Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?
Mass Spectrom Rev. 2024 Apr 5. doi: 10.1002/mas.21880. Online ahead of print.ABSTRACTAffinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a purified potential partner, in model systems such as model membranes, and with live cells using both targeted and nontargeted proteomics studies. Different biological partners will be described, amon...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Astrid Walrant Emmanuelle Sachon Source Type: research
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrom Rev. 2024 Apr 4. doi: 10.1002/mas.21882. Online ahead of print.ABSTRACTLung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer. Differences in glycosylation patterns have been previously observed between healthy and cancerous samples as well as between different lung cancer subtypes, which suggests untapped diagnostic potential. In addition, understanding the changes mediated by glycosylation may shed light on possible novel...
Source: Mass Spectrometry Reviews - April 5, 2024 Category: Molecular Biology Authors: Mirjam Balbisi Simon Sug ár Lilla Turi ák Source Type: research
