Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Analysis of triacylglycerol and phospholipid sn-positional isomers by liquid chromatographic and mass spectrometric methodologies
Mass Spectrom Rev. 2023 Jun 6. doi: 10.1002/mas.21853. Online ahead of print.ABSTRACTAnalysis of triacylglycerol (TG) and phospholipid sn-positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods. Due to long retention times and limited performance, researchers are moving away from direct chromatographic separation of isomers, using mass spectrometry instead. Many established analytical methods are targeting spe...
Source: Mass Spectrometry Reviews - June 6, 2023 Category: Molecular Biology Authors: Mikael Fabritius Baoru Yang Source Type: research
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Mass Spectrom Rev. 2023 Jun 1. doi: 10.1002/mas.21851. Online ahead of print.ABSTRACTRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM-MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM-MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas-phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent...
Source: Mass Spectrometry Reviews - June 1, 2023 Category: Molecular Biology Authors: Magdalena M Zimnicka Source Type: research
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Mass Spectrom Rev. 2023 Jun 1. doi: 10.1002/mas.21851. Online ahead of print.ABSTRACTRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM-MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM-MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas-phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent...
Source: Mass Spectrometry Reviews - June 1, 2023 Category: Molecular Biology Authors: Magdalena M Zimnicka Source Type: research
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Mass Spectrom Rev. 2023 Jun 1. doi: 10.1002/mas.21851. Online ahead of print.ABSTRACTRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM-MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM-MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas-phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent...
Source: Mass Spectrometry Reviews - June 1, 2023 Category: Molecular Biology Authors: Magdalena M Zimnicka Source Type: research
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Mass Spectrom Rev. 2023 Jun 1. doi: 10.1002/mas.21851. Online ahead of print.ABSTRACTRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM-MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM-MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas-phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent...
Source: Mass Spectrometry Reviews - June 1, 2023 Category: Molecular Biology Authors: Magdalena M Zimnicka Source Type: research
Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry
Mass Spectrom Rev. 2023 Jun 1. doi: 10.1002/mas.21851. Online ahead of print.ABSTRACTRecent advances in instrumentation and development of computational strategies for ion mobility mass spectrometry (IM-MS) studies have contributed to an extensive growth in the application of this analytical technique to comprehensive structural description of supramolecular systems. Apart from the benefits of IM-MS for interrogation of intrinsic properties of noncovalent aggregates in the experimental gas-phase environment, its merits for the description of native structural aspects, under the premises of having maintained the noncovalent...
Source: Mass Spectrometry Reviews - June 1, 2023 Category: Molecular Biology Authors: Magdalena M Zimnicka Source Type: research
Quantification of snake venom proteomes by mass spectrometry-considerations and perspectives
Mass Spectrom Rev. 2023 May 8. doi: 10.1002/mas.21850. Online ahead of print.ABSTRACTThe advent of soft ionization mass spectrometry-based proteomics in the 1990s led to the development of a new dimension in biology that conceptually allows for the integral analysis of whole proteomes. This transition from a reductionist to a global-integrative approach is conditioned to the capability of proteomic platforms to generate and analyze complete qualitative and quantitative proteomics data. Paradoxically, the underlying analytical technique, molecular mass spectrometry, is inherently nonquantitative. The turn of the century wit...
Source: Mass Spectrometry Reviews - May 8, 2023 Category: Molecular Biology Authors: Juan J Calvete Bruno Lomonte Anthony J Saviola Francisco Calder ón Celis Jorge Ruiz Encinar Source Type: research
Quantification of snake venom proteomes by mass spectrometry-considerations and perspectives
Mass Spectrom Rev. 2023 May 8. doi: 10.1002/mas.21850. Online ahead of print.ABSTRACTThe advent of soft ionization mass spectrometry-based proteomics in the 1990s led to the development of a new dimension in biology that conceptually allows for the integral analysis of whole proteomes. This transition from a reductionist to a global-integrative approach is conditioned to the capability of proteomic platforms to generate and analyze complete qualitative and quantitative proteomics data. Paradoxically, the underlying analytical technique, molecular mass spectrometry, is inherently nonquantitative. The turn of the century wit...
Source: Mass Spectrometry Reviews - May 8, 2023 Category: Molecular Biology Authors: Juan J Calvete Bruno Lomonte Anthony J Saviola Francisco Calder ón Celis Jorge Ruiz Encinar Source Type: research
