Effects of photodynamic laser and violet-blue led irradiation on Staphylococcus aureus biofilm and Escherichia coli lipopolysaccharide attached to moderately rough titanium surface: in vitro study
This study investigates the in vitro efficacy of photodynamic treatment (PDT) with methylene blue (MB) photoactivated with λ 635 nm diode laser and of λ 405 nm violet-blue LED phototreatment for the reduction of bacterial biofilm and lipopolysaccharide (LPS) adherent to titanium surface mimicking the bone-implant interface.Staphylococcus aureus biofilm grown on titanium discs with a moderately rough surface was subjected to either PDT (0.1% MB and λ 635 nm diode laser) or λ 405 nm LED phototreatment for 1 and 5 min. Bactericidal effect was evaluated by vital staining and...
Source: Lasers in Medical Science - March 10, 2017 Category: Laser Surgery Source Type: research

Virulence factors of fluconazole-susceptible and fluconazole-resistant Candida albicans after antimicrobial photodynamic therapy
This study evaluated the effects of antimicrobial photodynamic therapy (aPDT) mediated by Photodithazine ® (PDZ) and LED light on the virulence factors of fluconazole-susceptible (CaS) and fluconazole-resistant (CaR)Candida albicans. Standardized suspensions of strains were prepared (107), and after 48  h of biofilm formation, these strains were incubated with PDZ (100 mg/L) for 20 min and exposed to LED light (660 nm, 37.5 J/cm2). Additional samples were treated with PDZ or light only, and the control consisted of biofilms that received no treatment. After aPDT, the cells were recovered and th...
Source: Lasers in Medical Science - March 9, 2017 Category: Laser Surgery Source Type: research

Histomorphologic and ultrastructural recovery of myopathy in rats treated with low-level laser therapy
AbstractThe purpose of the present work was to study the effect of low-level laser therapy (LLLT): helium-neon (He-Ne) and gallium arsenide (Ga-As) laser on the histomorphology of muscle and mitochondria in experimental myopathy in rats. Thirty Suqu ía strain female rats were distributed in groups: (A) control (intact), (B) injured, (C) injured and treated with He-Ne laser, (D) injured and treated with Ga-As laser, (E) irradiated with He-Ne laser on the non-injured muscle, and (F) irradiated with Ga-As laser on the non-injured muscle. Myopathy was induced by injecting 0.05 mg/rat/day of adrenaline in the left g...
Source: Lasers in Medical Science - March 9, 2017 Category: Laser Surgery Source Type: research

Shear bond, wettability and AFM evaluations on CO 2 laser-irradiated CAD/CAM ceramic surfaces
AbstractThe purpose of this study is to determine the CO2 laser irradiation in comparison with sandblasting (Sb), hydrofluoric acid (Hf) and silane coupling agent (Si) on shear bond strength (SBS), roughness (Rg) and wettability (Wt) of resin cement to CAD/CAM ceramics. Sixty (CAD/CAM) ceramic discs were prepared and distributed into six different groups: group A, control lithium disilicate (Li); group B, control zirconia (Zr); group C, Li: CO2/HF/Si; group D, Li: HF/Si; group E, Zr: CO2/Sb/Si; group F, Zr: Sb/Si. Result showed significant difference between irradiated and non-irradiated in terms of shear bond strength for...
Source: Lasers in Medical Science - March 9, 2017 Category: Laser Surgery Source Type: research

Depigmentation with Q-switched Nd:YAG laser in universal vitiligo: a long-term follow-up study of 4  years
This study was conducted to assess the safety and long-term follow-up results of QS Nd:YAG laser treatment in combination with need-based topical depigmentation therapy for universal vitiligo. A retrospective study was performed on patients with universal vitiligo who had received QS Nd:YAG laser treatment from 2010 to 2013. All patients were contacted and called for follow-up. Patients who reported were assessed clinically and information regarding adverse effects and relapse (repigmentation) in the follow-up period were obtained. Any need for topical depigmenting creams or other interventions and overall satisfaction to ...
Source: Lasers in Medical Science - March 7, 2017 Category: Laser Surgery Source Type: research

Quantifying glucose and lipid components in human serum by Raman spectroscopy and multivariate statistics
This study aimed to develop a spectral model to estimate the concentration of glucose and lipid fractions in human serum, thus evaluating the feasibility of Raman spectroscopy technique for diagnostic purposes. A total of 44 samples of blood serum were collected from volunteers submitted to routine blood biochemical assay analysis. The biochemical concentrations of glucose, triglycerides, cholesterol, and high-density and low-density lipoproteins (HDL and LDL) were obtained by colorimetric method. Serum samples (200  μL) were submitted to Raman spectroscopy (830 nm, 250 mW, 50-s accumulation). The spectra...
Source: Lasers in Medical Science - March 7, 2017 Category: Laser Surgery Source Type: research

LLLT actives MMP-2 and increases muscle mechanical resistance after nerve sciatic rat regeneration
AbstractThe purpose of this study was to analyze the low-level laser therapy (LLLT) on metalloproteinase expression and the mechanical strength of skeletal muscle regeneration after peripheral nerve injury. Rats were subjected to crush injury of the right sciatic nerve, followed by LLLT (830  nm, 35, 70, 140, and 280 J/cm2) for 21 consecutive days. Functional gait analysis was performed at weekly intervals and the animals were sacrificed after the last evaluation at day 21 for collection of the gastrocnemius muscles, which were submitted to analysis of resistance, and the tibialis anterior, for evaluation of meta...
Source: Lasers in Medical Science - March 6, 2017 Category: Laser Surgery Source Type: research

Impact of low-level laser therapy on hyposalivation, salivary pH, and quality of life in head and neck cancer patients post-radiotherapy
AbstractLate effects of radiotherapy for head and neck cancer treatment have been increasingly investigated due to its impact on patients ’ quality of life. The purpose of this study was to evaluate the effect of low-level laser therapy on hyposalivation, low salivary pH, and quality of life in head and neck cancer patients post-radiotherapy. Twenty-nine patients with radiation-induced xerostomia received laser sessions twice a week , during 3 months (24 sessions). For this, a continuous wave Indium-Gallium-Aluminium-Phosphorus diode laser device was used punctually on the major salivary glands (808 nm, 0.7...
Source: Lasers in Medical Science - March 3, 2017 Category: Laser Surgery Source Type: research

Transcranial LED therapy on amyloid- β toxin 25–35 in the hippocampal region of rats
AbstractExcessive A β deposition in the brain is associated with the formation of senile plaques, and their diffuse distribution is related to Alzheimer’s disease. Thirty rats (EG) were irradiated with light-emitting diode (photobiomodulation (PBM)) in the frontal region of the skull after being inoculated with the Aβ toxin in the hippocampus; 30 rats were used as the control group (CG). The analysis was conducted at 7, 14, and 21 days after irradiation. We observed a decreased in Aβ deposits in treated animals compared with animals in the CG. The behavioral and motor assessment revealed that the ...
Source: Lasers in Medical Science - March 2, 2017 Category: Laser Surgery Source Type: research

Microstructure and corrosion behavior of laser surface-treated AZ31B Mg bio-implant material
AbstractAlthough magnesium and magnesium alloys are considered biocompatible and biodegradable, they suffer from poor corrosion performance in the human body environment. In light of this, surface modification via rapid surface melting of AZ31B Mg alloy using a continuous-wave Nd:YAG laser was conducted. Laser processing was performed with laser energy ranging from 1.06 to 3.18  J/mm2. The corrosion behavior in simulated body fluid of laser surface-treated and untreated AZ31B Mg alloy samples was evaluated using electrochemical technique. The effect of laser surface treatment on phase and microstructure evolution was ...
Source: Lasers in Medical Science - March 2, 2017 Category: Laser Surgery Source Type: research

Effect of radiant heat on conventional glass ionomer cements during setting by using a blue light diode laser system (445  nm)
AbstractThe aim of this in vitro study was to evaluate the effect of radiant heat on surface hardness of three conventional glass ionomer cements (GICs) by using a blue diode laser system (445  nm) and a light-emitting diode (LED) unit. Additionally, the safety of the laser treatment was evaluated. Thirty disk-shaped specimens were prepared of each tested GIC (Equia Fil, Ketac Universal Aplicap and Riva Self Cure). The experimental groups (n = 10) of the study were as follows: group 1 was the control group of the study; in group 2, the specimens were irradiated for 60 s at the top surface using a LE...
Source: Lasers in Medical Science - February 27, 2017 Category: Laser Surgery Source Type: research

Light and laser treatment modalities for disseminated superficial actinic porokeratosis: a systematic review
AbstractTreatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients with DSAP. Systematic review resulted in 14 articles to be included. Photodynamic therapy (PDT) overall was the least successful treatment modality, with clinical improvement seen in a minority of patients (MAL-PDT:N = 9 patients, 33.3% showed improvement; ALA-PDT:N = 3 pat...
Source: Lasers in Medical Science - February 27, 2017 Category: Laser Surgery Source Type: research

Long-term effects of pulsed high-intensity laser therapy in the treatment of post-burn pruritus: a double-blind, placebo-controlled, randomized study
AbstractWe assessed the long-term effects of pulsed high-intensity laser therapy (HILT) in post-burn pruritus treatment. A total of 49 adult burn patients with mean age of 31.53  ± 10.14 years participated, with 24 patients randomly assigned to the active laser group (ALG) and 25 in the placebo laser group (PLG). The ALG received HILT three times per week for 6 weeks, while the PLG received placebo HILT. Both groups received 10-mg cetirizine tablets twice daily and 1 0 mg at bedtime. All patients were advised to massage their burn scars with coconut oil for 5 min four times daily. T...
Source: Lasers in Medical Science - February 23, 2017 Category: Laser Surgery Source Type: research

Vehicle type affects filling of fractional laser-ablated channels imaged by optical coherence tomography
This study aims to elucidate the impact of vehicle type on the filling of MTZs from application of liquid, gel, and cream vehicles. Ex vivo pig skin was exposed to 10,600  nm fractional CO2 laser at 5% density, 120  μm beam diameter, and fluences of 40 and 80 mJ/microbeam (mJ/mb). Six repetitions were performed for each of six interventions (2 fluences and 3 vehicle types,n = 36). MTZ dimensions and filling by vehicle type were evaluated by optical coherence tomography, using blue tissue dye as a contrast-enhancing agent. Outcome measure was degree of MTZ filling assessed as percentages of e...
Source: Lasers in Medical Science - February 17, 2017 Category: Laser Surgery Source Type: research

Non-ablative erbium YAG laser for the treatment of type III stress urinary incontinence (intrinsic sphincter deficiency)
The objective of this pilot study was to determine the safety and efficacy of a new non-ablative erbium YAG laser procedure for the treatment of type III stress urinary incontinence (intrinsic sphincter deficiency) in women. Twenty-two patients with a Valsalva leak point pressure less than 60  cm H2O were recruited and treated with a non-ablative erbium laser delivering low fluence pulses inside the whole length of the urethra through a specially designed cannula. Treatment consisted of two treatment sessions with a 3-week interval in-between. Therapeutic efficacy, as assessed by a ques tionnaire addressing quality of...
Source: Lasers in Medical Science - February 16, 2017 Category: Laser Surgery Source Type: research

The diagnostic accuracy of a laser fluorescence device and digital radiography in detecting approximal caries lesions in posterior permanent teeth: an in vivo study
AbstractThe aim of this in vivo study was to test the diagnostic accuracy of a pen-type laser fluorescence (LFpen) device in detecting approximal caries lesions, in posterior permanent teeth, at the cavitation and non-cavitation thresholds, and compare it with that of digital bitewing radiography. Thirty patients (aged 18 –37), who attended the Faculty of Dentistry at Damascus University for a dental examination, were consecutively screened. Ninety approximal surfaces of posterior permanent teeth without frank cavitations, enamel hypoplasia or restorations were selected and examined using the LFpen (DIAGNOdent pen) a...
Source: Lasers in Medical Science - February 14, 2017 Category: Laser Surgery Source Type: research

Comparison of laser and ozone treatments on oral mucositis in an experimental model
In conclusion, within the limitations of this study, LLLT is more effective than ozone. However, further studies on this subject are required. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 11, 2017 Category: Laser Surgery Source Type: research

Erratum to: Titanium scaffold osteogenesis in healthy and osteoporotic rats is improved by the use of low-level laser therapy (GaAlAs)
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 11, 2017 Category: Laser Surgery Source Type: research

Biochemical changes on the repair of surgical bone defects grafted with biphasic synthetic micro-granular HA + β-tricalcium phosphate induced by laser and LED phototherapies and assessed by Raman spectroscopy
AbstractsThis work aimed the assessment of biochemical changes induced by laser or LED irradiation during mineralization of a bone defect in an animal model using a spectral model based on Raman spectroscopy. Six groups were studied: clot, laser (λ = 780 nm; 70 mW), LED (λ = 850 ± 10 nm; 150 mW), biomaterial (biphasic synthetic micro-granular hydroxyapatite (HA) + β-tricalcium phosphate), biomaterial + laser, and biomaterial + LED. When indicated, defects were further irradiated at a 48-h interval during 2 weeks (20 J/cm2 per ...
Source: Lasers in Medical Science - February 10, 2017 Category: Laser Surgery Source Type: research

Effectiveness of repeated photodynamic therapy in the elimination of intracanal Enterococcus faecalis biofilm: an in vitro study
AbstractThe study aimed to investigate the effectiveness of photodynamic therapy in the elimination of intracanalEnterococcus faecalis biofilm and to analyse how a repeated light irradiation, replenishment of oxygen and photosensitiser affect the results of the photodynamic disinfecting protocol. After chemomechanical preparation, 46 single-rooted human teeth were infected with a clinical strain ofE. faecalis and incubated for a week in microaerobic conditions. The experimental procedures included groups of single application of photodynamic therapy, two cycles of PDT, irrigation with 5.25% NaOCl solution and negative and ...
Source: Lasers in Medical Science - February 10, 2017 Category: Laser Surgery Source Type: research

Applications of picosecond lasers beyond tattoos: pigment reduction and tissue remodeling
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - February 9, 2017 Category: Laser Surgery Source Type: research

The effect of different cleaning methods on the surface and temperature of failed titanium implants: an in vitro study
AbstractThe aims of this in vitro study are to compare the efficacy of different cleaning methods in removing debris of failed implants and to detect thermal changes of the implants treated by various scaling instruments. Twenty-seven failed implants and two unused implants as control were included to this study —group 1: plastic curette (P), group 2: titanium curette (T), group 3: carbon curette (C), group 4: titanium brush (TB), group 5: Er:YAG laser (laser 1 (L1) 100 mJ/pulse at 10 Hz), group 6: Er:YAG laser (laser 2 (L2) 150 mJ/pulse at 10 Hz), group 7: Er:YAG laser (laser 3 (L3) 200 mJ/p...
Source: Lasers in Medical Science - February 4, 2017 Category: Laser Surgery Source Type: research

Treatment for residual stones using flexible ureteroscopy and holmium laser lithotripsy after the management of complex calculi with single-tract percutaneous nephrolithotomy
This study validated the effectiveness and safety of the treatment for residual stones using flexible ureteroscopy (fURS) and holmium laser (0.6 –1.2 J, 20–30 Hz) lithotripsy via a fiber with a 200-μm core diameter and 0.22 numerical aperture (NA) after the management of complex calculi with single-tract percutaneous nephrolithotomy (PCNL). Between January 2014 and June 2016, 27 consecutive patients with complex calculi underwent fURS and holmium laser lithotripsy after a planned single-tract PCNL. Among the 27 patients with complex calculi, 9 had full staghorn calculi, 7 had partial staghorn calcu...
Source: Lasers in Medical Science - February 4, 2017 Category: Laser Surgery Source Type: research

Nd:YAG laser-induced morphology change and photothermal conversion of gold nanorods with potential application in the treatment of port-wine stain
AbstractBased on the principle of selective photothermolysis, 1064  nm Nd:YAG laser has great potential for the treatment of deeper and larger PWS. However, the clinical effectiveness is limited because of the weak absorption of blood to Nd:YAG laser. The aim of this study is to obtain the optimal irradiation conditions to effectively destroy vascular lesions with the assistance of PEG-modified gold NRs to enhance blood absorption of Nd:YAG laser. In our study, PEG-modified gold NRs were prepared by the seeded growth method. Gold NRs after exposure to Nd:YAG laser were characterized using absorption spectra and transm...
Source: Lasers in Medical Science - February 3, 2017 Category: Laser Surgery Source Type: research

Photobiomodulation laser and pulsed electrical field increase the viability of the musculocutaneous flap in diabetic rats
AbstractThe purpose of this study is to investigate the effect of pulsed electrical field (PEF) and photobiomodulation laser (PBM) on the viability of the TRAM flap in diabetic rats. Fifty Wistar rats were divided into five homogeneous groups: Group 1 —control; Group 2—diabetics; Group 3—diabetics + PEF; Group 4—diabetic + laser 660 nm, 10 J/cm2, 0.27  J; Group 5—diabetic + laser 660 nm, 140 J/cm2, 3.9  J. The percentage of necrotic area was evaluated using software Image J®. The peripheral circulation of the flap was evaluated by infrared thermography FLIR T4...
Source: Lasers in Medical Science - February 2, 2017 Category: Laser Surgery Source Type: research

Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers
This study was conducted to evaluate the efficacy of low-level laser therapy (LLLT) for the treatment of diabetic foot ulcers in a tertiary care centre (Department of Surgery, Mahatma Gandhi Memorial Medical College and Maharaja Yashwantrao Hospital, A.B. Road, Indore). A total of 30 patients with type 2 DM having Meggitt-Wagner grade I foot ulcers of more than 6  weeks duration with negative culture were studied. Patients were randomized into two groups of 15 each. Patients in study group received LLLT (660 ± 20 nm, 3 J/cm2) along with conventional therapy and those in control group wer...
Source: Lasers in Medical Science - February 1, 2017 Category: Laser Surgery Source Type: research

Laser and LED phototherapy on midpalatal suture after rapid maxilla expansion: Raman and histological analysis
AbstractThe aim of this study was to analyze the effect of laser or LED phototherapy on the acceleration of bone formation at the midpalatal suture after rapid maxilla expansion. Forty-five rats were divided into groups at 7  days (control, expansion, expansion and laser irradiation, and expansion and LED irradiation) and into 14 days (expansion, expansion and laser in the 1st week, expansion and LED in the 1st week, expansion and laser in the 1st and 2nd weeks, expansion and LED in the 1st and 2nd weeks). Laser/LED i rradiation occurred every 48 h. Expansion was accomplished with a spatula and maintained wi...
Source: Lasers in Medical Science - February 1, 2017 Category: Laser Surgery Source Type: research

Application of reflectance confocal microscopy to evaluate skin damage after irradiation with an yttrium-scandium-gallium-garnet (YSGG) laser
The objective of this study was to observe the characteristics of the skin after irradiation with a 2790-nm yttrium-scandium-gallium-garnet (YSGG) laser using reflectance confocal microscopy (RCM). A 2790-nm YSGG laser was used to irradiate fresh foreskin (four doses, at spot density 3) in vitro. The characteristics of microscopic ablative columns (MAC), thermal coagulation zone (TCZ), and microscopic treatment zones (MTZ) were observed immediately after irradiation using digital microscope and RCM. The characteristics of MAC, TCZ, and MTZ with variations in pulse energy were comparatively analyzed. After irradiation, MAC,...
Source: Lasers in Medical Science - February 1, 2017 Category: Laser Surgery Source Type: research

A review of the mechanism of action of lasers and photodynamic therapy for onychomycosis
AbstractOnychomycosis is one of the most common diseases in the field of dermatology. It refers to the fungal infection of the nail plate or nail bed with high incidence in the general population. The available treatment options for onychomycosis have limited use due to side effects, drug interactions, and contraindications, which necessitates the application of an alternative treatment for onychomycosis. In the recent years, lasers and photodynamic therapy (PDT) have been recognized as alternative treatment options. Most of the previous studies have found them to be safe and effective treatment modalities in this indicati...
Source: Lasers in Medical Science - February 1, 2017 Category: Laser Surgery Source Type: research

The effect of pre-operative topical anaesthetic cream on the ablative width and coagulative depth of ablative fractional resurfacing laser
The objective of the study was to compare the ablative width (AW) and coagulative depth (CD) of AFR laser with and without pre-treatment with TAC. Four Thai females who underwent abdominoplasty were included in the study. The excised skin of each subject was divided into four areas. TAC (eutectic mixture of local anaesthesia; EMLA) with 1-h occlusion was applied only on the first and second areas. The first and third areas were treated with FCO2 at 15  mj and 5% density. The second and fourth areas were treated with FEr:YAG at 28 J/cm2 and 5% density. Six biopsied specimens were obtained from each area. A total o...
Source: Lasers in Medical Science - February 1, 2017 Category: Laser Surgery Source Type: research

Photobiostimulation reverses allodynia and peripheral nerve damage in streptozotocin-induced type 1 diabetes
AbstractFor better evaluation of the efficacy of low-level laser therapy in treating painful diabetic neuropathy and in protecting nerve fiber damage, we conducted a study with type 1 diabetic rats induced by streptozotocin. It is well known that diabetic peripheral neuropathy is the leading cause of pain in those individuals who suffer from diabetes. Despite the efficacy of insulin in controlling glucose level in blood, there is no effective treatment to prevent or reverse neuropathic damage for total pain relief.Male Wistar rats were divided into saline, vehicle, and treatment groups. A single intraperitoneal (i.p.) inje...
Source: Lasers in Medical Science - January 30, 2017 Category: Laser Surgery Source Type: research

Pars plana vitrectomy with 360 ° versus localized laser retinopexy in the management of retinal detachment with undetected breaks intraoperatively: a retrospective, comparative, interventional study
AbstractThe purpose of this study is to compare the efficacy of intraoperative 360 ° and localized laser retinopexy in 23-gauge pars plana vitrectomy (PPV) for rhegmatogenous retinal detachments (RRD) with undetected retinal breaks intraoperatively. This is a retrospective, comparative, interventional study. Medical records of 48 consecutive eyes with RRD of intraoperative undete cted retinal breaks were reviewed. Nineteen patients (group I) received 360° laser retinopexy in PPV, while the remaining 29 patients (group II) underwent localized laser retinopexy. In group I, a triple row of confluent medium-white laser...
Source: Lasers in Medical Science - January 30, 2017 Category: Laser Surgery Source Type: research

Influence of irradiation by a novel CO 2 9.3- μm short-pulsed laser on sealant bond strength
The objective of this in vitro study was to evaluate whether irradiation of enamel with a novel CO2 9.3- μm short-pulsed laser using energies that enhance caries resistance influences the shear bond strength of composite resin sealants to the irradiated enamel. Seventy bovine and 240 human enamel samples were irradiated with a 9.3-μm carbon dioxide laser (Solea, Convergent Dental, Inc., Natick, MA) w ith four different laser energies known to enhance caries resistance or ablate enamel (pulse duration from 3 μs at 1.6 mJ/pulse to 43 μs at 14.9 mJ/pulse with fluences between 3.3 and 30.4 ...
Source: Lasers in Medical Science - January 29, 2017 Category: Laser Surgery Source Type: research

Efficacy and safety of far infrared radiation in lymphedema treatment: clinical evaluation and laboratory analysis
AbstractSwelling is the most common symptom of extremities lymphedema. Clinical evaluation and laboratory analysis were conducted after far infrared radiation (FIR) treatment on the main four components of lymphedema: fluid, fat, protein, and hyaluronan. Far infrared radiation is a kind of hyperthermia therapy with several and additional benefits as well as promoting microcirculation flow and improving collateral lymph circumfluence. Although FIR therapy has been applied for several years on thousands of lymphedema patients, there are still few studies that have reported the biological effects of FIR on lymphatic tissue. I...
Source: Lasers in Medical Science - January 26, 2017 Category: Laser Surgery Source Type: research

Laser-assisted topical corticosteroid delivery for the treatment of keloids
The objectives of this study are to evaluate the clinical benefit of laser-assisted corticosteroid delivery and to compare this technique to corticosteroid intralesional injection, a standard treatment for keloids. Patients with keloids on the left shoulder after BCG vaccination were enrolled in this study. The entire lesion was first treated with an ablative fractional erbium-YAG laser. After this treatment, the lesion was divided into two halves. The first half received an intralesional injection of corticosteroid, whereas the second half received topical application of corticosteroids that were occluded for 3 hours. Fou...
Source: Lasers in Medical Science - January 26, 2017 Category: Laser Surgery Source Type: research

Sinonasal quality of life outcomes following laser treatment of epistaxis related to hereditary hemorrhagic telangiectasia
In this study, we aim to (1) characterize baseline sinonasal symptoms for HHT patients and to (2) analyze changes in sinonasal symptoms before and after laser surgical treatment for HHT. We performed a retrospective chart review of sinonasal outcome test-22 (SNOT-22) scores before and after one or more laser surgical treatments for HHT-related epistaxis between January 1, 2010 and December 1, 2015 at a tertiary academic medical center with an HHT Foundation-approved Center of Excellence. Preoperative and all subsequent postoperative SNOT-22 scores (short-term,
Source: Lasers in Medical Science - January 24, 2017 Category: Laser Surgery Source Type: research

A randomized controlled clinical and histopathological trial comparing excisional biopsies of oral fibrous hyperplasias using CO 2 and Er:YAG laser
This study was conducted in order to compare clinical and histopathological outcomes for excisional biopsies when using pulsed CO2 laser versus Er:YAG laser. Patients (n = 32) with a fibrous hyperplasia in the buccal mucosa were randomly allocated to the CO2 (140  Hz, 400 μs, 33 mJ) or the Er:YAG laser (35 Hz, 297 μs, 200 mJ) group. The duration of excision, intraoperative bleeding and methods to stop the bleeding, postoperative pain (VAS; ranging 0–100), the use of analgesics, and the width of the thermal damage zone (μm) were recorded and compar ed between the tw...
Source: Lasers in Medical Science - January 24, 2017 Category: Laser Surgery Source Type: research

Investigation of photobiomodulation potentiality by 635 and 809  nm lasers on human osteoblasts
This study suggests that several irradiation parameters and variations in the methods should be clearly established in the laboratory before laser treatment becomes a postulated application for bone tissue regeneration in clinical level. (Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 23, 2017 Category: Laser Surgery Source Type: research

Low-level laser therapy in the treatment of pressure ulcers: systematic review
AbstractThe aim of this study was to evaluate the effects of low-level laser therapy (LLT) in pressure ulcers (PU) in humans through a systematic review of randomized studies. The search includes the databases MEDLINE, PEDro, Cochrane CENTRAL, and Lilacs, as well a manual search until May, 2016. This included randomized clinical trials of LLT compared with other interventions, different types of LLT, LLT placebo, or control in the treatment of PU. The outcomes evaluated were the ulcer area, healing rate, and overall healing rate. The risk of bias was evaluated using the tool of the Cochrane Collaboration, and the results w...
Source: Lasers in Medical Science - January 23, 2017 Category: Laser Surgery Source Type: research

Comparison of the local effects of a 600- μm bare fibre at high laser power on lung parenchyma: Nd:YAG laser 1320 vs. 1064 nm
AbstractLung metastases are often resected non-anatomically with a laser using a diode-pumped Nd:YAG laser at a wavelength of 1320  nm with a laser output of up to 60 W. Usually the removal of lesions is carried out in contact mode by means of a bare fibre. We compared the local effects of an Nd:YAG laser at a wavelength of 1064 nm with those at a wavelength of 1320 nm using a 600-μm bare fibre in contact mode in an experi mental model. The investigations were carried out on porcine lungs freshly withdrawn at the abattoir. The 600-μm laser fibre was fixed vertically in contact with the lung surfac...
Source: Lasers in Medical Science - January 21, 2017 Category: Laser Surgery Source Type: research

Diagnostic validity of ICDAS and DIAGNOdent combined: an in vitro study in pre-cavitated lesions
AbstractIn a continuous process such as caries, it is important to possess criteria or instruments that allow the lesions to be diagnosed at early stages so that preventive or interceptive treatments can be applied before cavitation takes place. The present study seeks to assess the diagnostic efficacy of the International Caries Detection and Assessment System (ICDAS II) criteria and the DIAGNOdent laser fluorescence (LF) pen in occlusal caries lesions, using histological sections as the gold standard. Sixty-four permanent teeth were examined by two researchers who previously performed and calibrated both the ICDAS II cri...
Source: Lasers in Medical Science - January 18, 2017 Category: Laser Surgery Source Type: research

Repeated applications of photodynamic therapy on Candida glabrata biofilms formed in acrylic resin polymerized
In this study, we evaluated the effects of multiple sessions of PDT onCandida glabrata biofilms in specimens of polymerized acrylic resin formed after 5  days. Subsequently, four applications of PDT were performed on biofilms in 24-h intervals (days 6–9). Also, we evaluated two types of PDT, including application of laser and methylene blue or light-emitting diode (LED) and erythrosine. The control groups were treated with physiological solution. The effects of PDT on biofilm were evaluated after the first and fourth application of PDT. The biofilm analysis was performed by counting the colony-forming units. The...
Source: Lasers in Medical Science - January 14, 2017 Category: Laser Surgery Source Type: research

Dynamic optical absorption characteristics of blood after slow and fast heating
AbstractLaser treatment is the most effective therapy in dermatology for vascular skin disorders, such as port-wine stains (PWS). Changes in heat-induced absorbance in blood must be determined for accurate numerical simulation and implementation of multi-pulse laser therapy for treatment of PWS. Thermally induced absorbance changes in hemoglobin in blood were compared in vitro between slow water bath heating and fast heating irradiated by using sub-millisecond Nd:YAG laser. Blood composition at different temperatures was calculated by comparing blood absorption spectra with those of pure HbO2, Hb, and metHb at room tempera...
Source: Lasers in Medical Science - January 13, 2017 Category: Laser Surgery Source Type: research

A novel combination treatment to stimulate bone healing and regeneration under hypoxic conditions: photobiomodulation and melatonin
AbstractMelatonin has anabolic effects on the bone, even under hypoxia, and laser irradiation has been shown to improve osteoblastic differentiation. The aim of this study was to investigate whether laser irradiation and melatonin would have synergistic effects on osteoblastic differentiation and mineralization under hypoxic conditions. MC3T3-E1 cells were exposed to 1% oxygen tension for the hypoxia condition. The cells were divided into four groups: G1-osteoblast differentiation medium only (as the hypoxic condition), G2-treatment with 50  μM melatonin only, G3-laser irradiation (808 nm, 80 mW, GaAlAs d...
Source: Lasers in Medical Science - January 13, 2017 Category: Laser Surgery Source Type: research

Efficacy of pulsed Nd:YAG laser in the treatment of patients with knee osteoarthritis: a randomized controlled trial
AbstractThe purpose of this study was to investigate the effects of pulsed Nd:YAG laser plus glucosamine/chondroitin sulfate (GCS) in patients with knee osteoarthritis (KOA) by examining changes in pain and knee function, as well as synovial thickness (ST) and femoral cartilage thickness (FCT). Sixty-seven male patients participated, with a mean (SD) age of 53.85 (4.39) years, weight of 84.01 (4.70) kg, height of 171.51 (3.96) cm, and BMI of 28.56 (1.22). Group 1 was treated with high-intensity laser therapy (HILT), GCS, and exercises (HILT  + GCS + EX). Group 2 was treated with GCS plus exercis...
Source: Lasers in Medical Science - January 11, 2017 Category: Laser Surgery Source Type: research

Pulsed dye laser on ecchymoses: clinical and histological assessment
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 11, 2017 Category: Laser Surgery Source Type: research

Clinical effectiveness of low-level laser treatment on peripheral somatosensory neuropathy
AbstractPeripheral sensory neuropathy treatment is one of the common treatment problems and causes morbidity and mortality in people suffering from that. Although treatment depends on the underlying cause of the condition, nevertheless, in some cases, there is no cure for it, and it requires palliative and symptomatic treatment. In laboratory studies, low-level laser has been effective in the nerves protection and restoration. The aim of this article is to investigate the clinical efficacy of low-level laser on improvement of the peripheral somatosensory neuropathy. Search in the articles published up to 30 October 2015 (f...
Source: Lasers in Medical Science - January 10, 2017 Category: Laser Surgery Source Type: research

Analysis of the variation in low-level laser energy density on the crushed sciatic nerves of rats: a morphological, quantitative, and morphometric study
The objective of this study was to evaluate three energy densities of low-level laser therapy (LLLT, GaAlAs, 780  nm, 40 mW, 0.04 cm2) for the treatment of lesions to peripheral nerves using the sciatic nerve of rats injured via crushing model (15  kgf, 5.2 MPa). Thirty Wistar rats (♂, 200–250 g) were divided into five groups (n = 6): C—control, not injured, and irradiated; L0—injured nerve without irradiation; L4—injured nerve irradiated with LLLT 4 J/cm2 (0.16  J); L10—injured nerve irradiated with LLLT 10 J/cm2 (0.4  J); and ...
Source: Lasers in Medical Science - January 7, 2017 Category: Laser Surgery Source Type: research

The photobiomodulation effect of higher-fluence 808-nm laser therapy with a flat-top handpiece on the wound healing of the earthworm Dendrobaena veneta : a brief report
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - January 6, 2017 Category: Laser Surgery Source Type: research

Does photobiomodulation therapy is better than cryotherapy in muscle recovery after a high-intensity exercise? A randomized, double-blind, placebo-controlled clinical trial
This study aimed to determine the effectiveness of photobiomodulation therapy (PBMT) and cryotherapy, in isolated and combined forms, as muscle recovery techniques after muscle fatigue-inducing protocol. Forty volunteers were randomly divided into five groups: a placebo group (PG); a PBMT group (PBMT); a cryotherapy group (CG); a cryotherapy-PBMT group (CPG); and a PBMT-cryotherapy group (PCG). All subjects performed four sessions at 24-h intervals, during which they submitted to isometric assessment (MVC) and blood collection in the pre-exercise period, and 5 and 60  min post-exercise, while the muscle fatigue induct...
Source: Lasers in Medical Science - January 5, 2017 Category: Laser Surgery Source Type: research