Transcranial Doppler Ultrasonography in Children With Acute Liver Failure and Severe Hepatic Encephalopathy
OBJECTIVES: To report our single-center use of transcranial Doppler (TCD) for noninvasive neuromonitoring in pediatric patients with acute liver failure (ALF). DESIGN: Retrospective cohort from January 2016 to June 2019. SETTING: PICU in Bicêtre Hospital, Assistance Publique- Hôpitaux de Paris (AP-HP), a national referral center for pediatric liver transplantation. PATIENTS: Pediatric patients with severe ALF (prothrombin time (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Comparison of Laboratory and Hemodynamic Time Series Data Across Original, Alpha, and Delta Variants in Patients With Multisystem Inflammatory Syndrome in Children
OBJECTIVES: To compare the clinical, laboratory, and hemodynamic parameters during hospitalization for patients with multisystem inflammatory syndrome in children (MIS-C), across the Original/Alpha and the Delta variants of severe acute respiratory syndrome coronavirus 2 infection. DESIGN: Retrospective cohort study. SETTING: Single-center quaternary children’s hospital. PATIENTS: Children with MIS-C admitted from May 2020 to February 2021(Original and Alpha variant cohort) and August 2021 to November 2021 (Delta variant cohort). MEASUREMENTS AND MAIN RESULTS: Continuous vital sign measure...
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Online Clinical Investigation Source Type: research

Why Does Current Clinical Decision Support Frequently Fail to Support Clinical Decisions?*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Emotional Intelligence in the PICU: The Good News and the Bad*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Peripheral Vasopressors—Are We Avoiding the Central Issue Altogether?*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Reckoning With Redlining and Other Structural Barriers to Health of Critically Ill Children: Addressing Systemic Racism Will Require Shifting the Focus From Micro- to Macrolevel Analysis of Social Risks*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Late-Onset Neurologic Dysfunction in Pediatric Sepsis—What Brains Might Learn From Kidneys and Persistent Acute Kidney Injury*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

The Post-PICU Growth Curve*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

Writing for PCCM: Instructions for Authors
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: PCCM Notes, Methods, and Statistics Source Type: research

Variations in Demonstrated Emotional Intelligence: Trainee to Experienced Faculty Member*
CONCLUSIONS: This study provides the first characterization of EI competencies among trainees and faculty members using a validated multirater assessment tool. The descriptions of physician EI, based on years of experience, are an important piece of the foundation for future explorations into the advancement of physician EI and effective leadership. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Brief Report Source Type: research

Association of Pathogen Type With Outcomes of Children Encountering Community-Acquired Pediatric Septic Shock
CONCLUSIONS: This secondary analysis of the LAPSE database identified no statistically significant association of pathogen type with composite mortality and morbidity outcomes. However, pathogen type may be associated with PICU resources employed to treat sepsis organ dysfunction. Ultimately, pediatric septic shock was frequently associated with adverse patient-centered, clinically meaningful outcomes regardless of infectious disease pathogen type. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Clinical Investigations Source Type: research

Peripheral and Central/Intraosseous Vasoactive Infusions During and After Pediatric Critical Care Transport: Retrospective Cohort Study of Extravasation Injury*
CONCLUSIONS: During pediatric critical care transport, we did not find a difference in prevalence of adverse events following the administration of vasoactive drugs via peripheral venous catheters or via central venous and intraosseous catheters. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Clinical Investigations Source Type: research

Peripheral Vasoactive Administration in Critically Ill Children With Shock: A Single-Center Retrospective Cohort Study*
CONCLUSIONS: In our experience, peripheral venous catheters can be used for vasoactive administration. In our series, the upper limit of the 95% CI for extravasation is approximately 1-in-30, meaning that this route may be an appropriate option while evaluating the need for central access, particularly in patients with low illness severity. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Clinical Investigations Source Type: research

Geospatial Analysis of Social Determinants of Health Identifies Neighborhood Hot Spots Associated With Pediatric Intensive Care Use for Acute Respiratory Failure Requiring Mechanical Ventilation*
CONCLUSIONS: Social determinants of health identified by geospatial analyses are associated with acute respiratory failure requiring invasive mechanical ventilation in critically ill children. Interventions addressing the neighborhood social vulnerability and child opportunity are needed to decrease disparities in intensive care admissions for acute respiratory failure requiring mechanical ventilation. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Outcomes Associated With Timing of Neurologic Dysfunction Onset Relative to Pediatric Sepsis Recognition*
OBJECTIVES: To compare outcomes associated with timing—early versus late—of any neurologic dysfunction during pediatric sepsis. DESIGN: Secondary analysis of a cross-sectional point prevalence study. SETTING: A total of 128 PICUs in 26 countries. PATIENTS: Less than 18 years with severe sepsis on 5 separate days (2013–2014). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Patients were categorized as having either no neurologic dysfunction or neurologic dysfunction (i.e., present at or after sepsis recognition), which was defined as Glasgow Coma Scale score less than 5 and/o...
Source: Pediatric Critical Care Medicine - August 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research