Pediatric Chronic Critical Illness: Validation, Prevalence, and Impact in a Children’s Hospital
CONCLUSIONS: Pediatric chronic critical illness patients occupied more than one third of the ICU beds and have five times longer stay. This mounting load needs to be uniformly defined, addressed at regional and national levels, and considered in the current pandemic planning. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery: A Retrospective Multicenter Study
OBJECTIVES: We aimed to describe characteristics and operative outcomes from a multicenter cohort of infants who underwent repair of anomalous left coronary artery from the pulmonary artery. We also aimed to identify factors associated with major adverse cardiovascular events following anomalous left coronary artery from the pulmonary artery repair. DESIGN: Retrospective chart review. SETTING: Twenty-one tertiary-care referral centers. PATIENTS: Infants less than 365 days old who underwent anomalous left coronary artery from the pulmonary artery repair. INTERVENTIONS: None. MEASUREMENTS A...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study
OBJECTIVES: To characterize the pediatric super-refractory status epilepticus population by describing treatment variability in super-refractory status epilepticus patients and comparing relevant clinical characteristics, including outcomes, between super-refractory status epilepticus, and nonsuper-refractory status epilepticus patients. DESIGN: Retrospective cohort study with prospectively collected data between June 2011 and January 2019. SETTING: Seventeen academic hospitals in the United States. PATIENTS: We included patients 1 month to 21 years old presenting with convulsive refractory status ...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Continuous Renal-Replacement Therapy in Critically Ill Children: Practice Changes and Association With Outcome
This study was designed to evaluate practice changes and outcomes over a 10-year period in a large single-center PICU cohort that received continuous renal-replacement therapy. DESIGN: Retrospective study design. SETTING: A multidisciplinary tertiary PICU of a university-affiliated hospital in Guangzhou, China. PATIENTS: All critically ill children who were admitted to our PICU from January 2010 to December 2019 and received continuous renal-replacement therapy were included in this study. MEASUREMENTS AND MAIN RESULTS: A total of 289 patients were included in the study. Of the two study periods...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Left Heart Decompression on Extracorporeal Membrane Oxygenation Support and Cardiopulmonary Bypass
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online PCCM Concise Physiology Review Source Type: research

Collateral Damage*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Editorials Source Type: research

Restoring Justice: Affluence Should Not Determine Children’s Access to Critical Care Services*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Editorials Source Type: research

Causal Inference From Observational Data: It Is Complicated*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Editorials Source Type: research

Learning From an Association Analysis Using Propensity Scores
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: PCCM Notes, Methods, and Statistics Source Type: research

Association Between Anticholinergic Drug Burden and Adequacy of Enteral Nutrition in Critically Ill, Mechanically Ventilated Pediatric Patients
We examined the association between the anticholinergic burden of administered medications using the Anticholinergic Drug Scale and adequacy of enteral nutrition delivery. DESIGN: Secondary analysis of data from a previously characterized PICU cohort. SETTING: Multidisciplinary PICU in a quaternary academic medical center. PATIENTS: Younger than or equal to 18 years, on mechanical ventilation and received enteral nutrition within the first 3 days of PICU admission. MEASUREMENTS AND MAIN RESULTS: Daily Anticholinergic Drug Scale score, demographic data, and clinical data were obtained from the pr...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Brief Reports Source Type: research

Relationship Distress at Home and Burnout Among 254 Pediatric Intensive Care Nurses*
CONCLUSIONS: This study reflects the prevalence of relationship distress and its association with burnout and other practice and personal factors among PICU nurses. Nurses with high depersonalization experienced significantly higher distress in relationship satisfaction, and nurses who reported high personal satisfaction had significantly higher distress in relationship consensus. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Brief Reports Source Type: research

A Hard Learned Lesson on What It’s Like to Be a Patient
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: PCCM Narrative Source Type: research

Overall Health Following Pediatric Critical Illness: A Scoping Review of Instruments and Methodology
CONCLUSIONS: Overall health was commonly assessed post-PICU discharge, especially in the traumatic brain injury population, using a heterogenous array of measures. Evaluation and consensus are imperative to identify the most appropriate method to measure overall health with the goal of improving care efficacy and facilitating recovery across populations of critically ill children. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Review Article Source Type: research

ICU Admission in Children With Acute Lymphoblastic Leukemia in Sweden: Prevalence, Outcome, and Risk Factors
CONCLUSIONS: The need for intensive care in children with acute lymphoblastic leukemia, especially for children with T cell acute lymphoblastic leukemia and CNS leukemia, is high with most admissions occurring during early treatment. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Clinical Investigation Source Type: research

Outcomes of Catheter-Related Arterial and Venous Thrombosis After Enoxaparin Therapy in Neonates and Infants With Congenital Heart Disease
CONCLUSIONS: A high proportion of vascular catheter-related thrombi identified in infants with congenital heart disease resolve with enoxaparin treatment. In all patients with thrombosis, arterial versus venous thrombosis is associated with greater odds of resolution. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Cardiac Intensive Care Source Type: research