measured CAVI in 4,545 patients with at least one cardiovascular risk factor, and baPWV in 1,737 of these 4,545 patients on the same day as a part of an ongoing nationwide registry. The association between CAVI and baPW...
Source: Pulse - July 24, 2018 Category: Cardiology Source Type: research
Obstructive Sleep Apnea Is Closely Related to Cardiovascular Risk Factors, but Not to Clinical Recurrence of Atrial Fibrillation after Catheter Ablation: An Analysis of Atrial Fibrillation Patients
Conclusion: This study shows that the severity of OSA is not associated with the recurrence of AF after catheter ablation in Korean patients. Treatment of OSA for the sole indication of lowering AF recurrence may need to be reconsidered.Pulse 2018;6:103 –111 (Source: Pulse)
Source: Pulse - July 18, 2018 Category: Cardiology Source Type: research
Methods of Blood Pressure Assessment Used in Milestone Hypertension Trials
In the present review, we summarized the blood pressure (BP) measurement protocols of contemporary outcome trials in hypertension. In all these trials, clinic BP was used for the diagnosis and therapeutic monitoring of hypertension. In most trials, BP was measured in the sitting position with mercury sphygmomanometers or automated electronic BP monitors by trained observers. BP readings were taken on each occasion at least twice with a 30-to-60-s interval after 5 min of rest. Details regarding the arm side, cuff size, and the timing of BP measurement were infrequently reported. If clinic BP continues being used in future h...
Source: Pulse - July 18, 2018 Category: Cardiology Source Type: research
Dietary Sodium Intake and Serum Uric Acid: A Mini-Review
The aim of the present review is to summarize recent studies on the relationship between dietary sodium intake and serum uric acid concentration. In short-term dietary sodium intervention studies, including a recent further analysis of a previously published trial, high dietary sodium intake (200 mmol/day), compared with a low sodium diet (20 –60 mmol/day), resulted in a significant reduction in serum uric acid, being approximately 20–60 μmol/L. This finding, though consistent across short-term studies, is in contradiction to the long-term observational evidence on the relationship between dietary sodium intake and se...
Source: Pulse - July 18, 2018 Category: Cardiology Source Type: research
The Pulse of Asia 2018 Kyoto
Pulse 2018;6:32 –97 (Source: Pulse)
Source: Pulse - May 29, 2018 Category: Cardiology Source Type: research
Evaluation of Central Blood Pressure in an Asian Population: Comparison between Brachial Oscillometry and Radial Tonometry Methods
Conclusion: Central SBP estimated using brachial oscillometry was similar to that estimated from radial tonometry in a Japanese population.Pulse 2018;6:98 –102 (Source: Pulse)
Source: Pulse - May 29, 2018 Category: Cardiology Source Type: research
High-Intensity Statin Therapy Is “Too Much,” Thus Not Indicated for Very Elderly Patients
Conclusion: The efficacy of statins in LDL reduction was similar between the elderly and very elderly population. However, the benefit of moderate- to high-intensity statins is limited considering potential ADR. Therefore, the stepwise intensification of statin therapy might be necessary for the very elderly in spite of the higher cardiovascular risk.Pulse 2018;6:19 –31 (Source: Pulse)
Source: Pulse - April 12, 2018 Category: Cardiology Source Type: research
Erratum
Pulse 2017;5:6 –6 (Source: Pulse)
Source: Pulse - March 2, 2018 Category: Cardiology Source Type: research
Contents Vol. 5
Pulse 2017;5:I –III (Source: Pulse)
Source: Pulse - March 2, 2018 Category: Cardiology Source Type: research
