Establishing Entrustable Professional Activities in Pediatric Cardiac Critical Care*
CONCLUSIONS: We generated a set of nine entrustable professional activities, which we believe can be broadly applied to any physician training in pediatric cardiac critical care, irrespective of individual training pathway. Next steps include incorporation of these entrustable professional activities into curriculum design and trainee assessment tools. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Brief Report Source Type: research

When Mission Is the Mission
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: PCCM Narrative Source Type: research

Executive Summary of Recommendations and Expert Consensus for Plasma and Platelet Transfusion Practice in Critically Ill Children: From the Transfusion and Anemia EXpertise Initiative—Control/Avoidance of Bleeding (TAXI-CAB)
CONCLUSIONS: The TAXI-CAB program provides expert-based consensus for pediatric intensivists for the administration of plasma and/or platelet transfusions in critically ill pediatric patients. There is a pressing need for primary research to provide more evidence to guide practitioners. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Executive Summary Source Type: research

Oxygenation Defects, Ventilatory Ratio, and Mechanical Power During Severe Pediatric Acute Respiratory Distress Syndrome: Longitudinal Time Sequence Analyses in a Single-Center Retrospective Cohort*
CONCLUSIONS: Mortality after severe pediatric acute respiratory distress syndrome is associated with the severity of organ dysfunction, oxygenation defects, and pulmonary metrics including dead space and theoretical mechanical energy load. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Temperature Management and Health-Related Quality of Life in Children 3 Years After Cardiac Arrest
OBJECTIVES: Therapeutic hypothermia minimizes neuronal injury in animal models of hypoxic-ischemic encephalopathy with greater effect when used sooner after the insult. Clinical trials generally showed limited benefit but are difficult to perform in a timely manner. In this clinical study, we evaluated the association between the use of hypothermia (or not) and health-related quality of life among survivors of pediatric cardiac arrest as well as overall mortality. DESIGN: Single-center, retrospectively identified cohort with prospective assessment of health-related quality of life. SETTING: PICU of a pedi...
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Assessment of a Situation Awareness Quality Improvement Intervention to Reduce Cardiac Arrests in the PICU
CONCLUSIONS: Interprofessional teams using shared situation awareness may reduce cardiopulmonary resuscitation events and, thereby, improve outcomes. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Editor’s Choice Articles for January
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - January 1, 2022 Category: Pediatrics Tags: Editor’s Choice Source Type: research

Online Abstract Translations: Erratum
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Erratum Source Type: research

Online Abstract Translations
No abstract available (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Abstract Translations Source Type: research

Application of Multiplex Polymerase Chain Reaction for Pathogen Identification and Antibiotic Use in Children With Respiratory Infections in a PICU
OBJECTIVES: To compare the pathogen identification rate and use of antibiotics before and after the implementation of multiplex polymerase chain reaction testing in children with respiratory infections in a PICU. DESIGN: Single-center, pre-post study. SETTING: PICU of Osaka Women’s and Children’s Hospital, Osaka, Japan. PATIENTS: Consecutive children with respiratory infections who were admitted to the PICU between December 2017 and November 2018 (premultiplex polymerase chain reaction period) and between March 2019 and February 2020 (postmultiplex polymerase chain reaction period). INTERVEN...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Characteristics and Outcomes of Children With Necrotizing Pneumonia
CONCLUSIONS: Bacterial etiology of necrotizing pneumonia in children varied with the presence or absence of a complex chronic condition. Bacterial isolation is associated with increased invasive procedures and complications. The mortality rate is higher in children with complex chronic conditions. This study provides national data on necrotizing pneumonia among hospitalized children. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Pediatric Chronic Critical Illness: Validation, Prevalence, and Impact in a Children’s Hospital
CONCLUSIONS: Pediatric chronic critical illness patients occupied more than one third of the ICU beds and have five times longer stay. This mounting load needs to be uniformly defined, addressed at regional and national levels, and considered in the current pandemic planning. (Source: Pediatric Critical Care Medicine)
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Brief Reports Source Type: research

Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery: A Retrospective Multicenter Study
OBJECTIVES: We aimed to describe characteristics and operative outcomes from a multicenter cohort of infants who underwent repair of anomalous left coronary artery from the pulmonary artery. We also aimed to identify factors associated with major adverse cardiovascular events following anomalous left coronary artery from the pulmonary artery repair. DESIGN: Retrospective chart review. SETTING: Twenty-one tertiary-care referral centers. PATIENTS: Infants less than 365 days old who underwent anomalous left coronary artery from the pulmonary artery repair. INTERVENTIONS: None. MEASUREMENTS A...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Cardiac Intensive Care Source Type: research

Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study
OBJECTIVES: To characterize the pediatric super-refractory status epilepticus population by describing treatment variability in super-refractory status epilepticus patients and comparing relevant clinical characteristics, including outcomes, between super-refractory status epilepticus, and nonsuper-refractory status epilepticus patients. DESIGN: Retrospective cohort study with prospectively collected data between June 2011 and January 2019. SETTING: Seventeen academic hospitals in the United States. PATIENTS: We included patients 1 month to 21 years old presenting with convulsive refractory status ...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Continuous Renal-Replacement Therapy in Critically Ill Children: Practice Changes and Association With Outcome
This study was designed to evaluate practice changes and outcomes over a 10-year period in a large single-center PICU cohort that received continuous renal-replacement therapy. DESIGN: Retrospective study design. SETTING: A multidisciplinary tertiary PICU of a university-affiliated hospital in Guangzhou, China. PATIENTS: All critically ill children who were admitted to our PICU from January 2010 to December 2019 and received continuous renal-replacement therapy were included in this study. MEASUREMENTS AND MAIN RESULTS: A total of 289 patients were included in the study. Of the two study periods...
Source: Pediatric Critical Care Medicine - December 1, 2021 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research