A randomized, double-blind, dose-controlled study of the use of dexmedetomidine alone for procedural sedation of children and adolescents undergoing MRI scans
CONCLUSIONS: Dexmedetomidine was well tolerated. The high dose was associated with meaningfully greater efficacy compared with lower doses. Based on these results, the recommended starting dose for procedural sedation in children ≥1month-<2years is loading dose 1.5 mcg/kg/maintenance infusion 1.5 mcg/kg/h; children ≥2-<17years is loading dose 2.0 mcg/kg/maintenance infusion 1.5 mcg/kg/h.PMID:38363011 | DOI:10.1111/pan.14857 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 16, 2024 Category: Anesthesiology Authors: Umar Khan Gregory B Hammer Cassandra Duncan-Azadi Yasuyuki Suzuki Deborah Chiles Sunring Chime Phillip Chappell Source Type: research
A randomized, double-blind, dose-controlled study of the use of dexmedetomidine alone for procedural sedation of children and adolescents undergoing MRI scans
CONCLUSIONS: Dexmedetomidine was well tolerated. The high dose was associated with meaningfully greater efficacy compared with lower doses. Based on these results, the recommended starting dose for procedural sedation in children ≥1month-<2years is loading dose 1.5 mcg/kg/maintenance infusion 1.5 mcg/kg/h; children ≥2-<17years is loading dose 2.0 mcg/kg/maintenance infusion 1.5 mcg/kg/h.PMID:38363011 | DOI:10.1111/pan.14857 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 16, 2024 Category: Anesthesiology Authors: Umar Khan Gregory B Hammer Cassandra Duncan-Azadi Yasuyuki Suzuki Deborah Chiles Sunring Chime Phillip Chappell Source Type: research
The state of point-of-care ultrasound training in pediatric anesthesia fellowship programs in the United States: A survey assessment
CONCLUSIONS: This observational survey-based study suggests that fewer than half of pediatric anesthesia training programs in the United States offer point-of-care ultrasound education. Additional research is needed to optimize this education and training in pediatric anesthesia fellowship programs.PMID:38358309 | DOI:10.1111/pan.14851 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 15, 2024 Category: Anesthesiology Authors: Elizabeth M O'Brien Rodrigo Daly Guris William Quarshie Elaina E Lin Source Type: research
Impact of dietary ketosis on volatile anesthesia toxicity in a model of Leigh syndrome
CONCLUSIONS: Our findings suggest that extra caution should be taken in the anesthetic management of mitochondrial disease patients in dietary ketosis.PMID:38358320 | DOI:10.1111/pan.14855 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 15, 2024 Category: Anesthesiology Authors: Kira A Spencer Miranda N Howe Michael T Mulholland Vivian Truong Ryan W Liao Yihan Chen Monyreak Setha John C Snell Allison Hanaford Katerina James Philip G Morgan Margaret M Sedensky Simon C Johnson Source Type: research
Negative pressure suction test
Paediatr Anaesth. 2024 Feb 15. doi: 10.1111/pan.14859. Online ahead of print.NO ABSTRACTPMID:38358324 | DOI:10.1111/pan.14859 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 15, 2024 Category: Anesthesiology Authors: Rodrigo J Daly Guris Alison R Perate Source Type: research
Goal-directed fluid therapy guided by plethysmographic variability index versus conventional liberal fluid therapy in neonates undergoing abdominal surgery: A prospective randomized controlled trial
CONCLUSION: Intraoperative plethysmographic variability index-guided goal-directed fluid therapy was comparable to liberal fluid therapy in terms of total volume of fluid infused in neonates during perioperative period. More randomized controlled trials with higher sample size are required.TRIAL REGISTRATION: Central Trial Registry of India (CTRI/2020/02/023561).PMID:38348932 | DOI:10.1111/pan.14856 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 13, 2024 Category: Anesthesiology Authors: A S Swathy Anudeep Jafra Neerja Bhardwaj Ravi P Kanojia Monika Bawa Source Type: research
Global pediatric anesthesia-Anglophone West Africa perspective
This article gives the pediatric anesthesia perspective from Cameroon, Nigeria, Ghana, Liberia, and Gambia, five out of six countries in Anglophone West Africa. Over 40% of the population of most of these countries are younger than 14 years and there is an increasing need for paediatric anesthesia services.FINDINGS: Workforce density ranges from 0.08 to 0.58 physician anesthesia providers per 100,000 population. There are only 13 trained pediatric anesthetists; ratios range from 0 to 0.4 per 100,000 children, thus pediatric anesthesia services are provided by various cadres of physician and non-physician anesthesia provide...
Source: Paediatric Anaesthesia - February 7, 2024 Category: Anesthesiology Authors: Ibironke Desalu Pokua Sarpong Maryrose O Osazuwa Raymond Ndikontar Kwinji Aramide Folayemi Faponle Musa Kallamu Suleiman Junette Metogo Mbengono Epse Njoki Iniabasi Ilori Olayinka R Eyelade Anastasia Abena Ohene Audrey Anno William Addison Source Type: research
Comparison of gastric emptying time between breast-fed and formula milk-fed infants less than 6 months old, using gastric ultrasound-An observational study
CONCLUSION: In our series, the gastric emptying times in breast-fed and formula-fed infants less than 6 months old were similar. Our results support the fasting guidelines of the European Society of Anaesthesiology and Intensive Care 2022, that is, 3 h for breastfeeding and 4 h for formula milk feeding. In addition, this shows that the Schmitz's and Spencer's formulae used to calculate the gastric volume based on ultrasound measurement of the antral cross-sectional area are not comparable in infants less than 6 months.PMID:38323713 | DOI:10.1111/pan.14841 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 7, 2024 Category: Anesthesiology Authors: Debashis Das Anjan Trikha Manpreet Kaur Thilaka Muthiah Ravinder Kumar Pandey Basavraj Ankalji Kumble Seetharama Madhusudhan Deep Narayan Srivastava Preet Mohinder Singh Source Type: research
Changes in branched-chain amino acids in an infant with maple syrup urine disease during perioperative pediatric liver transplant: A case report
Paediatr Anaesth. 2024 Feb 5. doi: 10.1111/pan.14842. Online ahead of print.ABSTRACTAn 11-month-old female infant diagnosed with classic subtype IB maple syrup urine disease underwent living donor liver transplantation. Blood samples for plasma amino acid analysis were collected during the three phases of the operation. Despite the perioperative prophylactic administration of 12.5% hypertonic dextrose solution with insulin and a 20% intralipid emulsion, the blood levels of the branched-chain amino acids increased dramatically during surgery, consistent with an acute intraoperative metabolic decompensation. However, these b...
Source: Paediatric Anaesthesia - February 5, 2024 Category: Anesthesiology Authors: Pipat Saeyup Chomchanat Tubjaroen Wuttichart Kamolvisit Voranush Chongsrisawat Winnie Thaveepunsan Source Type: research
The effect of augmented reality on preoperative anxiety in children and adolescents: A randomized controlled trial. Comments on Chamberland et al
Paediatr Anaesth. 2024 Feb 2. doi: 10.1111/pan.14853. Online ahead of print.NO ABSTRACTPMID:38303681 | DOI:10.1111/pan.14853 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 2, 2024 Category: Anesthesiology Authors: Kristina Ooi Jonathan Weale Source Type: research
Randomized controlled trial to evaluate the rate of successful neonatal endotracheal intubation performed with a stylet versus without a stylet
CONCLUSION: Endotracheal intubation using a stylet did not significantly improve the success rate of the procedure, however, intubation time significantly varied between groups and in different conditions. The rigidity and curvature provided by the stylet may facilitate the process of intubation when smaller caliber endotracheal tubes are used.PMID:38305632 | DOI:10.1111/pan.14845 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 2, 2024 Category: Anesthesiology Authors: Shailesh Solanki Shivani Dogra Pramod K Gupta Nitin J Peters Muneer A Malik J K Mahajan Source Type: research
A systematic review of neurological airway respiratory cardiovascular other-surgical severity (NARCO-SS) score as a pediatric perioperative scoring system
CONCLUSIONS: This review has identified a need for high-quality studies assessing NARCO-SS before recommendations for clinical practice can be made. Addressing its limitations and enhancing the NARCO-SS through targeted refinements of its individual descriptive categories could potentially lead to improvement in its overall predictive accuracy and facilitate wider adoption into clinical practice.PMID:38300020 | DOI:10.1111/pan.14846 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - February 1, 2024 Category: Anesthesiology Authors: Ashwin N Udupa Ahan A Majmudar Liem Tran Source Type: research
Perioperative methadone for posterior spinal fusion in adolescents: Results from a double-blind randomized-controlled trial
CONCLUSIONS: A two-dose intraoperative methadone regimen resulted in decreased opioid consumption compared to morphine. Although the clinical significance of these results may be limited, the analgesic equipoise without increased opioid-related side effects and potential for a lower incidence of chronic pain may tip the balance in favor of routine methadone use for adolescents undergoing posterior spinal fusion.PMID:38288667 | DOI:10.1111/pan.14843 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - January 30, 2024 Category: Anesthesiology Authors: Roger A Fons Keri R Hainsworth Johanna Michlig Megan Jablonski Michelle L Czarnecki Steven J Weisman Source Type: research
Dexmedetomidine and magnesium sulfate in preventing junctional ectopic tachycardia after pediatric cardiac surgery
CONCLUSION: Dexmedetomidine alone or combined with MgSO4 had a therapeutic role in the prevention of JET in children after congenital heart surgery.PMID:38269418 | DOI:10.1111/pan.14848 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - January 25, 2024 Category: Anesthesiology Authors: Passaint Fahim Hassan Ahmed M El Haddad Source Type: research
In this issue March 2024
Paediatr Anaesth. 2024 Mar;34(3):191-192. doi: 10.1111/pan.14849. Epub 2024 Jan 25.NO ABSTRACTPMID:38269447 | DOI:10.1111/pan.14849 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - January 25, 2024 Category: Anesthesiology Source Type: research
