Comment on the Paper by Cauwenberghs and Kuznetsova Entitled ‘Determinants and Prognostic Significance of the Renal Resistive Index'
Pulse 2015;3:179-181 (Source: Pulse)
Source: Pulse - January 12, 2016 Category: Cardiology Source Type: research
Determinants and Prognostic Significance of the Renal Resistive Index
Conclusion: Published studies on RRI imply that the interaction between the systemic hemodynamics and peripheral circulation in the kidney is a complex physiological phenomenon. In addition to renal vascular properties, the central hemodynamic factors significantly influence the intrarenal arterial Doppler waveform patterns. Previous research also suggested an important role of the RRI for the evaluation of renal target organ damage, particularly in patients with increased pulsatility of the intrarenal blood flow.Pulse 2015;3:172-178 (Source: Pulse)
Source: Pulse - January 12, 2016 Category: Cardiology Source Type: research
Arterial Stiffness Gradient
Background: Aortic stiffness is a strong predictor of cardiovascular mortality in various clinical conditions. The aim of this review is to focus on the arterial stiffness gradient, to discuss the integrated role of medium-sized muscular conduit arteries in the regulation of pulsatile pressure and organ perfusion and to provide a rationale for integrating their mechanical properties into risk prediction. Summary: The physiological arterial stiffness gradient results from a higher degree of vascular stiffness as the distance from the heart increases, creating multiple reflective sites and attenuating the pulsatile nature of...
Source: Pulse - September 1, 2015 Category: Cardiology Source Type: research
Model for Predicting Cardiovascular Disease: Insights from a Korean Cardiovascular Risk Model
The profile and prevalence of risk factors in cardiovascular disease (CVD) are different between Western and Asian populations. In the guidelines, tailored approaches following risk stratification based on CVD risk models are recommended for the primary prevention of CVD in asymptomatic subjects. However, current risk models for predicting CVD in Asian populations are limited. A recent study of a large cohort of asymptomatic Korean individuals developed a CVD risk model to predict global cardiovascular risk that showed good performance in predicting cardiovascular events. This model may be useful for the primary prevention...
Source: Pulse - August 25, 2015 Category: Cardiology Source Type: research
Lipoprotein(a) and Arterial Stiffness Parameters
Conclusion: The present review indicates a positive association between Lp(a) and arterial stiffness, as assessed by PWV and CAVI. To definitively establish these findings, there is a need for further prospective outcome studies that simultaneously measure Lp(a) and the oxidative form of Lp(a) (as a pathological marker) as well as PWV and CAVI.Pulse 2015;3:148-152 (Source: Pulse)
Source: Pulse - August 24, 2015 Category: Cardiology Source Type: research
Vasculopathy of Aging and the Revised Cardiovascular Continuum
There have been attempts to explain the process of developments in overt cardiovascular disease, resulting in the presentation of the classic cardiovascular disease continuum and the aging cardiovascular continuum. Although the starting points of these two continua are different, they meet in the midstream of the cycle and reach a consensus at the end of the process. The announcement of the aging cardiovascular continuum made both continua complete, explaining the cardiovascular events in patients without atherosclerotic cardiovascular disease with aging. Impairment of the vascular structure by pulse wave and reflected wav...
Source: Pulse - August 19, 2015 Category: Cardiology Source Type: research
Weight Loss, Dietary Intake and Pulse Wave Velocity
We have recently conducted a meta-analysis to determine the effect of weight loss achieved by an energy-restricted diet with or without exercise, anti-obesity drugs or bariatric surgery on pulse wave velocity (PWV) measured at all arterial segments. Twenty studies, including 1,259 participants, showed that modest weight loss (8% of the initial body weight) caused a reduction in PWV measured at all arterial segments. However, due to the poor methodological design of the included studies, the results of this meta-analysis can only be regarded as hypothesis generating and highlight the need for further research in this area. ...
Source: Pulse - July 18, 2015 Category: Cardiology Source Type: research
The Role of Monitoring Arterial Stiffness with Cardio-Ankle Vascular Index in the Control of Lifestyle-Related Diseases
Arteriosclerosis is a major contributor to cardiovascular diseases. One of the difficulties in controlling those diseases is the lack of a suitable indicator of arteriosclerosis or arterial injury in routine clinical practice. Arterial stiffness was supposed to be one of the monitoring indexes of arteriosclerosis. Cardio-ankle vascular index (CAVI) is reflecting the stiffness of the arterial tree from the origin of the aorta to the ankle, and one of the features of CAVI is independency from blood pressure at a measuring time. When doxazosin, an α1-adrenergic blocker, was administered, CAVI decreased, indicating that arter...
Source: Pulse - June 19, 2015 Category: Cardiology Source Type: research
Cardiopulmonary Exercise Test in Patients with Hypertension: Focused on Hypertensive Response to Exercise
The cardiopulmonary exercise test (CPET) provides integrative exercise responses including the cardiovascular, pulmonary and skeletal muscle systems. It can be used for the identification of myocardial ischemia, evaluation of exercise capacity and tolerance, and the assessment of chronotropic competence or arrhythmias with the addition of ventilatory and gas exchange measurement information. Among them, hypertensive response to exercise (HRE) is known to be related with higher risk of future heart failure and cardiovascular events in patients with hypertension. Proposed underlying mechanisms of HRE can be found in ventricu...
Source: Pulse - June 6, 2015 Category: Cardiology Source Type: research
Brachial-Ankle Pulse Wave Velocity: Myths, Misconceptions, and Realities
A variety of techniques to evaluate central arterial stiffness have been developed and introduced. None of these techniques, however, have been implemented widely in regular clinical settings, except for brachial-ankle pulse wave velocity (baPWV). The most prominent procedural advantage of baPWV is its ease of use, since it only requires the wrapping of blood pressure cuffs on the 4 extremities. There is mounting evidence indicating the ability of baPWV to predict the risk of future cardiovascular events and total mortality. Additionally, the guidelines for the management of hypertension in Japan recommended the measuremen...
Source: Pulse - June 3, 2015 Category: Cardiology Source Type: research
Prognostic Significance of Regional Arterial Stiffness for Stroke in Hypertension
Background: Hypertension is strongly associated with cardiovascular disease. It has been reported that arterial stiffness is related to cardiovascular mortality and morbidity in hypertensive patients and that the physiological evaluation of arterial stiffness may assist clinicians in the early detection of atherosclerosis. Summary: It has been demonstrated that increased arterial stiffness is an independent predictor of cardiovascular disease, including stroke. Arterial stiffness is associated with structural changes in the brain. However, the stiffness responses of muscular arteries are different from those of elastic art...
Source: Pulse - May 27, 2015 Category: Cardiology Source Type: research
Contents Vol. 2, 2014
Pulse 2014;2:I-IV (Source: Pulse)
Source: Pulse - May 20, 2015 Category: Cardiology Source Type: research
Arterial Stiffening and Clinical Outcomes in Dialysis Patients
Cardiovascular disease (CVD) is an important cause of morbidity and mortality in dialysis patients. Brachial-ankle pulse wave velocity (baPWV) is more efficient to handily assess arteriosclerosis than aortic PWV. The cardio-ankle vascular index (CAVI) is also a novel blood pressure-independent arterial stiffness parameter. In dialysis patients, both baPWV and CAVI are increased compared to general subjects. Several studies have demonstrated that increased baPWV is associated with carotid atherosclerosis and diastolic left ventricular dysfunction in hemodialysis (HD) patients. In addition, higher baPWV is related to all-cau...
Source: Pulse - May 13, 2015 Category: Cardiology Source Type: research
Lung Disease and Hypertension
Chronic obstructive pulmonary disease (COPD) patients are at a high risk of developing cardiovascular diseases. Airflow limitation is a predictor of future risks of hypertension and cardiovascular events. COPD is now understood as a systemic inflammatory disease, with the focus on inflammation of the lungs. An association between inflammation and sympathetic overactivity has also been reported. In this article, we review the association between chronic lung disease and the risks of hypertension, cardiovascular morbidity, the underlying mechanisms, and the therapeutic approach to hypertension and cardiovascular diseases in ...
Source: Pulse - May 6, 2015 Category: Cardiology Source Type: research
The Pulse of Asia, May 22-23, 2015, Shanghai, China: Abstracts
Pulse 2015;3:48-87 (Source: Pulse)
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research
