Risk Associated with Pulse Pressure on Out-of-Office Blood Pressure Measurement
Background: Longitudinal studies have demonstrated that the risk of cardiovascular disease increases with pulse pressure (PP). However, PP remains an elusive cardiovascular risk factor with findings being inconsistent between studies. The 2013 ESH/ESC guideline proposed that PP is useful in stratification and suggested a threshold of 60 mm Hg, which is 10 mm Hg higher compared to that in the 2007 guideline; however, no justification for this increase was provided. Methodology: Published thresholds of PP are based on office blood pressure measurement and often on arbitrary categorical analyses. In the International Database...
Source: Pulse - November 20, 2014 Category: Cardiology Source Type: research

Hypertensive Vasculopathy
An exclusive interview by Prof. Jeong Bae Park conducted with Dr. Rhian M. Touyz in Seoul while she was visiting for the Korean Society of Hypertension, May 10, 2014. In this interview, Dr. Touyz explains and describes hypertensive vasculopathy.Pulse 2014;2:38-41 (Source: Pulse)
Source: Pulse - November 13, 2014 Category: Cardiology Source Type: research

Pulse Pressure Is Useful for Determining the Choice of Antihypertensive Drugs in Postmenopausal Women
Objective: To assess the efficacy of various classes of antihypertensive drugs in postmenopausal women with hypertension using pulse pressure (PP) as an index. Patients and Methods: Selected women were required to be naturally menopausal for at least 1 year but not more than 5 years past their menstrual period. Exclusion criteria were a history of preeclampsia or eclampsia, a severe illness such as myocardial infarction or stroke within 6 months, the use of estrogens or progestins within 3 months, proteinuric nephropathy, and surgically induced menopause. There were 114 women who participated in this study after having giv...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Exercise Hypertension
Irrespective of apparent ‘normal' resting blood pressure (BP), some individuals may experience an excessive elevation in BP with exercise (i.e. systolic BP ≥210 mm Hg in men or ≥190 mm Hg in women or diastolic BP ≥110 mm Hg in men or women), a condition termed exercise hypertension or a ‘hypertensive response to exercise' (HRE). An HRE is a relatively common condition that is identified during standard exercise stress testing; however, due to a lack of information with respect to the clinical ramifications of an HRE, little value is usually placed on such a finding. In this review, we discuss both the clinical im...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

The Efficacy of Fimasartan for Cardiovascular Events and Metabolic Syndrome (K-MetS Study): Rationale, Design and Participant Characteristics
Fimasartan, the eighth angiotensin receptor blocker, was launched in March 2011 and was found to have an excellent efficacy and safety profile in a large cross-sectional population study [Safety and Efficacy of Fimasartan in Patients with Arterial Hypertension (Safe-KanArb); Park et al.: Am J Cardiovasc Drugs 2013;13:47-56]. However, there is no long-term study to evaluate its efficacy for major adverse cardiovascular events (MACE) and other effects. The purpose of this study (K-MetS study) was to evaluate whether the early reduction of blood pressure (BP) and/or correction of metabolic derangements with fimasartan will af...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Editorial
Pulse 2013;1:186-187 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

The Pulse of Asia. June 12-13, 2014, Athens, Greece: Abstracts
Pulse 2013;1:189-233 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Contents Vol. 1, 2014
Pulse 2013;1:I-IV (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Gender Difference in Arterial Stiffness in a Multicenter Cross-Sectional Study: The Korean Arterial Aging Study (KAAS)
In conclusion, arterial stiffness is mainly determined by sex, age, and blood pressure. Markers of arterial stiffness differ between men and women. Dyslipidemia and glucose contribute to a modest increase in arterial stiffness only in women. Therefore, the arteries of women may be more vulnerable to CV risk factors than those of men.Pulse 2014;2:11-17 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Role of Pulse Wave Velocity in Patients with Chronic Kidney Disease Stages 3-5 on Long-Term Follow-Up
Conclusion: With moderate progression of renal dysfunction and under well-controlled blood pressure, peripheral but not central arterial stiffness is possibly one of the strongest predictors of CVD in patients with CKD stages 3-5.Pulse 2014;2:1-10 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Common Carotid Artery Stiffness Is Associated with Left Ventricular Structure and Function and Predicts First Hospitalization for Acute Heart Failure
Conclusions: In patients at risk for heart failure, CCA stiffness was significantly associated with LV structure and function independently of cf-PWV. In addition, CCA stiffness but not cf-PWV predicted first AHF.Pulse 2014;2:18-28 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Decline of Renal Function and Progression of Left Ventricular Hypertrophy Are Independently Determined in Chronic Kidney Disease Stages 3-5
Conclusion: Worsening of renal dysfunction is not solely dependent on hemodynamics. Other factors might be involved in a complex manner.Pulse 2014;2:29-37 (Source: Pulse)
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research