A tutorial: Laserspray ionization and related laser-based ionization methods for use in mass spectrometry
Mass Spectrom Rev. 2023 Jul 18:e21762. doi: 10.1002/mas.21762. Online ahead of print.ABSTRACTThis Tutorial is to provide a summary of parameters useful for successful outcomes of laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix:analyte sample to produce highly charged ions. In these methods the purpose of the laser is to transfer matrix-analyte clusters into the gas phase. Ions are hypothesized to be produced by a thermal process where emitted matrix:analyte gas-phase particles/clusters are charged and loss of matrix from the charged particles leads to release of the analyte ions into ...
Source: Mass Spectrometry Reviews - July 18, 2023 Category: Molecular Biology Authors: Sarah Trimpin Source Type: research
A tutorial: Laserspray ionization and related laser-based ionization methods for use in mass spectrometry
Mass Spectrom Rev. 2023 Jul 18:e21762. doi: 10.1002/mas.21762. Online ahead of print.ABSTRACTThis Tutorial is to provide a summary of parameters useful for successful outcomes of laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix:analyte sample to produce highly charged ions. In these methods the purpose of the laser is to transfer matrix-analyte clusters into the gas phase. Ions are hypothesized to be produced by a thermal process where emitted matrix:analyte gas-phase particles/clusters are charged and loss of matrix from the charged particles leads to release of the analyte ions into ...
Source: Mass Spectrometry Reviews - July 18, 2023 Category: Molecular Biology Authors: Sarah Trimpin Source Type: research
A tutorial: Laserspray ionization and related laser-based ionization methods for use in mass spectrometry
Mass Spectrom Rev. 2023 Jul 18:e21762. doi: 10.1002/mas.21762. Online ahead of print.ABSTRACTThis Tutorial is to provide a summary of parameters useful for successful outcomes of laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix:analyte sample to produce highly charged ions. In these methods the purpose of the laser is to transfer matrix-analyte clusters into the gas phase. Ions are hypothesized to be produced by a thermal process where emitted matrix:analyte gas-phase particles/clusters are charged and loss of matrix from the charged particles leads to release of the analyte ions into ...
Source: Mass Spectrometry Reviews - July 18, 2023 Category: Molecular Biology Authors: Sarah Trimpin Source Type: research
Editorial: Frank Turecek Laudation
Mass Spectrom Rev. 2023 Jul 14. doi: 10.1002/mas.21859. Online ahead of print.NO ABSTRACTPMID:37449682 | DOI:10.1002/mas.21859 (Source: Mass Spectrometry Reviews)
Source: Mass Spectrometry Reviews - July 14, 2023 Category: Molecular Biology Authors: Karel Lemr Vladim ír Havlíček Source Type: research
Editorial: Frank Turecek Laudation
Mass Spectrom Rev. 2023 Jul 14. doi: 10.1002/mas.21859. Online ahead of print.NO ABSTRACTPMID:37449682 | DOI:10.1002/mas.21859 (Source: Mass Spectrometry Reviews)
Source: Mass Spectrometry Reviews - July 14, 2023 Category: Molecular Biology Authors: Karel Lemr Vladim ír Havlíček Source Type: research
Editorial: Frank Turecek Laudation
Mass Spectrom Rev. 2023 Jul 14. doi: 10.1002/mas.21859. Online ahead of print.NO ABSTRACTPMID:37449682 | DOI:10.1002/mas.21859 (Source: Mass Spectrometry Reviews)
Source: Mass Spectrometry Reviews - July 14, 2023 Category: Molecular Biology Authors: Karel Lemr Vladim ír Havlíček Source Type: research
Editorial: Frank Turecek Laudation
Mass Spectrom Rev. 2023 Jul 14. doi: 10.1002/mas.21859. Online ahead of print.NO ABSTRACTPMID:37449682 | DOI:10.1002/mas.21859 (Source: Mass Spectrometry Reviews)
Source: Mass Spectrometry Reviews - July 14, 2023 Category: Molecular Biology Authors: Karel Lemr Vladim ír Havlíček Source Type: research
Recent advances in mass spectrometry techniques for atmospheric chemistry research on molecular-level
Mass Spectrom Rev. 2023 Jul 13. doi: 10.1002/mas.21857. Online ahead of print.ABSTRACTThe Earth's atmosphere is composed of an enormous variety of chemical species associated with trace gases and aerosol particles whose composition and chemistry have critical impacts on the Earth's climate, air quality, and human health. Mass spectrometry analysis as a powerful and popular analytical technique has been widely developed and applied in atmospheric chemistry for decades. Mass spectrometry allows for effective detection, identification, and quantification of a broad range of organic and inorganic chemical species with high sen...
Source: Mass Spectrometry Reviews - July 13, 2023 Category: Molecular Biology Authors: Wen Zhang Lu Xu Haofei Zhang Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
Characterization of mRNA therapeutics
Mass Spectrom Rev. 2023 Jul 4. doi: 10.1002/mas.21856. Online ahead of print.ABSTRACTTherapeutic messenger RNAs (mRNAs) have emerged as powerful tools in the treatment of complex diseases, especially for conditions that lack efficacious treatment. The successful application of this modality can be attributed to its ability to encode entire proteins. While the large nature of these molecules has supported their success as therapeutics, its extended size creates several analytical challenges. To further support therapeutic mRNA development and its deployment in clinical trials, appropriate methods to support their characteri...
Source: Mass Spectrometry Reviews - July 4, 2023 Category: Molecular Biology Authors: Guilherme J Guimaraes Jaeah Kim Michael G Bartlett Source Type: research
