A Promotion Role of MIR31 in the Process of Vocal Fold Wound Healing
In this study, we first constructed a literature-based pathway to examine both the positive and negative effects of MIR31 on wound healing. We then conducted animal experiments on 20 rats to investigate MIR31 expression at different time points (1, 4, and 8 weeks) after vocal fold injury. Co-expression analysis and pathway analysis were performed to explore the potential function of MIR31 in VFWH. The literature-based pathway suggested that MIR31 could both impede and promote the wound healing process by regulating 14 and 47 wound healing upstream regulators, respectively. However, the rat experiment indicated that MIR31 e...
Source: PPAR Research - August 17, 2023 Category: Genetics & Stem Cells Authors: Haizhou Wang Wen Xu Source Type: research
