New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
CONCLUSIONS: TGS 121, 404, and 702 present anti-tumor potential and are an attractive therapeutic option for colorectal cancer.PMID:38082190 | DOI:10.1007/s43440-023-00558-1 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 11, 2023 Category: Drugs & Pharmacology Authors: Jakub W łodarczyk Julia Krajewska Marcin Talar Łukasz Szeleszczuk Agata Gurba Szymon Lipiec Przemys ław Taciak Remigiusz Szczepaniak Izabela M łynarczuk-Biały Jakub Fichna Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

Impact of metformin on hypothalamic-pituitary-thyroid axis activity in women with autoimmune and non-autoimmune subclinical hypothyroidism: a pilot study
CONCLUSIONS: The obtained results suggest that, despite differences in thyroid output, the impact of metformin on TSH levels is similar in hypothyroid women with and without thyroid autoimmunity.PMID:38051473 | DOI:10.1007/s43440-023-00556-3 (Source: Pharmacological Reports)
Source: Pharmacological Reports - December 5, 2023 Category: Drugs & Pharmacology Authors: Robert Krysiak Karolina Kowalcze Bogus ław Okopień Source Type: research

AM1172 (a hydrolysis-resistant endocannabinoid analog that inhibits anandamide cellular uptake) reduces the viability of the various melanoma cells, but it exerts significant cytotoxic effects on healthy cells: an in vitro study based on isobolographic analysis
CONCLUSIONS: AM1172 cannot be used separately as a chemotherapeutic drug, but it can be combined with PACX, DOCX, MTX, and CDDP, offering additive interactions in terms of the anti-proliferative effects in various malignant melanoma cell lines.PMID:38019413 | DOI:10.1007/s43440-023-00557-2 (Source: Pharmacological Reports)
Source: Pharmacological Reports - November 29, 2023 Category: Drugs & Pharmacology Authors: Pawe ł Marzęda Paula Wr óblewska-Łuczka Magdalena Florek- Łuszczki Agnieszka G óralczyk Jarogniew J Łuszczki Source Type: research

AM1172 (a hydrolysis-resistant endocannabinoid analog that inhibits anandamide cellular uptake) reduces the viability of the various melanoma cells, but it exerts significant cytotoxic effects on healthy cells: an in vitro study based on isobolographic analysis
CONCLUSIONS: AM1172 cannot be used separately as a chemotherapeutic drug, but it can be combined with PACX, DOCX, MTX, and CDDP, offering additive interactions in terms of the anti-proliferative effects in various malignant melanoma cell lines.PMID:38019413 | DOI:10.1007/s43440-023-00557-2 (Source: Pharmacological Reports)
Source: Pharmacological Reports - November 29, 2023 Category: Drugs & Pharmacology Authors: Pawe ł Marzęda Paula Wr óblewska-Łuczka Magdalena Florek- Łuszczki Agnieszka G óralczyk Jarogniew J Łuszczki Source Type: research

AM1172 (a hydrolysis-resistant endocannabinoid analog that inhibits anandamide cellular uptake) reduces the viability of the various melanoma cells, but it exerts significant cytotoxic effects on healthy cells: an in vitro study based on isobolographic analysis
CONCLUSIONS: AM1172 cannot be used separately as a chemotherapeutic drug, but it can be combined with PACX, DOCX, MTX, and CDDP, offering additive interactions in terms of the anti-proliferative effects in various malignant melanoma cell lines.PMID:38019413 | DOI:10.1007/s43440-023-00557-2 (Source: Pharmacological Reports)
Source: Pharmacological Reports - November 29, 2023 Category: Drugs & Pharmacology Authors: Pawe ł Marzęda Paula Wr óblewska-Łuczka Magdalena Florek- Łuszczki Agnieszka G óralczyk Jarogniew J Łuszczki Source Type: research