Neurosurgery Clinics of North America This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Perioperative Management of Patients with Glioblastoma
This article presents the perioperative management of patients with glioblastoma including tools and surgical adjuncts to maximize extent of resection and minimize poor outcomes. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - November 4, 2020 Category: Neurosurgery Authors: Gaetano De Biase, Diogo P. Garcia, Angela Bohnen, Alfredo Qui ñones-Hinojosa Source Type: research

Extent of Resection of Glioblastoma
The work of modern neurosurgical glioma practice combines securing accurate diagnoses, under the 2016 revised World Health Organization (WHO) Classification of Tumors of the Central Nervous System, with an aggressive and safe surgical pursuit of tumor removal. The evidence base that drives clinical decision-making has undergone a critical reevaluation with the incorporation of molecular classifiers into the updated WHO diagnoses including the 3 most common diffuse gliomas in adults: glioblastoma IDH wild-type, astrocytoma IDH mutant, and oligodendroglioma IDH mutant 1p/19q codeleted. The studies that form the foundation of...
Source: Neurosurgery Clinics of North America - November 4, 2020 Category: Neurosurgery Authors: Daniel P. Cahill Source Type: research

Surgical Management of Glioblastoma: More Than Just Diagnosis and Decompression
Despite recent advances in our understanding of the biology of glioblastoma (GBM) and the completion of multiple, multiple clinical trials aimed at using this knowledge to evaluate the effectiveness of novel targeted therapies, immunotherapies, gene therapies, and locoregional therapies, GBM remains an unrelentingly fatal form of cancer. There is an understandable sense of nihilism and fatalism that drives the approach of many clinicians to consider GBM (and gliomas in general) to fall into the realm of general neurosurgical practice, with the goals of surgery limited to diagnosis and decompression followed by transfer of ...
Source: Neurosurgery Clinics of North America - November 4, 2020 Category: Neurosurgery Authors: Michael A. Vogelbaum Tags: Preface Source Type: research

Initial Approach to Patients with a Newly Diagnosed Solitary Brain Metastasis
Solitary brain metastasis is defined by a single metastatic brain lesion as the only site of metastasis. The initial approach to this condition consists of radiographical evaluation to establish diagnosis, followed by assessment of functional and prognostic status. Neurologic symptom management consists of using dexamethasone and antiepileptic medications. Treatment consists of a combination of surgical and radiation therapy. Surgical treatment is indicated where there is a need for tissue diagnosis or immediate alleviation of neurologic symptoms and mass effect. Stereotactic radiosurgery has become an effective treatment ...
Source: Neurosurgery Clinics of North America - September 11, 2020 Category: Neurosurgery Authors: James K.C. Liu Source Type: research

Initial Approach to the Patient with Multiple Newly Diagnosed Brain Metastases
Brain metastases are the most common intracranial tumor in adults, with increasing incidence owing to prolonged survival times. Roughly half of patients diagnosed with new brain metastases have greater than 1 brain metastasis at the time of diagnosis, raising the question of how to optimize patient care with multiple brain metastases. The authors review studies relevant to the care of patients with brain metastasis, with emphasis on those relevant to the care of patients with multiple brain metastases. They discuss evolving strategies involving multiple modalities and the benefit of surgical management in patients with a l...
Source: Neurosurgery Clinics of North America - September 11, 2020 Category: Neurosurgery Authors: Clara Kwon Starkweather, Bryan D. Choi, Christopher Alvarez-Breckenridge, Priscilla K. Brastianos, Kevin Oh, Nancy Wang, Helen Shih, Brian V. Nahed Source Type: research