A Core Outcome Measurement Set for Pediatric Critical Care*
Conclusions: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research studies to characterize PICU survivorship and enable interventional studies to target long-term outcomes after critical illness. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - November 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Extracorporeal Membrane Oxygenation Outcomes in Children With Preexisting Neurologic Disorders or Neurofunctional Disability*
Conclusions: In this exploratory study using a multicenter pediatric ECMO registry, more than one third of children requiring ECMO support had pre-ECMO neurologic disorders or disability. However, pre-existing morbidities were not independently associated with mortality or unfavorable neurologic outcomes at hospital discharge after adjustment for diagnostic category and other covariates. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - November 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Moral Distress in the Italian PICUs: The Role of Individual and Organizational Factors*
Objectives: To assess the interplay between individual and organizational factors on moral distress in PICUs. Design: Cross-sectional, article-based survey administered between June and August 2017. Setting: Twenty-three Italian PICUs. Subjects: Of 874 eligible clinicians, 635 responded to the survey (75% response rate), and 612 correctly completed the survey. Clinicians were 74% female; 66% nurses and 34% physicians; and 51% had between 6 and 20 years of experience from graduation. Intervention: None. MEASUREMENTS AND MAIN RESULTS: Clinicians completed the “Italian Moral Distress S...
Source: Pediatric Critical Care Medicine - November 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Calcium Administration During Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest in Children With Heart Disease Is Associated With Worse Survival—A Report From the American Heart Association’s Get With The Guidelines-Resuscitation (GWTG-R) Registry*
Objectives: IV calcium administration during cardiopulmonary resuscitation (CPR) for pediatric in-hospital cardiac arrest (IHCA) is associated with worse survival. We evaluated survival to hospital discharge in children with heart disease (HD), where calcium is more frequently administered during CPR. Design: Retrospective study of a multicenter registry database. Setting: Data reported to the American Heart Association’s (AHA) Get With The Guidelines-Resuscitation registry. Patients: Children younger than 18 years with HD experiencing an index IHCA event requiring CPR between January 2000 and Ja...
Source: Pediatric Critical Care Medicine - November 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Editor’s Choice Articles for November
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - November 1, 2022 Category: Pediatrics Tags: Editor’s Choice Source Type: research

Online Abstract Translations
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Abstract Translations Source Type: research

The authors reply
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Correspondence Source Type: research

About PANDEM 2022 and “Rationale: Ketamine Appears to Be a Safe...”
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Correspondence Source Type: research

The Relevance of Airway Resistance in Children Requiring Mechanical Ventilatory Support
Objectives: To describe pulmonary resistance in children undergoing invasive mechanical ventilation (MV) for different causes. Design: A cross-sectional study. Setting: Two PICUs in the South region of Brazil. Patients: Children 1 month to 15 years old undergoing MV for more than 24 hours were included. We recorded ventilator variables and measured pulmonary mechanics (inspiratory and expiratory resistance, auto positive end-expiratory pressure [PEEP], and dynamic and static compliance) in the first 48 hours of MV. Interventions: Measurements of the respiratory mechanics variables during neu...
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Brief Report Source Type: research

Airway Bacterial Colonization, Biofilms and Blooms, and Acute Respiratory Infection
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Concise Clinical Science Review Source Type: research

Bivalirudin or Unfractionated Heparin for Anticoagulation in Pediatric Patients on Continuous Flow Ventricular Assist Device Support: Single-Center Retrospective Cohort Study
Conclusions: Use of bivalirudin for anticoagulation in patients on CF-VAD support was associated with lesser odds of hemorrhagic complications compared with use of UFH. Bivalirudin “washout” was successful in medical management of six of eight cases of possible pump thrombosis. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Lessons and Insights From the Implementation of the Cohort Model for a PICU: A Case Study Research
Conclusions: Our transition to a cohort PICU model offers lessons on impacts of PICU model changes on communities and teams. These theory-informed insights and implications can guide others undergoing similar transitions. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Weight-Based Versus Flat Dosing of Epinephrine During Cardiac Arrest in the PICU: A Multicenter Survey
Conclusions: The majority of PICUs surveyed report epinephrine dosing practices that are inconsistent with PALS guidelines. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Clinical Relevance of Adverse Pulmonary Outcomes Following Severe Bronchiolitis*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research

In Search of the Unbiased Truth: Peritoneal Dialysis After Cardiac Surgery in Infants*
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - October 1, 2022 Category: Pediatrics Tags: Editorials Source Type: research