The Ten-Year History of the Asklepios Study
The Asklepios study started 10 years ago when 2,500 subjects were screened between 2002 and 2004. And all of the 90+ publications we have for the moment are from those cross-sectional data. This is called round 1. Since 2011, in round 2, all of those patients have started to come back for a 10-year follow-up. At this moment, approximately 1,750 of those patients have been seen. The patients were followed by general practitioners (GP), and the GP again provided the information about what has happened with the medical status in the past 10 years including drug therapy: not only the drugs that they are taking at the moment we...
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Key Points of the Japanese Society of Hypertension Guidelines for the Management of Hypertension in 2014
The Japanese Society of Hypertension (JSH) published the new JSH guidelines for the management of hypertension in 2014, which is the revision of the JSH guidelines of 2009. The primary objective of the guideline is to provide physicians the standard treatment strategy of hypertension to prevent the hypertension-related target organ damage and cardiovascular events. The management of hypertension should be performed in hypertensive patients with a blood pressure of ≥140/90 mm Hg. As Asians have a higher prevalence of stroke than of coronary artery disease and stroke is more steeply associated with the level of blood press...
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

The Novelty of the 2015 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension
The prevalence rate of hypertension in Asian countries grows faster than in other parts of the world, where stroke exceeds coronary heart disease in causing morbidities and mortalities. The optimal management of hypertension is therefore an especially important task in Asia. In a transparent and rigorous guideline development process, the most updated information available on the management of hypertension was summarized in the 2015 Taiwan Society of Cardiology (TSOC)/Taiwan Hypertension Society (TSH) hypertension guideline. In contradiction with the ESH/ESH joint hypertension guidelines and the 2014 Joint National Committ...
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

The Korean Society of Hypertension Guidelines for the Management of Hypertension in 2013: Its Essentials and Key Points
The Korean Society of Hypertension published new guidelines for the management of hypertension in 2013 which fully revised the first Korean hypertension treatment guideline published in 2004. Due to shortage of Korean data, the Committee decided to establish the guideline in the form of an ‘adaptation' of the recently released guidelines. The prevalence of hypertension was 28.5% in the recent Korean National Health and Nutrition Examination Survey in 2011, and the awareness, treatment, and control rates are generally improving. However, the risks for cerebrovascular disease and coronary artery disease which are attributa...
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Chinese Hypertension Guidelines
According to the 4th National Nutrition and Health Survey in 2002, the prevalence of hypertension in China was 18.8%. Although there are no recent updated nationwide data, it is believed that the prevalence of hypertension has increased substantially in the past decade up to more than 200 million hypertensive patients in the populous country of China. To fight against the growing risk of hypertension, three Chinese hypertension guidelines were compiled in the past two decades, in 1999, 2005, and 2011. The current guidance document for the management of hypertension was named ‘2010 Chinese hypertension guideline', but it ...
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Asian Guidelines on Hypertension
Pulse 2015;3:12-13 (Source: Pulse)
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Hypertension Guidelines: Timely New Initiatives from East Asia
Pulse 2015;3:1-3 (Source: Pulse)
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Lifestyle Factors and Coronary Artery Calcification
This article briefly reviews whether lifestyle factors relate to subclinical atherosclerosis as assessed by coronary artery calcification in asymptomatic individuals.Pulse 2014;2:95-102 (Source: Pulse)
Source: Pulse - March 11, 2015 Category: Cardiology Source Type: research

Clinical Considerations for the Association between Vascular Damage and Chronic Kidney Disease
Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease. Recently, noninvasive and simple morphological and functional methods have been introduced to assess atherosclerotic vascular damage. This review describes the association of CKD with vascular damage as assessed by these methods. Carotid intima-media thickness (IMT) and coronary artery calcium score (CACS) are morphological parameters of vascular damage, and an ankle-brachial index (ABI) (Source: Pulse)
Source: Pulse - February 26, 2015 Category: Cardiology Source Type: research

Arterial Stiffness in Children: Pediatric Measurement and Considerations
Conclusions: The measurement of arterial stiffness in children is feasible and, under controlled conditions, can give accurate information about the underlying state of the arteries. This potentially adds valuable information about the functionality of the cardiovascular system in children with a variety of chronic diseases well beyond that of the brachial artery blood pressure.Pulse 2014;2:69-80 (Source: Pulse)
Source: Pulse - February 17, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: Is the Future Now
Pulse 2014;2:63-68 (Source: Pulse)
Source: Pulse - February 3, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: A Window into the Future
The aorta has limited ability to accommodate increasing body size by remodeling. The dramatic rise in pediatric obesity threatens to overwhelm this intrinsic remodeling program and lead to abnormal aortic function. As hypothesized, pulse pressure, as an index of aortic function, has indeed risen dramatically in parallel with the rise of pediatric obesity, while at the same time mean arterial pressure, as an index of small resistance artery function, has fallen. These divergent large-artery-versus-small-artery indices may combine to explain the counterintuitive decrease in systolic blood pressure in children and adults duri...
Source: Pulse - February 3, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: Is the Future Now?
Pulse 2014;2:63-68 (Source: Pulse)
Source: Pulse - February 2, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: A Window into the Future?
The aorta has limited ability to accommodate increasing body size by remodeling. The dramatic rise in pediatric obesity threatens to overwhelm this intrinsic remodeling program and lead to abnormal aortic function. As hypothesized, pulse pressure, as an index of aortic function, has indeed risen dramatically in parallel with the rise of pediatric obesity, while at the same time mean arterial pressure, as an index of small resistance artery function, has fallen. These divergent large-artery-versus-small-artery indices may combine to explain the counterintuitive decrease in systolic blood pressure in children and adults duri...
Source: Pulse - February 2, 2015 Category: Cardiology Source Type: research

Noninvasive and Invasive Assessments of the Functional Significance of Intermediate Coronary Artery Stenosis: Is This a Matter of Right or Wrong?
Coronary computed tomographic angiography (cCTA) has emerged in recent years as a noninvasive modality to evaluate coronary artery disease. Many studies have revealed the excellent diagnostic accuracy of cCTA when compared with invasive coronary angiography (ICA) or intravascular ultrasound (IVUS). It is generally accepted that the functional significance of coronary artery stenosis is important to make treatment decisions; however, cCTA, ICA, and IVUS are limited in the ability to determine the physiologic significance of coronary stenosis. The FIGURE-OUT study compared the noninvasive and invasive assessment of the funct...
Source: Pulse - December 16, 2014 Category: Cardiology Source Type: research