Forthcoming Issues
Disorders and Treatment of the Cerebral Venous System (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - February 28, 2024 Category: Neurosurgery Source Type: research

Transformative Spine Surgery: A Paradigm Shift in Treatment and Technology
The field of spinal surgery has experienced a surge of transformative advancements, departing from traditional reliance on harvested autografts, stainless steel implants, and continuous fluoroscopy. This issue deals with the latest advances and the future of the field of spinal surgery. The last three decades have been a remarkable journey, showcasing a leap in surgical techniques and approaches that have forever transformed the care of our patients with degenerative, traumatic, neoplastic, and infectious processes. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - January 23, 2024 Category: Neurosurgery Authors: Adam S. Kanter, Nicholas Theodore Tags: Preface Source Type: research

Image-Guided Spine Surgery
This article explores the evolution, classification, and impact of image-guided spine surgery, underscoring its pivotal role in enhancing efficacy and safety while setting the stage for the incorporation of future technological advancements. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - January 3, 2024 Category: Neurosurgery Authors: Khanathip Jitpakdee, Blake Boadi, Roger H ärtl Source Type: research

Advances in Imaging (Intraop Cone-Beam Computed Tomography, Synthetic Computed Tomography, Bone Scan, Low-Dose Protocols)
Spine surgery has seen a rapid advance in the refinement and development of 3-dimensional and nuclear imaging modalities in recent years. Cone-beam CT has proven to be a valuable tool for improving the accuracy of pedicle screw placement. The use of synthetic CT and low-dose CT have also emerged as modalities which allow for little to no radiation while streamlining imaging workflows. Bone scans also serve to provide functional information about bone metabolism in both the preoperative and postoperative monitoring phases. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - December 29, 2023 Category: Neurosurgery Authors: Pawel P. Jankowski, Justin P. Chan Source Type: research

Augmented Reality and Virtual Reality in Spine Surgery
Augmented reality (AR) and virtual reality (VR) are powerful technologies with proven utility and tremendous potential. Spine surgery, in particular, may benefit from these developing technologies for resident training, preoperative education for patients, surgical planning and execution, and patient rehabilitation. In this review, the history, current applications, challenges, and future of AR/VR in spine surgery are examined. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - December 22, 2023 Category: Neurosurgery Authors: Brendan F. Judy, Arjun Menta, Ho Lim Pak, Tej D. Azad, Timothy F. Witham Source Type: research

Functional Stimulation and Imaging to Predict Neuromodulation of Chronic Low Back Pain
Back pain is one of the most common aversive sensations in human experience. Pain is not limited to the sensory transduction of tissue damage; rather, it encompasses a range of nervous system activities including lateral modulation, long-distance transmission, encoding, and decoding. Although spine surgery may address peripheral pain generators directly, aberrant signals along canonical aversive pathways and maladaptive influence of affective and cognitive states can result in persistent subjective pain refractory to classical surgical intervention. The clinical identification of who will benefit from surgery —and who wi...
Source: Neurosurgery Clinics of North America - December 21, 2023 Category: Neurosurgery Authors: Timothy J. Florence, Ausaf Bari, Andrew C. Vivas Source Type: research

Digital Phenotyping, Wearables, and Outcomes
There is a significant need for robust and objective outcome assessments in spine surgery. Constant monitoring via smartphones and wearable devices has the potential to fill this role by providing an in-depth picture of human well-being, creating an unprecedented amount of objective data to augment clinical decision-making. The metrics obtained from continuous patient monitoring increase the amount and ecological validity of data relevant to spine surgery. This can provide physicians with patient and disease-specific medical information, facilitating personalized patient care. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - December 21, 2023 Category: Neurosurgery Authors: Anshul Ratnaparkhi, Joel Beckett Source Type: research

Advances in Anterolateral Approaches to the Lumbar Spine
A historical overview of the evolution of anterolateral approaches to the lumber spine and associated patient outcomes is presented. In addition, the modern incorporation of new technologies is discussed, including interbody cages, intraoperative image guidance, robotics, augmented reality, and machine learning, which have significantly improved the spine surgery safety and efficacy profile. Current challenges and future directions are also covered, emphasizing the need for further research and development, particularly in robotic assistance and machine learning algorithms. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - December 18, 2023 Category: Neurosurgery Authors: Rohit Prem Kumar, Galal A. Elsayed, Daniel M. Hafez, Nitin Agarwal Source Type: research

Smart Spine Implants
This article discusses advances in smart spinal implant technology and how they may aid patients and surgeons. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - December 15, 2023 Category: Neurosurgery Authors: Rory K.J. Murphy Source Type: research

Advancements in Robotic-Assisted Spine Surgery
Applications and workflows around spinal robotics have evolved since these systems were first introduced in 2004. Initially approved for lumbar pedicle screw placement, the scope of robotics has expanded to instrumentation across different regions. Additionally, precise navigation can aid in tumor resection or spinal lesion ablation. Robot-assisted surgery can improve accuracy while decreasing radiation exposure, length of hospital stay, complication, and revision rates. Disadvantages include increased operative time, dependence on preoperative imaging among others. The future of robotic spine surgery includes automated su...
Source: Neurosurgery Clinics of North America - December 6, 2023 Category: Neurosurgery Authors: A. Daniel Davidar, Kelly Jiang, Carly Weber-Levine, Meghana Bhimreddy, Nicholas Theodore Source Type: research

Artificial Intelligence in Spine Surgery
The amount and quality of data being used in our everyday lives continue to advance in an unprecedented pace. This digital revolution has permeated healthcare, specifically spine surgery, allowing for very advanced and complex computational analytics, such as artificial intelligence (AI) and machine learning (ML). The integration of these methods into clinical practice has just begun, and the following review article will describe AI/ML, demonstrate how it has been applied in adult spinal deformity surgery, and show its potential to improve patient care touching on future directions. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - November 29, 2023 Category: Neurosurgery Authors: Justin K. Scheer, Christopher P. Ames Source Type: research

Advances in Implant Technologies for Spine Surgery
Spine implants are becoming increasingly diversified. Taking inspiration from other industries, three-dimensional modeling of the spinal column has helped meet the custom needs of individual patients as both en bloc replacements and pedicle screw designs. Intraoperative tailoring of devices, a common need in the operating room, has led to expandable versions of cages and interbody spacers. (Source: Neurosurgery Clinics of North America)
Source: Neurosurgery Clinics of North America - November 24, 2023 Category: Neurosurgery Authors: Shahab Aldin Sattari, Yuanxuan Xia, Tej D. Azad, Chad A. Caraway, Louis Chang Source Type: research

Acute Effect of Vagus Nerve Stimulation in Patients with Drug-Resistant Epilepsy
This study presents a preliminary exploration of the acute effect of VNS. SEEG signals were collected to assess the acute effect of VNS on neural synchronization in patients with drug-resistant epilepsy, especially in epileptogenic networks. The results show that the better the efficacy of VNS, the wider the spread of desynchronization assessed by weighted phase lag index at a high frequency band caused by VNS. Future studies should focus on the association between the change in synchronization and the efficacy of VNS, exploring the possibility of synchronization as a biomarker for patient screening and parameter programmi...
Source: Neurosurgery Clinics of North America - November 23, 2023 Category: Neurosurgery Authors: Xiaoya Qin, Yuan Yuan, Huiling Yu, Yi Yao, Luming Li Source Type: research

Pediatric Neurostimulation and Practice Evolution
Since the late nineteenth century, the prevailing view of epilepsy surgery has been to identify a seizure focus in a medically refractory patient and eradicate it. Sadly, only a select number of the many who suffer from uncontrolled seizures benefit from this approach. With the development of safe, efficient stereotactic methods and targeted surgical therapies that can affect deep structures and modulate broad networks in diverse disorders, epilepsy surgery in children has undergone a paradigmatic evolutionary change. With modern diagnostic techniques such as stereo electroencephalography combined with closed loop neuromod...
Source: Neurosurgery Clinics of North America - November 23, 2023 Category: Neurosurgery Authors: Saadi Ghatan Source Type: research

Evolution of Stereo-Electroencephalography at Massachusetts General Hospital
The practice of invasive monitoring for presurgical epilepsy workup has evolved at Massachusetts General Hospital (MGH) in parallel to the evolution in the field ’s understanding of epilepsy as a network disorder. Implantations have shifted from an emphasis on singularly finding single foci for the purpose of resection to a network-hypothesis–driven approach aiming to delineate patients’ seizure networks with the goal of developing surgical interventio ns that disrupt critical nodes of these networks. Here, the authors review all invasive monitoring cases at MGH from April 2016 through June 2023 to describe how this ...
Source: Neurosurgery Clinics of North America - November 23, 2023 Category: Neurosurgery Authors: Pranav Nanda, R. Mark Richardson Source Type: research